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Title: :  DESIGN AND DEVELOPMENT OF POLYMERIC NANOPARTICLES LOADED IN HYDROGEL OF MICONAZOLE FOR FUNGAL TREATMENT
PaperId: :  27698
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 11 Issue 6 2025
DUI:    16.0415/IJARIIE-27698
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Shivam GuptaDaksh Institute of Pharmaceutical Science, Chhatarpur (MP)
Shailendra ModiDaksh Institute of Pharmaceutical Science, Chhatarpur (MP)
Vijay NigamDaksh Institute of Pharmaceutical Science, Chhatarpur (MP)
Ashish NigamDaksh Institute of Pharmaceutical Science, Chhatarpur (MP)

Abstract

Pharmaceutical
Viscosity, Evaluation, Drug, Gel, Spreadability.
Miconazole is one of the broad spectrum antifungal compounds of the imidazole group. In Present investigation chiosan nanoparticles of Miconazole was prepared and evaluated for Percentage yield, Drug entrapment, Zeta potential and particle size and further prepared nanoparticles incorporated in gel base and evaluated. Percentage yield of different formulation was determined by weighing the nanoparticles after drying. The optimized formulation among other batches subjected to further studies.The results of measurement of mean particle size of optimized formulation F2 nanoparticles were found 85.6 nm. Gel preparation corresponding to 2.0% w/w (2.0 mgof drug in 100 mg of gel) of drug was incorporated into the gel base to get the desired concentration of drug in gel base.Gels were evaluated by means of pH, spreadability, viscosity and drug content and extrudability. pH was determined using digital pH meter.The viscosity of gels was determined by using a Brookfield viscometer DV-II model. It was concluded that prepared gel containing Miconazole nanoparticles was optimized and successfully formulated in the form gel can be use for topical preparation for antifungal effect.

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IJARIIE Shivam Gupta, Shailendra Modi, Vijay Nigam, and Ashish Nigam. "DESIGN AND DEVELOPMENT OF POLYMERIC NANOPARTICLES LOADED IN HYDROGEL OF MICONAZOLE FOR FUNGAL TREATMENT" International Journal Of Advance Research And Innovative Ideas In Education Volume 11 Issue 6 2025 Page 550-557
MLA Shivam Gupta, Shailendra Modi, Vijay Nigam, and Ashish Nigam. "DESIGN AND DEVELOPMENT OF POLYMERIC NANOPARTICLES LOADED IN HYDROGEL OF MICONAZOLE FOR FUNGAL TREATMENT." International Journal Of Advance Research And Innovative Ideas In Education 11.6(2025) : 550-557.
APA Shivam Gupta, Shailendra Modi, Vijay Nigam, & Ashish Nigam. (2025). DESIGN AND DEVELOPMENT OF POLYMERIC NANOPARTICLES LOADED IN HYDROGEL OF MICONAZOLE FOR FUNGAL TREATMENT. International Journal Of Advance Research And Innovative Ideas In Education, 11(6), 550-557.
Chicago Shivam Gupta, Shailendra Modi, Vijay Nigam, and Ashish Nigam. "DESIGN AND DEVELOPMENT OF POLYMERIC NANOPARTICLES LOADED IN HYDROGEL OF MICONAZOLE FOR FUNGAL TREATMENT." International Journal Of Advance Research And Innovative Ideas In Education 11, no. 6 (2025) : 550-557.
Oxford Shivam Gupta, Shailendra Modi, Vijay Nigam, and Ashish Nigam. 'DESIGN AND DEVELOPMENT OF POLYMERIC NANOPARTICLES LOADED IN HYDROGEL OF MICONAZOLE FOR FUNGAL TREATMENT', International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 6, 2025, p. 550-557. Available from IJARIIE, http://ijariie.com/AdminUploadPdf/DESIGN_AND_DEVELOPMENT_OF_POLYMERIC_NANOPARTICLES_LOADED_IN_HYDROGEL_OF_MICONAZOLE_FOR_FUNGAL_TREATMENT_ijariie27698.pdf (Accessed : 19 November 2025).
Harvard Shivam Gupta, Shailendra Modi, Vijay Nigam, and Ashish Nigam. (2025) 'DESIGN AND DEVELOPMENT OF POLYMERIC NANOPARTICLES LOADED IN HYDROGEL OF MICONAZOLE FOR FUNGAL TREATMENT', International Journal Of Advance Research And Innovative Ideas In Education, 11(6), pp. 550-557IJARIIE [Online]. Available at: http://ijariie.com/AdminUploadPdf/DESIGN_AND_DEVELOPMENT_OF_POLYMERIC_NANOPARTICLES_LOADED_IN_HYDROGEL_OF_MICONAZOLE_FOR_FUNGAL_TREATMENT_ijariie27698.pdf (Accessed : 19 November 2025)
IEEE Shivam Gupta, Shailendra Modi, Vijay Nigam, and Ashish Nigam, "DESIGN AND DEVELOPMENT OF POLYMERIC NANOPARTICLES LOADED IN HYDROGEL OF MICONAZOLE FOR FUNGAL TREATMENT," International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 6, pp. 550-557, Nov-Dec 2025. [Online]. Available: http://ijariie.com/AdminUploadPdf/DESIGN_AND_DEVELOPMENT_OF_POLYMERIC_NANOPARTICLES_LOADED_IN_HYDROGEL_OF_MICONAZOLE_FOR_FUNGAL_TREATMENT_ijariie27698.pdf [Accessed : 19 November 2025].
Turabian Shivam Gupta, Shailendra Modi, Vijay Nigam, and Ashish Nigam. "DESIGN AND DEVELOPMENT OF POLYMERIC NANOPARTICLES LOADED IN HYDROGEL OF MICONAZOLE FOR FUNGAL TREATMENT." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 11 number 6 (19 November 2025).
Vancouver Shivam Gupta, Shailendra Modi, Vijay Nigam, and Ashish Nigam. DESIGN AND DEVELOPMENT OF POLYMERIC NANOPARTICLES LOADED IN HYDROGEL OF MICONAZOLE FOR FUNGAL TREATMENT. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2025 [Cited : 19 November 2025]; 11(6) : 550-557. Available from: http://ijariie.com/AdminUploadPdf/DESIGN_AND_DEVELOPMENT_OF_POLYMERIC_NANOPARTICLES_LOADED_IN_HYDROGEL_OF_MICONAZOLE_FOR_FUNGAL_TREATMENT_ijariie27698.pdf
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