Call for Papers:Vol.11 Issue.4

Submission
Last date		 28-Aug-2025
Acceptance Status In One Day
Paper Publish In Two Days
Submit ManuScript

News & Updates

Submit Article

Dear Authors, Article publish in our journal for Volume-11,Issue-4. For article submission on below link: Submit Manuscript


Join As Board

Dear Reviewer, You can join our Reviewer team without given any charges in our journal. Submit Details on below link: Join As Board


Paper Publication Charges

IJARIIE APP
Download Android App

For Authors

Archives

IJARIIE Board

Downloads

Android App

Download IJARIIE APP

Authors

Title: :  A Study of Structural Basis of Collagen-GPVI Interaction
PaperId: :  14809
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 4 Issue 1 2018
DUI:    16.0415/IJARIIE-14809
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Suresh Yadav SinganaboinaResearch Scholar, Department of Biotechnology, Sri Satya Sai University of Technology & Medical Sciences, Sehore, M.P., India.
Dr. Syed Shahab AhmedResearch Supervisor Department of Biotechnology, Sri Satya Sai University of Technology &Medical Sciences, Sehore, M.P., India.

Abstract

Biotechnology
Collagen-GPVI Interaction, 3-dimensional aggregates, blood flow, GPVI enhances
While the immune-type GPVI receptor activates platelets, the way this receptor developed into a platelet under rapid blood flow conditions is not understood. Moreover, the preservation of collagen reactions in non-mammalian animals not expressing GPVI is not apparent. According to this research, the proline-rich GPVI domain enhances GPVI signalling kinetics and is required for maximal adherence to flow collagen. The proline-rich domain accelerates signalling by binding and directly activating the Src family Lyn kinase. Collagen stimulates chicken thrombocytes, but, in strong contrast to platelet activity, they do not form 3-dimensional aggregates under circumstances of arterial flow. Despite being selective, thrombocytes exhibit a decreased integrin density of 2b3 on the cell's surface, with most platelet-specific genes expressed. These results reveal that the GPVI enhances immune signalling kinetics by means of a novel molecular mechanism and demonstrate that weather-cell responses to collagen under flow are partly maintained. In conjunction with stimulus-specific tyrosine phosphorylation of the GPVI/FcR-chain complex and/or CLEC-2, Src and Syk tyrosine kinases are responsible for aggregation of human and mouse platelet. Receptor-deficient platelets show a key role in mediating aggregation for GPVI and/or CLEC-2.

Citations

Copy and paste a formatted citation or use one of the links to import into a bibliography manager and reference.

IJARIIE Suresh Yadav Singanaboina, and Dr. Syed Shahab Ahmed. "A Study of Structural Basis of Collagen-GPVI Interaction" International Journal Of Advance Research And Innovative Ideas In Education Volume 4 Issue 1 2018 Page 1493-1499
MLA Suresh Yadav Singanaboina, and Dr. Syed Shahab Ahmed. "A Study of Structural Basis of Collagen-GPVI Interaction." International Journal Of Advance Research And Innovative Ideas In Education 4.1(2018) : 1493-1499.
APA Suresh Yadav Singanaboina, & Dr. Syed Shahab Ahmed. (2018). A Study of Structural Basis of Collagen-GPVI Interaction. International Journal Of Advance Research And Innovative Ideas In Education, 4(1), 1493-1499.
Chicago Suresh Yadav Singanaboina, and Dr. Syed Shahab Ahmed. "A Study of Structural Basis of Collagen-GPVI Interaction." International Journal Of Advance Research And Innovative Ideas In Education 4, no. 1 (2018) : 1493-1499.
Oxford Suresh Yadav Singanaboina, and Dr. Syed Shahab Ahmed. 'A Study of Structural Basis of Collagen-GPVI Interaction', International Journal Of Advance Research And Innovative Ideas In Education, vol. 4, no. 1, 2018, p. 1493-1499. Available from IJARIIE, http://ijariie.com/AdminUploadPdf/A_Study_of_Structural_Basis_of_Collagen_GPVI_Interaction_ijariie14809.pdf (Accessed : 01 July 2021).
Harvard Suresh Yadav Singanaboina, and Dr. Syed Shahab Ahmed. (2018) 'A Study of Structural Basis of Collagen-GPVI Interaction', International Journal Of Advance Research And Innovative Ideas In Education, 4(1), pp. 1493-1499IJARIIE [Online]. Available at: http://ijariie.com/AdminUploadPdf/A_Study_of_Structural_Basis_of_Collagen_GPVI_Interaction_ijariie14809.pdf (Accessed : 01 July 2021)
IEEE Suresh Yadav Singanaboina, and Dr. Syed Shahab Ahmed, "A Study of Structural Basis of Collagen-GPVI Interaction," International Journal Of Advance Research And Innovative Ideas In Education, vol. 4, no. 1, pp. 1493-1499, Jan-Feb 2018. [Online]. Available: http://ijariie.com/AdminUploadPdf/A_Study_of_Structural_Basis_of_Collagen_GPVI_Interaction_ijariie14809.pdf [Accessed : 01 July 2021].
Turabian Suresh Yadav Singanaboina, and Dr. Syed Shahab Ahmed. "A Study of Structural Basis of Collagen-GPVI Interaction." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 4 number 1 (01 July 2021).
Vancouver Suresh Yadav Singanaboina, and Dr. Syed Shahab Ahmed. A Study of Structural Basis of Collagen-GPVI Interaction. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2018 [Cited : 01 July 2021]; 4(1) : 1493-1499. Available from: http://ijariie.com/AdminUploadPdf/A_Study_of_Structural_Basis_of_Collagen_GPVI_Interaction_ijariie14809.pdf
BibTex EndNote RefMan RefWorks

Number Of Downloads


Last download on 7/1/2021 6:53:17 AM

Save in Google Drive

Similar-Paper

TitleArea of ResearchAuther NameAction
Real-Time Hand Gesture Recognition with Finger Counting (Using OpenCV and Mediapipe)Computer scienceBhumika Sahu Download
Diffie Hellman Key Exchange Algorithm with Man in the middle attack (MITM)Computer Science EngineeringMahesh Purushottam Gajbhiye Download
AN IMPROVED ATTRIBUTE BASED ACCESS CONTROL IN PERSONAL HEALTH RECORDS USING CLOUD WITH CONSTANT CIPHERTEXT LENGTHScience and TechBitrus Isahaka Dzarma Download
Driver Drowsiness Detection System By Measuring EAR and MARComputer Engineering Zoya Fatema Khan Download
Cloud-Based File Storage and Sharing Web ApplicationComputer Science & EngineeringMohammed Aadil Download
STUDYNEST: ONLINE LEARNING PLATFORM WITH AI RECOMMENDATION SYSTEMComputer Science and Engineering Urvashi Suresh Waghmare Download
Leveraging AWS for Developing and Hosting a Dynamic Food Ordering Web ApplicationComputer EngineeringAfshin Khanam Download
Edge-to-Cloud Synergy: An Autoencoder-GAN Framework for Anomaly Detection in Healthcare Records, Financial Statements, and Secure Cloud StorageInformation TechnologyKarthik Kushala Download
E-Commerce Fraud Detection Based on Machine Learning TechniquesComputer Science EngneeringVikram Ankush Ade Download
Detection of Phishing Website Using Gradient Boosting AlgorithmComputer Science and EngineeringYAWALKAR PRASAD PRAMOD Download
Property Dealing WebComputer Science EngineeringYash Chaudhari Download
Reinforcement Learning for the Evolution of Antimicrobial Nano formulationsmachine learningMadhusudan Download
SecuraVault: A secured blockchain based cloud storage systemComputer Engineering Anshika Jaiswal Download
Autoimmune Disease Detection in women Using Machine Learning Approachcomputer science EngineeringJ. L. V. S. Download
Medicine Overdose Detection System Using Machine LearningComputer Science EngineeringDr.Somashekhar B M Download
12