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Title: :  DEVELOPMENT AND VALIDATED UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF FIMASARTAN IN PURE AND PHARMACEUTICAL DOSAGE FORMS
PaperId: :  10754
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 5 Issue 4 2019
DUI:    16.0415/IJARIIE-10754
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
SHAHEEM SULTHANA MOHAMMADASN PHARMACY COLLEGE
SRI LAKSHMI AVUTUASN PHARMACY COLLEGE
JHANSI LAKSHMI MARREDDYASN PHARMACY COLLEGE

Abstract

Pharmaceutical analysis
Key words: Fimasartan, Method development, UV spectroscopy.
A simple, precise, accurate, cost effective stability indicating UV- spectrophotometric method has been developed for the estimation of Fimasartan in bulk and tablet dosage form. Fimasartan shows highest λmax at 261 nm. Beer's law (linearity response) was found over a concentration range of 10-50 μg /mL with good correlation coefficient (r2 = 0.999). The detection limit (DL) & quantitation limit (QL) were found to be 0.002 mcg/mL and 0.001 mcg/mL respectively. The results of the Fimasartan recovery analysis were found to be 96.80±0.001 to 98.28±0.002. Percentage assay of Fimasartan tablets (Fimanta) got more than 99.96 %. The proposed spectrophotometric method was validated as per the ICH Q1A (R2) guidelines. While estimating the Fimasartan in tablet formulation, there was no interference of additives & excipients. Hence this method can be safely being employed for the routine quality control analysis of Fimasartan in bulk and tablet dosage form.

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IJARIIE SHAHEEM SULTHANA MOHAMMAD, SRI LAKSHMI AVUTU, and JHANSI LAKSHMI MARREDDY. "DEVELOPMENT AND VALIDATED UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF FIMASARTAN IN PURE AND PHARMACEUTICAL DOSAGE FORMS" International Journal Of Advance Research And Innovative Ideas In Education Volume 5 Issue 4 2019 Page 1410-1417
MLA SHAHEEM SULTHANA MOHAMMAD, SRI LAKSHMI AVUTU, and JHANSI LAKSHMI MARREDDY. "DEVELOPMENT AND VALIDATED UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF FIMASARTAN IN PURE AND PHARMACEUTICAL DOSAGE FORMS." International Journal Of Advance Research And Innovative Ideas In Education 5.4(2019) : 1410-1417.
APA SHAHEEM SULTHANA MOHAMMAD, SRI LAKSHMI AVUTU, & JHANSI LAKSHMI MARREDDY. (2019). DEVELOPMENT AND VALIDATED UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF FIMASARTAN IN PURE AND PHARMACEUTICAL DOSAGE FORMS. International Journal Of Advance Research And Innovative Ideas In Education, 5(4), 1410-1417.
Chicago SHAHEEM SULTHANA MOHAMMAD, SRI LAKSHMI AVUTU, and JHANSI LAKSHMI MARREDDY. "DEVELOPMENT AND VALIDATED UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF FIMASARTAN IN PURE AND PHARMACEUTICAL DOSAGE FORMS." International Journal Of Advance Research And Innovative Ideas In Education 5, no. 4 (2019) : 1410-1417.
Oxford SHAHEEM SULTHANA MOHAMMAD, SRI LAKSHMI AVUTU, and JHANSI LAKSHMI MARREDDY. 'DEVELOPMENT AND VALIDATED UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF FIMASARTAN IN PURE AND PHARMACEUTICAL DOSAGE FORMS', International Journal Of Advance Research And Innovative Ideas In Education, vol. 5, no. 4, 2019, p. 1410-1417. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_VALIDATED_UV_SPECTROPHOTOMETRIC_METHOD_FOR_THE_ESTIMATION_OF_FIMASARTAN_IN_PURE_AND_PHARMACEUTICAL_DOSAGE_FORMS_ijariie10754.pdf (Accessed : ).
Harvard SHAHEEM SULTHANA MOHAMMAD, SRI LAKSHMI AVUTU, and JHANSI LAKSHMI MARREDDY. (2019) 'DEVELOPMENT AND VALIDATED UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF FIMASARTAN IN PURE AND PHARMACEUTICAL DOSAGE FORMS', International Journal Of Advance Research And Innovative Ideas In Education, 5(4), pp. 1410-1417IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_VALIDATED_UV_SPECTROPHOTOMETRIC_METHOD_FOR_THE_ESTIMATION_OF_FIMASARTAN_IN_PURE_AND_PHARMACEUTICAL_DOSAGE_FORMS_ijariie10754.pdf (Accessed : )
IEEE SHAHEEM SULTHANA MOHAMMAD, SRI LAKSHMI AVUTU, and JHANSI LAKSHMI MARREDDY, "DEVELOPMENT AND VALIDATED UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF FIMASARTAN IN PURE AND PHARMACEUTICAL DOSAGE FORMS," International Journal Of Advance Research And Innovative Ideas In Education, vol. 5, no. 4, pp. 1410-1417, Jul-Aug 2019. [Online]. Available: https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_VALIDATED_UV_SPECTROPHOTOMETRIC_METHOD_FOR_THE_ESTIMATION_OF_FIMASARTAN_IN_PURE_AND_PHARMACEUTICAL_DOSAGE_FORMS_ijariie10754.pdf [Accessed : ].
Turabian SHAHEEM SULTHANA MOHAMMAD, SRI LAKSHMI AVUTU, and JHANSI LAKSHMI MARREDDY. "DEVELOPMENT AND VALIDATED UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF FIMASARTAN IN PURE AND PHARMACEUTICAL DOSAGE FORMS." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 5 number 4 ().
Vancouver SHAHEEM SULTHANA MOHAMMAD, SRI LAKSHMI AVUTU, and JHANSI LAKSHMI MARREDDY. DEVELOPMENT AND VALIDATED UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF FIMASARTAN IN PURE AND PHARMACEUTICAL DOSAGE FORMS. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2019 [Cited : ]; 5(4) : 1410-1417. Available from: https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_VALIDATED_UV_SPECTROPHOTOMETRIC_METHOD_FOR_THE_ESTIMATION_OF_FIMASARTAN_IN_PURE_AND_PHARMACEUTICAL_DOSAGE_FORMS_ijariie10754.pdf
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