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Title: :  MITIGATING EFFECT OF L-ASCORBIC ACID ON DNA CONTENT ALTERATIONS CAUSED BY PROFENOFOS IN LAMELLIDENS MARGINALIS (LAMARCK)
PaperId: :  26839
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 11 Issue 3 2025
DUI:    16.0415/IJARIIE-26839
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Dr. Prakash D. PulateDepartment of Zoology, Padmashri Vikhe Patil College of Arts, Science and Commerce, Pravaranagar Tal- Rahata Dist- Ahilyanagar
Dr. Ram S. TambeDepartment of Zoology, Arts, Commerce and Science College, Satral Tal- Rahuri Dist- Ahilyanagar

Abstract

Biology
L-Ascorbic acid, Profenofos, DNA and Lamellidens marginalis
The present study investigates the genotoxic effects of chronic exposure to the organophosphate pesticide profenofos and the potential protective role of L-ascorbic acid (vitamin C) in the freshwater bivalve Lamellidens marginalis. Bivalves were divided into control and experimental groups, with treatments including profenofos exposure alone and in combination with L-ascorbic acid (50 mg/L), followed by a recovery phase in normal and L-ascorbic acid enriched water. DNA content was quantified in various tissues (gills, gonads, digestive gland, mantle, foot, and whole soft body mass) using the diphenylamine method. Results showed a significant, time-dependent reduction in DNA content across all tissues following profenofos exposure. However, co-exposure to L-ascorbic acid significantly mitigated DNA damage, and recovery in vitamin C-treated water led to a faster and more complete restoration of DNA levels compared to natural recovery.

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IJARIIE Dr. Prakash D. Pulate, and Dr. Ram S. Tambe. "MITIGATING EFFECT OF L-ASCORBIC ACID ON DNA CONTENT ALTERATIONS CAUSED BY PROFENOFOS IN LAMELLIDENS MARGINALIS (LAMARCK)" International Journal Of Advance Research And Innovative Ideas In Education Volume 11 Issue 3 2025 Page 2907-2914
MLA Dr. Prakash D. Pulate, and Dr. Ram S. Tambe. "MITIGATING EFFECT OF L-ASCORBIC ACID ON DNA CONTENT ALTERATIONS CAUSED BY PROFENOFOS IN LAMELLIDENS MARGINALIS (LAMARCK)." International Journal Of Advance Research And Innovative Ideas In Education 11.3(2025) : 2907-2914.
APA Dr. Prakash D. Pulate, & Dr. Ram S. Tambe. (2025). MITIGATING EFFECT OF L-ASCORBIC ACID ON DNA CONTENT ALTERATIONS CAUSED BY PROFENOFOS IN LAMELLIDENS MARGINALIS (LAMARCK). International Journal Of Advance Research And Innovative Ideas In Education, 11(3), 2907-2914.
Chicago Dr. Prakash D. Pulate, and Dr. Ram S. Tambe. "MITIGATING EFFECT OF L-ASCORBIC ACID ON DNA CONTENT ALTERATIONS CAUSED BY PROFENOFOS IN LAMELLIDENS MARGINALIS (LAMARCK)." International Journal Of Advance Research And Innovative Ideas In Education 11, no. 3 (2025) : 2907-2914.
Oxford Dr. Prakash D. Pulate, and Dr. Ram S. Tambe. 'MITIGATING EFFECT OF L-ASCORBIC ACID ON DNA CONTENT ALTERATIONS CAUSED BY PROFENOFOS IN LAMELLIDENS MARGINALIS (LAMARCK)', International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 3, 2025, p. 2907-2914. Available from IJARIIE, http://ijariie.com/AdminUploadPdf/MITIGATING_EFFECT_OF_L_ASCORBIC_ACID_ON_DNA_CONTENT_ALTERATIONS_CAUSED_BY_PROFENOFOS_IN_LAMELLIDENS_MARGINALIS__LAMARCK__ijariie26839.pdf (Accessed : ).
Harvard Dr. Prakash D. Pulate, and Dr. Ram S. Tambe. (2025) 'MITIGATING EFFECT OF L-ASCORBIC ACID ON DNA CONTENT ALTERATIONS CAUSED BY PROFENOFOS IN LAMELLIDENS MARGINALIS (LAMARCK)', International Journal Of Advance Research And Innovative Ideas In Education, 11(3), pp. 2907-2914IJARIIE [Online]. Available at: http://ijariie.com/AdminUploadPdf/MITIGATING_EFFECT_OF_L_ASCORBIC_ACID_ON_DNA_CONTENT_ALTERATIONS_CAUSED_BY_PROFENOFOS_IN_LAMELLIDENS_MARGINALIS__LAMARCK__ijariie26839.pdf (Accessed : )
IEEE Dr. Prakash D. Pulate, and Dr. Ram S. Tambe, "MITIGATING EFFECT OF L-ASCORBIC ACID ON DNA CONTENT ALTERATIONS CAUSED BY PROFENOFOS IN LAMELLIDENS MARGINALIS (LAMARCK)," International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 3, pp. 2907-2914, May-Jun 2025. [Online]. Available: http://ijariie.com/AdminUploadPdf/MITIGATING_EFFECT_OF_L_ASCORBIC_ACID_ON_DNA_CONTENT_ALTERATIONS_CAUSED_BY_PROFENOFOS_IN_LAMELLIDENS_MARGINALIS__LAMARCK__ijariie26839.pdf [Accessed : ].
Turabian Dr. Prakash D. Pulate, and Dr. Ram S. Tambe. "MITIGATING EFFECT OF L-ASCORBIC ACID ON DNA CONTENT ALTERATIONS CAUSED BY PROFENOFOS IN LAMELLIDENS MARGINALIS (LAMARCK)." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 11 number 3 ().
Vancouver Dr. Prakash D. Pulate, and Dr. Ram S. Tambe. MITIGATING EFFECT OF L-ASCORBIC ACID ON DNA CONTENT ALTERATIONS CAUSED BY PROFENOFOS IN LAMELLIDENS MARGINALIS (LAMARCK). International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2025 [Cited : ]; 11(3) : 2907-2914. Available from: http://ijariie.com/AdminUploadPdf/MITIGATING_EFFECT_OF_L_ASCORBIC_ACID_ON_DNA_CONTENT_ALTERATIONS_CAUSED_BY_PROFENOFOS_IN_LAMELLIDENS_MARGINALIS__LAMARCK__ijariie26839.pdf
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