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Title: :  FORMULATION AND EVALUATION OF EXTENDED RELEASE MATRIX TABLETS OF AZILSARTAN USING NATURAL AND SYNTHETIC POLYMERS
PaperId: :  13352
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 6 Issue 6 2020
DUI:    16.0415/IJARIIE-13352
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
K.tarunikaAVNATHI INSTITUTE OF PHARMACEUTICAL SCIENCES
Dr.RAMA KRISHNA MUNGIAVNATHI INSTITUTE OF PHARMACEUTICAL SCIENCES

Abstract

Pharmacy
Azilsartan, Locust Bean gum, Chitosasn, HPMC, Extended release tablets.
The aim of the present study was to develop extended release formulation of azilsartan to maintain constant therapeutic levels of the drug for over 12 hrs. Azilsartan is an angiotensin II receptor antagonist used in the treatment of hypertension. Locust Bean gum, Chitosan and HPMC K15M were employed as polymers. Preformulations studies were carried out for all the parameters such as angle of repose, bulk density, tapped density and Hausners ratio were found to be good. Drug and excipient compatability studies were carried out using FTIR and DSC, based on the results the it was found that there were no interactions. Various quality control evaluation parameters were carried out and the results were found to be good.Whereas from the dissolution studies it was evident that the formulation (F10) showed better and desired drug release pattern i.e., 99.75% in 12 hours. It contains the natural polymer HPMC K15M as extended release material. It followed peppas release kinetics mechanism.

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IJARIIE K.tarunika, and Dr.RAMA KRISHNA MUNGI. "FORMULATION AND EVALUATION OF EXTENDED RELEASE MATRIX TABLETS OF AZILSARTAN USING NATURAL AND SYNTHETIC POLYMERS" International Journal Of Advance Research And Innovative Ideas In Education Volume 6 Issue 6 2020 Page 2388-2401
MLA K.tarunika, and Dr.RAMA KRISHNA MUNGI. "FORMULATION AND EVALUATION OF EXTENDED RELEASE MATRIX TABLETS OF AZILSARTAN USING NATURAL AND SYNTHETIC POLYMERS." International Journal Of Advance Research And Innovative Ideas In Education 6.6(2020) : 2388-2401.
APA K.tarunika, & Dr.RAMA KRISHNA MUNGI. (2020). FORMULATION AND EVALUATION OF EXTENDED RELEASE MATRIX TABLETS OF AZILSARTAN USING NATURAL AND SYNTHETIC POLYMERS. International Journal Of Advance Research And Innovative Ideas In Education, 6(6), 2388-2401.
Chicago K.tarunika, and Dr.RAMA KRISHNA MUNGI. "FORMULATION AND EVALUATION OF EXTENDED RELEASE MATRIX TABLETS OF AZILSARTAN USING NATURAL AND SYNTHETIC POLYMERS." International Journal Of Advance Research And Innovative Ideas In Education 6, no. 6 (2020) : 2388-2401.
Oxford K.tarunika, and Dr.RAMA KRISHNA MUNGI. 'FORMULATION AND EVALUATION OF EXTENDED RELEASE MATRIX TABLETS OF AZILSARTAN USING NATURAL AND SYNTHETIC POLYMERS', International Journal Of Advance Research And Innovative Ideas In Education, vol. 6, no. 6, 2020, p. 2388-2401. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/FORMULATION_AND_EVALUATION_OF_EXTENDED_RELEASE_MATRIX_TABLETS_OF_AZILSARTAN_USING_NATURAL_AND_SYNTHETIC_POLYMERS_ijariie13352.pdf (Accessed : ).
Harvard K.tarunika, and Dr.RAMA KRISHNA MUNGI. (2020) 'FORMULATION AND EVALUATION OF EXTENDED RELEASE MATRIX TABLETS OF AZILSARTAN USING NATURAL AND SYNTHETIC POLYMERS', International Journal Of Advance Research And Innovative Ideas In Education, 6(6), pp. 2388-2401IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/FORMULATION_AND_EVALUATION_OF_EXTENDED_RELEASE_MATRIX_TABLETS_OF_AZILSARTAN_USING_NATURAL_AND_SYNTHETIC_POLYMERS_ijariie13352.pdf (Accessed : )
IEEE K.tarunika, and Dr.RAMA KRISHNA MUNGI, "FORMULATION AND EVALUATION OF EXTENDED RELEASE MATRIX TABLETS OF AZILSARTAN USING NATURAL AND SYNTHETIC POLYMERS," International Journal Of Advance Research And Innovative Ideas In Education, vol. 6, no. 6, pp. 2388-2401, Nov-Dec 2020. [Online]. Available: https://ijariie.com/AdminUploadPdf/FORMULATION_AND_EVALUATION_OF_EXTENDED_RELEASE_MATRIX_TABLETS_OF_AZILSARTAN_USING_NATURAL_AND_SYNTHETIC_POLYMERS_ijariie13352.pdf [Accessed : ].
Turabian K.tarunika, and Dr.RAMA KRISHNA MUNGI. "FORMULATION AND EVALUATION OF EXTENDED RELEASE MATRIX TABLETS OF AZILSARTAN USING NATURAL AND SYNTHETIC POLYMERS." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 6 number 6 ().
Vancouver K.tarunika, and Dr.RAMA KRISHNA MUNGI. FORMULATION AND EVALUATION OF EXTENDED RELEASE MATRIX TABLETS OF AZILSARTAN USING NATURAL AND SYNTHETIC POLYMERS. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2020 [Cited : ]; 6(6) : 2388-2401. Available from: https://ijariie.com/AdminUploadPdf/FORMULATION_AND_EVALUATION_OF_EXTENDED_RELEASE_MATRIX_TABLETS_OF_AZILSARTAN_USING_NATURAL_AND_SYNTHETIC_POLYMERS_ijariie13352.pdf
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