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Title: :  The effects of Arsenite on learning and memory Caenorhabditis elegans
PaperId: :  12786
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 6 Issue 5 2020
DUI:    16.0415/IJARIIE-12786
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Vishwanth KumarStudent, Centre for Biological Sciences, Central University of South Bihar, Bihar, India
Jai Prakash SinghStudent, Centre for Biological Sciences, Central University of South Bihar, Bihar, India
Sukanya KumariStudent, Department of Education in Science & Mathematics, Regional Institute of Education, Bhubaneshwar, Odisha, India

Abstract

Life science
C. elegans, Neurotoxic Metals, Caenorhabditis elegans, and Arsenic Toxicity
The nematode Caenorhabditis elegans has emerged as an important animal model in various fields including neurobiology, developmental biology, and genetics. Characteristics of this animal model that have contributed to its success include its genetic manipulability, invariant and fully described developmental program, well-characterized genome, ease of maintenance, short and prolific life cycle, and small body size. These same features have led to an increasing use of C. elegans in toxicology, both for mechanistic studies and high-throughput screening approaches. We describe some of the research that has been carried out in the areas of neurotoxicology, genetic toxicology, and environmental toxicology, as well as high-throughput experiments with C. elegans including genome-wide screening for molecular targets of toxicity and rapid toxicity assessment for new chemicals. We argue for an increased role for C. elegans in complementing other model systems in toxicological research. Years before the latest technologic developments (RNAi and high-throughput techniques), C. elegans was used to study toxicity mechanisms of environmental factors affecting the nervous system. The following section provides a synopsis of the available literature on neurotoxicity-related issues addressed in C. elegans. It is not meant to be exhaustive but rather to illustrate typical studies that are amenable in the C. elegans platform. We highlight studies with exposure outcomes to various metals and pesticides, as well as general considerations on studies of neurodegenerative diseases. We emphasize the utility of C. elegans in addressing hypothesis-driven mechanisms of neurotoxicity and extrapolations to vertebrate systems.

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IJARIIE Vishwanth Kumar, Jai Prakash Singh, and Sukanya Kumari. "The effects of Arsenite on learning and memory Caenorhabditis elegans" International Journal Of Advance Research And Innovative Ideas In Education Volume 6 Issue 5 2020 Page 987-995
MLA Vishwanth Kumar, Jai Prakash Singh, and Sukanya Kumari. "The effects of Arsenite on learning and memory Caenorhabditis elegans." International Journal Of Advance Research And Innovative Ideas In Education 6.5(2020) : 987-995.
APA Vishwanth Kumar, Jai Prakash Singh, & Sukanya Kumari. (2020). The effects of Arsenite on learning and memory Caenorhabditis elegans. International Journal Of Advance Research And Innovative Ideas In Education, 6(5), 987-995.
Chicago Vishwanth Kumar, Jai Prakash Singh, and Sukanya Kumari. "The effects of Arsenite on learning and memory Caenorhabditis elegans." International Journal Of Advance Research And Innovative Ideas In Education 6, no. 5 (2020) : 987-995.
Oxford Vishwanth Kumar, Jai Prakash Singh, and Sukanya Kumari. 'The effects of Arsenite on learning and memory Caenorhabditis elegans', International Journal Of Advance Research And Innovative Ideas In Education, vol. 6, no. 5, 2020, p. 987-995. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/The_effects_of_Arsenite_on_learning_and_memory_Caenorhabditis_elegans_ijariie12786.pdf (Accessed : ).
Harvard Vishwanth Kumar, Jai Prakash Singh, and Sukanya Kumari. (2020) 'The effects of Arsenite on learning and memory Caenorhabditis elegans', International Journal Of Advance Research And Innovative Ideas In Education, 6(5), pp. 987-995IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/The_effects_of_Arsenite_on_learning_and_memory_Caenorhabditis_elegans_ijariie12786.pdf (Accessed : )
IEEE Vishwanth Kumar, Jai Prakash Singh, and Sukanya Kumari, "The effects of Arsenite on learning and memory Caenorhabditis elegans," International Journal Of Advance Research And Innovative Ideas In Education, vol. 6, no. 5, pp. 987-995, Sep-Oct 2020. [Online]. Available: https://ijariie.com/AdminUploadPdf/The_effects_of_Arsenite_on_learning_and_memory_Caenorhabditis_elegans_ijariie12786.pdf [Accessed : ].
Turabian Vishwanth Kumar, Jai Prakash Singh, and Sukanya Kumari. "The effects of Arsenite on learning and memory Caenorhabditis elegans." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 6 number 5 ().
Vancouver Vishwanth Kumar, Jai Prakash Singh, and Sukanya Kumari. The effects of Arsenite on learning and memory Caenorhabditis elegans. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2020 [Cited : ]; 6(5) : 987-995. Available from: https://ijariie.com/AdminUploadPdf/The_effects_of_Arsenite_on_learning_and_memory_Caenorhabditis_elegans_ijariie12786.pdf
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