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Title: :  EVALUATION OF ANTIDIABETIC ACTION OF ARAUCARIA COLUMNARIS LEAF EXTRACTS
PaperId: :  12866
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 6 Issue 5 2020
DUI:    16.0415/IJARIIE-12866
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Devendra Kumar rawatSchool of Pharmacy, LNCT University, Bhopal, Madhya Pradesh
Vishal ShrivastavaSchool of Pharmacy, LNCT University, Bhopal, Madhya Pradesh
Kehar Singh DhakadSchool of Pharmacy, LNCT University, Bhopal, Madhya Pradesh
Arun Kumar SharmaSchool of Pharmacy, LNCT University, Bhopal, Madhya Pradesh

Abstract

Pharmacy
Araucaria Columnaris; Alloxan induced diabetic model; Antidiabetic; Wistar Rat.
The leaf bearing branchlets are narrow at the petiole, broaden towards the middle and narrow down towards the apex. The ability of different solvents to extract phytochemicals from leaves followed the order: methanol>water>ethyl acetate>benzene. The preliminary qualitative phytochemical analysis suggests the presence of saponin glycosides, cardiac glycosides, phenolics, terpenoids, sterols, and flavonoids in the leaves. The total phenolic content of benzene, ethyl acetate, methanolic and aqueous extract of Araucaria columnaris were 5.18±0.91, 8.97±0.17, 63.22±0.48 and 38.24±0.63 GAE mg/g, respectively. All the extracts were subjected to in vitro determination of antioxidant potential using DPPH scavenging method. The IC50 value of the DPPH scavenging potential for benzene and ethyl acetate was found to be more than 250µg/mL whereas for methanol and aqueous extracts was found to be 136.6 and 200.2 µg/mL respectively. Alloxan induced diabetes model was used for determining the antidiabetic potential of the methanolic and aqueous extracts. The aqueous extract was able to lower the blood glucose more in comparison to the methanolic extract comparable to the standard drug glibenclamide.

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IJARIIE Devendra Kumar rawat, Vishal Shrivastava, Kehar Singh Dhakad, and Arun Kumar Sharma. "EVALUATION OF ANTIDIABETIC ACTION OF ARAUCARIA COLUMNARIS LEAF EXTRACTS" International Journal Of Advance Research And Innovative Ideas In Education Volume 6 Issue 5 2020 Page 1367-1372
MLA Devendra Kumar rawat, Vishal Shrivastava, Kehar Singh Dhakad, and Arun Kumar Sharma. "EVALUATION OF ANTIDIABETIC ACTION OF ARAUCARIA COLUMNARIS LEAF EXTRACTS." International Journal Of Advance Research And Innovative Ideas In Education 6.5(2020) : 1367-1372.
APA Devendra Kumar rawat, Vishal Shrivastava, Kehar Singh Dhakad, & Arun Kumar Sharma. (2020). EVALUATION OF ANTIDIABETIC ACTION OF ARAUCARIA COLUMNARIS LEAF EXTRACTS. International Journal Of Advance Research And Innovative Ideas In Education, 6(5), 1367-1372.
Chicago Devendra Kumar rawat, Vishal Shrivastava, Kehar Singh Dhakad, and Arun Kumar Sharma. "EVALUATION OF ANTIDIABETIC ACTION OF ARAUCARIA COLUMNARIS LEAF EXTRACTS." International Journal Of Advance Research And Innovative Ideas In Education 6, no. 5 (2020) : 1367-1372.
Oxford Devendra Kumar rawat, Vishal Shrivastava, Kehar Singh Dhakad, and Arun Kumar Sharma. 'EVALUATION OF ANTIDIABETIC ACTION OF ARAUCARIA COLUMNARIS LEAF EXTRACTS', International Journal Of Advance Research And Innovative Ideas In Education, vol. 6, no. 5, 2020, p. 1367-1372. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/EVALUATION_OF_ANTIDIABETIC_ACTION_OF_ARAUCARIA_COLUMNARIS_LEAF_EXTRACTS_ijariie12866.pdf (Accessed : 09 October 2020).
Harvard Devendra Kumar rawat, Vishal Shrivastava, Kehar Singh Dhakad, and Arun Kumar Sharma. (2020) 'EVALUATION OF ANTIDIABETIC ACTION OF ARAUCARIA COLUMNARIS LEAF EXTRACTS', International Journal Of Advance Research And Innovative Ideas In Education, 6(5), pp. 1367-1372IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/EVALUATION_OF_ANTIDIABETIC_ACTION_OF_ARAUCARIA_COLUMNARIS_LEAF_EXTRACTS_ijariie12866.pdf (Accessed : 09 October 2020)
IEEE Devendra Kumar rawat, Vishal Shrivastava, Kehar Singh Dhakad, and Arun Kumar Sharma, "EVALUATION OF ANTIDIABETIC ACTION OF ARAUCARIA COLUMNARIS LEAF EXTRACTS," International Journal Of Advance Research And Innovative Ideas In Education, vol. 6, no. 5, pp. 1367-1372, Sep-Oct 2020. [Online]. Available: https://ijariie.com/AdminUploadPdf/EVALUATION_OF_ANTIDIABETIC_ACTION_OF_ARAUCARIA_COLUMNARIS_LEAF_EXTRACTS_ijariie12866.pdf [Accessed : 09 October 2020].
Turabian Devendra Kumar rawat, Vishal Shrivastava, Kehar Singh Dhakad, and Arun Kumar Sharma. "EVALUATION OF ANTIDIABETIC ACTION OF ARAUCARIA COLUMNARIS LEAF EXTRACTS." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 6 number 5 (09 October 2020).
Vancouver Devendra Kumar rawat, Vishal Shrivastava, Kehar Singh Dhakad, and Arun Kumar Sharma. EVALUATION OF ANTIDIABETIC ACTION OF ARAUCARIA COLUMNARIS LEAF EXTRACTS. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2020 [Cited : 09 October 2020]; 6(5) : 1367-1372. Available from: https://ijariie.com/AdminUploadPdf/EVALUATION_OF_ANTIDIABETIC_ACTION_OF_ARAUCARIA_COLUMNARIS_LEAF_EXTRACTS_ijariie12866.pdf
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