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Title: :  EVALUATION OF CNS STIMULANT POTENTIAL OF DELONIX REGIA LEAF EXTRACTS
PaperId: :  12912
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 6 Issue 5 2020
DUI:    16.0415/IJARIIE-12912
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Asif AtaSchool of Pharmacy, LNCT University, Bhopal, Madhya Pradesh
Dr. Parul MehtaSchool of Pharmacy, LNCT University, Bhopal, Madhya Pradesh
Vishal ShrivastavaSchool of Pharmacy, LNCT University, Bhopal, Madhya Pradesh
Kehar Singh DhakadSchool of Pharmacy, LNCT University, Bhopal, Madhya Pradesh

Abstract

Pharmacology
Delonix Regia; CNS Stimulant Potential; Photoactometer recognizable locomotion test, Mice.
The leaves of Delonix regia grow alternately on the stem, biparpipinnate with stout petiole. The extraction ability of different solvents for recovering extractable components from leaves followed the order: methanol>ethylacetate>water>n-hexane. The findings of preliminary phytochemical analysis suggest the presence of alkaloids, saponin glycosides, phenolics, terpenoids, sterols, and flavonoids in the leaf of the plant. All the extracts were subjected to in vivo determination of CNS stimulant potential using photoactometer recognizable locomotion test and tail suspension test to evaluate the behavior of the mice. The results reveal that all the extracts except nhexane extracted component was able to increase the locomotion in mice significantly (p<0.05) as evidenced by actophotometer test. The ethanolic extract exhibited better CNS stimulation compared to the standard drug caffeine at a dose of 200 mg/kg per oral. From the results that immobilization time of the ethanolic extract was comparable at both the evaluated doses was comparable to that of caffeine while the ethylacetate and aqueous extracts were able to reduce the immobility time by a lower margin compared to the control group. The n-hexane extract was unable to reduce the immobilization time in mice. Diazepam was used as the negative control to monitor immobility and lack of locomotor response while caffeine was used as the reference drug to compare the CNS stimulant potential

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IJARIIE Asif Ata, Dr. Parul Mehta, Vishal Shrivastava, and Kehar Singh Dhakad. "EVALUATION OF CNS STIMULANT POTENTIAL OF DELONIX REGIA LEAF EXTRACTS" International Journal Of Advance Research And Innovative Ideas In Education Volume 6 Issue 5 2020 Page 1657-1661
MLA Asif Ata, Dr. Parul Mehta, Vishal Shrivastava, and Kehar Singh Dhakad. "EVALUATION OF CNS STIMULANT POTENTIAL OF DELONIX REGIA LEAF EXTRACTS." International Journal Of Advance Research And Innovative Ideas In Education 6.5(2020) : 1657-1661.
APA Asif Ata, Dr. Parul Mehta, Vishal Shrivastava, & Kehar Singh Dhakad. (2020). EVALUATION OF CNS STIMULANT POTENTIAL OF DELONIX REGIA LEAF EXTRACTS. International Journal Of Advance Research And Innovative Ideas In Education, 6(5), 1657-1661.
Chicago Asif Ata, Dr. Parul Mehta, Vishal Shrivastava, and Kehar Singh Dhakad. "EVALUATION OF CNS STIMULANT POTENTIAL OF DELONIX REGIA LEAF EXTRACTS." International Journal Of Advance Research And Innovative Ideas In Education 6, no. 5 (2020) : 1657-1661.
Oxford Asif Ata, Dr. Parul Mehta, Vishal Shrivastava, and Kehar Singh Dhakad. 'EVALUATION OF CNS STIMULANT POTENTIAL OF DELONIX REGIA LEAF EXTRACTS', International Journal Of Advance Research And Innovative Ideas In Education, vol. 6, no. 5, 2020, p. 1657-1661. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/EVALUATION_OF_CNS_STIMULANT_POTENTIAL_OF_DELONIX_REGIA_LEAF_EXTRACTS_ijariie12912.pdf (Accessed : ).
Harvard Asif Ata, Dr. Parul Mehta, Vishal Shrivastava, and Kehar Singh Dhakad. (2020) 'EVALUATION OF CNS STIMULANT POTENTIAL OF DELONIX REGIA LEAF EXTRACTS', International Journal Of Advance Research And Innovative Ideas In Education, 6(5), pp. 1657-1661IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/EVALUATION_OF_CNS_STIMULANT_POTENTIAL_OF_DELONIX_REGIA_LEAF_EXTRACTS_ijariie12912.pdf (Accessed : )
IEEE Asif Ata, Dr. Parul Mehta, Vishal Shrivastava, and Kehar Singh Dhakad, "EVALUATION OF CNS STIMULANT POTENTIAL OF DELONIX REGIA LEAF EXTRACTS," International Journal Of Advance Research And Innovative Ideas In Education, vol. 6, no. 5, pp. 1657-1661, Sep-Oct 2020. [Online]. Available: https://ijariie.com/AdminUploadPdf/EVALUATION_OF_CNS_STIMULANT_POTENTIAL_OF_DELONIX_REGIA_LEAF_EXTRACTS_ijariie12912.pdf [Accessed : ].
Turabian Asif Ata, Dr. Parul Mehta, Vishal Shrivastava, and Kehar Singh Dhakad. "EVALUATION OF CNS STIMULANT POTENTIAL OF DELONIX REGIA LEAF EXTRACTS." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 6 number 5 ().
Vancouver Asif Ata, Dr. Parul Mehta, Vishal Shrivastava, and Kehar Singh Dhakad. EVALUATION OF CNS STIMULANT POTENTIAL OF DELONIX REGIA LEAF EXTRACTS. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2020 [Cited : ]; 6(5) : 1657-1661. Available from: https://ijariie.com/AdminUploadPdf/EVALUATION_OF_CNS_STIMULANT_POTENTIAL_OF_DELONIX_REGIA_LEAF_EXTRACTS_ijariie12912.pdf
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