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Title: :  EVALUATION OF HEPATOPROTECTIVE AND ANTIDIABETIC EFFECTS OF ETHANOLIC EXTRACT OF DIOSPYROS EBENUM IN STREPTOZOTOCIN INDUCED DIABETIC
PaperId: :  17327
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 8 Issue 3 2022
DUI:    16.0415/IJARIIE-17327
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Dr. Vijayabhaskar KanakamSt. Peters Institute of Phrmaceutical Sciences, Warangal, Telangana, India.

Abstract

pharmacy
Diospyros EBENUM, Hepatoprotective, Histopathology, Streptozotocin, Hepatic enzymes, Hepatic cytoarchitecture.
Hepatoprotective Effect of Ethanolic extract of Diospyros EBENUM (EDE) in streptozotocin (STZ) 45mg/kg body weight induced diabetic rats was studied. Oral administration of Ethanolic extract of Diospyros EBENUM (EDE) to diabetic induced rats at a dose of 500 mg/kg body weight resulted in significant reduction of elevated blood glucose and hepatic transaminase enzyme levels, at different treatment period (0th day, 21st day, and45th day) which also showed the structural changes in hepatic architecture of STZ induced diabetic rats. The EDE treated diabetic rats were significantly recovered from hepatotoxicity, by analyzing various physical, biochemical parameters like body weight, fasting plasma glucose levels, Serum glutamate oxaloacetate transaminase (SGOT), Serum glutamate pyruvate transaminase (SGPT) and Alkaline phosphatase (ALP) levels. Further the histopathology results of EDE treated rats also confirmed the significant recovery of liver damage. Our study confirmed the therapeutic hepatoprotective effect of EDE in diabetic treated rats.

Citations

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IJARIIE Dr. Vijayabhaskar Kanakam. "EVALUATION OF HEPATOPROTECTIVE AND ANTIDIABETIC EFFECTS OF ETHANOLIC EXTRACT OF DIOSPYROS EBENUM IN STREPTOZOTOCIN INDUCED DIABETIC" International Journal Of Advance Research And Innovative Ideas In Education Volume 8 Issue 3 2022 Page 3914-3920
MLA Dr. Vijayabhaskar Kanakam. "EVALUATION OF HEPATOPROTECTIVE AND ANTIDIABETIC EFFECTS OF ETHANOLIC EXTRACT OF DIOSPYROS EBENUM IN STREPTOZOTOCIN INDUCED DIABETIC." International Journal Of Advance Research And Innovative Ideas In Education 8.3(2022) : 3914-3920.
APA Dr. Vijayabhaskar Kanakam. (2022). EVALUATION OF HEPATOPROTECTIVE AND ANTIDIABETIC EFFECTS OF ETHANOLIC EXTRACT OF DIOSPYROS EBENUM IN STREPTOZOTOCIN INDUCED DIABETIC. International Journal Of Advance Research And Innovative Ideas In Education, 8(3), 3914-3920.
Chicago Dr. Vijayabhaskar Kanakam. "EVALUATION OF HEPATOPROTECTIVE AND ANTIDIABETIC EFFECTS OF ETHANOLIC EXTRACT OF DIOSPYROS EBENUM IN STREPTOZOTOCIN INDUCED DIABETIC." International Journal Of Advance Research And Innovative Ideas In Education 8, no. 3 (2022) : 3914-3920.
Oxford Dr. Vijayabhaskar Kanakam. 'EVALUATION OF HEPATOPROTECTIVE AND ANTIDIABETIC EFFECTS OF ETHANOLIC EXTRACT OF DIOSPYROS EBENUM IN STREPTOZOTOCIN INDUCED DIABETIC', International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 3, 2022, p. 3914-3920. Available from IJARIIE, http://ijariie.com/AdminUploadPdf/EVALUATION_OF_HEPATOPROTECTIVE_AND_ANTIDIABETIC_EFFECTS_OF_ETHANOLIC_EXTRACT_OF_DIOSPYROS_EBENUM_IN_STREPTOZOTOCIN_INDUCED_DIABETIC_ijariie17327.pdf (Accessed : 22 September 2023).
Harvard Dr. Vijayabhaskar Kanakam. (2022) 'EVALUATION OF HEPATOPROTECTIVE AND ANTIDIABETIC EFFECTS OF ETHANOLIC EXTRACT OF DIOSPYROS EBENUM IN STREPTOZOTOCIN INDUCED DIABETIC', International Journal Of Advance Research And Innovative Ideas In Education, 8(3), pp. 3914-3920IJARIIE [Online]. Available at: http://ijariie.com/AdminUploadPdf/EVALUATION_OF_HEPATOPROTECTIVE_AND_ANTIDIABETIC_EFFECTS_OF_ETHANOLIC_EXTRACT_OF_DIOSPYROS_EBENUM_IN_STREPTOZOTOCIN_INDUCED_DIABETIC_ijariie17327.pdf (Accessed : 22 September 2023)
IEEE Dr. Vijayabhaskar Kanakam, "EVALUATION OF HEPATOPROTECTIVE AND ANTIDIABETIC EFFECTS OF ETHANOLIC EXTRACT OF DIOSPYROS EBENUM IN STREPTOZOTOCIN INDUCED DIABETIC," International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 3, pp. 3914-3920, May-Jun 2022. [Online]. Available: http://ijariie.com/AdminUploadPdf/EVALUATION_OF_HEPATOPROTECTIVE_AND_ANTIDIABETIC_EFFECTS_OF_ETHANOLIC_EXTRACT_OF_DIOSPYROS_EBENUM_IN_STREPTOZOTOCIN_INDUCED_DIABETIC_ijariie17327.pdf [Accessed : 22 September 2023].
Turabian Dr. Vijayabhaskar Kanakam. "EVALUATION OF HEPATOPROTECTIVE AND ANTIDIABETIC EFFECTS OF ETHANOLIC EXTRACT OF DIOSPYROS EBENUM IN STREPTOZOTOCIN INDUCED DIABETIC." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 8 number 3 (22 September 2023).
Vancouver Dr. Vijayabhaskar Kanakam. EVALUATION OF HEPATOPROTECTIVE AND ANTIDIABETIC EFFECTS OF ETHANOLIC EXTRACT OF DIOSPYROS EBENUM IN STREPTOZOTOCIN INDUCED DIABETIC. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2022 [Cited : 22 September 2023]; 8(3) : 3914-3920. Available from: http://ijariie.com/AdminUploadPdf/EVALUATION_OF_HEPATOPROTECTIVE_AND_ANTIDIABETIC_EFFECTS_OF_ETHANOLIC_EXTRACT_OF_DIOSPYROS_EBENUM_IN_STREPTOZOTOCIN_INDUCED_DIABETIC_ijariie17327.pdf
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