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Title: :  STABILITY INDICATING DETERMINATION OF VALACYCLOVIR BY RP-HPLC METHOD
PaperId: :  12017
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 6 Issue 3 2020
DUI:    16.0415/IJARIIE-12017
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Dr. Juluri Krishna Dutta TejaswiJogaiah College of Pharmacy

Abstract

PHARMACY
Valacyclovir, Acyclovir, Prodrug, Valcivir.
A simple Stability indicating reverse phase HPLC method was developed for the determination of Valacyclovir present in pharmaceutical dosage forms. Valacyclovir represents a clear advance in the prevention and treatment of viral infection.The mobile phase was simple to prepare and economical. A Hypersil ODS C-18 (250 x 4.6 mm, packed with 5 micron) in an isocratic mode with mobile phase Acetonitrile: Phosphate buffer (pH- 3.6) (50:50%v/v) was used. The flow rate was 0.8ml/ min and effluent was monitored at 252 nm. The retention time was 2.842 min Valacyclovir. The linearity range was found to be 0.5 - 200 mg/ml. It was found that the percentage recovery values of pure drug from the pre-analyzed solutions of formulations were in between 98.1337- 101.4633. All the degradation products formed during forced decomposition studies were well separated from the analyte peak demonstrates that the developed method was specific and stability-indicating.

Citations

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IJARIIE Dr. Juluri Krishna Dutta Tejaswi. "STABILITY INDICATING DETERMINATION OF VALACYCLOVIR BY RP-HPLC METHOD" International Journal Of Advance Research And Innovative Ideas In Education Volume 6 Issue 3 2020 Page 526-532
MLA Dr. Juluri Krishna Dutta Tejaswi. "STABILITY INDICATING DETERMINATION OF VALACYCLOVIR BY RP-HPLC METHOD." International Journal Of Advance Research And Innovative Ideas In Education 6.3(2020) : 526-532.
APA Dr. Juluri Krishna Dutta Tejaswi. (2020). STABILITY INDICATING DETERMINATION OF VALACYCLOVIR BY RP-HPLC METHOD. International Journal Of Advance Research And Innovative Ideas In Education, 6(3), 526-532.
Chicago Dr. Juluri Krishna Dutta Tejaswi. "STABILITY INDICATING DETERMINATION OF VALACYCLOVIR BY RP-HPLC METHOD." International Journal Of Advance Research And Innovative Ideas In Education 6, no. 3 (2020) : 526-532.
Oxford Dr. Juluri Krishna Dutta Tejaswi. 'STABILITY INDICATING DETERMINATION OF VALACYCLOVIR BY RP-HPLC METHOD', International Journal Of Advance Research And Innovative Ideas In Education, vol. 6, no. 3, 2020, p. 526-532. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/STABILITY_INDICATING_DETERMINATION_OF_VALACYCLOVIR_BY_RP_HPLC_METHOD_ijariie12017.pdf (Accessed : 25 May 2020).
Harvard Dr. Juluri Krishna Dutta Tejaswi. (2020) 'STABILITY INDICATING DETERMINATION OF VALACYCLOVIR BY RP-HPLC METHOD', International Journal Of Advance Research And Innovative Ideas In Education, 6(3), pp. 526-532IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/STABILITY_INDICATING_DETERMINATION_OF_VALACYCLOVIR_BY_RP_HPLC_METHOD_ijariie12017.pdf (Accessed : 25 May 2020)
IEEE Dr. Juluri Krishna Dutta Tejaswi, "STABILITY INDICATING DETERMINATION OF VALACYCLOVIR BY RP-HPLC METHOD," International Journal Of Advance Research And Innovative Ideas In Education, vol. 6, no. 3, pp. 526-532, May-Jun 2020. [Online]. Available: https://ijariie.com/AdminUploadPdf/STABILITY_INDICATING_DETERMINATION_OF_VALACYCLOVIR_BY_RP_HPLC_METHOD_ijariie12017.pdf [Accessed : 25 May 2020].
Turabian Dr. Juluri Krishna Dutta Tejaswi. "STABILITY INDICATING DETERMINATION OF VALACYCLOVIR BY RP-HPLC METHOD." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 6 number 3 (25 May 2020).
Vancouver Dr. Juluri Krishna Dutta Tejaswi. STABILITY INDICATING DETERMINATION OF VALACYCLOVIR BY RP-HPLC METHOD. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2020 [Cited : 25 May 2020]; 6(3) : 526-532. Available from: https://ijariie.com/AdminUploadPdf/STABILITY_INDICATING_DETERMINATION_OF_VALACYCLOVIR_BY_RP_HPLC_METHOD_ijariie12017.pdf
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