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Call for Papers:Vol.11 Issue.3

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Title: :  FORMULATION DEVELOPMENT AND EVALUATION OF pH BASED INSITU VAGINAL GEL OF SECNIDAZOLE for vaginal delivery
PaperId: :  14021
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 7 Issue 2 2021
DUI:    16.0415/IJARIIE-14021
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Patel Alexkumar MansukhlalB.N.B Swaminarayan Pharmacy Colleg
Narkhede Kantilal BB.N.B Swaminarayan Pharmacy Colleg
Prajapati Anuradha PB.N.B Swaminarayan Pharmacy Colleg
Narkhede Sachin BB.N.B Swaminarayan Pharmacy Colleg

Abstract

Pharmaceutical
secnidazole, antibacterial, insitu gel, Carbopol 934, local action, Invitro-diffusion
The aim of the study was to formulate and develop the insitu gel of secnidazole for vaginal route. Secnidazole is a second generation antibacterial drug with fewer side effects than other antibacterial drug. Present formulation is prepared to provide local action. With the help of pH triggered system, the present formulation convert from solution to gel when change occur from normal pH (3.5-4.5) .The insitu gel is prepared by using Carbopol 934 as pH sensitive agent and HPMC K-100M as Mucoadhesive agent. The preliminary trials were performed by using polymer of various concentrations of guar gum, Xanthan gum and Carbopol 934.The preliminary batches were studied for gelation property and selection of polymer is done. The prepared formulations were then evaluated for visual appearance, pH measurement, rheological studies, clarity, gelling capacity and drug content.

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IJARIIE Patel Alexkumar Mansukhlal, Narkhede Kantilal B, Prajapati Anuradha P, and Narkhede Sachin B. "FORMULATION DEVELOPMENT AND EVALUATION OF pH BASED INSITU VAGINAL GEL OF SECNIDAZOLE for vaginal delivery" International Journal Of Advance Research And Innovative Ideas In Education Volume 7 Issue 2 2021 Page 1229-1239
MLA Patel Alexkumar Mansukhlal, Narkhede Kantilal B, Prajapati Anuradha P, and Narkhede Sachin B. "FORMULATION DEVELOPMENT AND EVALUATION OF pH BASED INSITU VAGINAL GEL OF SECNIDAZOLE for vaginal delivery." International Journal Of Advance Research And Innovative Ideas In Education 7.2(2021) : 1229-1239.
APA Patel Alexkumar Mansukhlal, Narkhede Kantilal B, Prajapati Anuradha P, & Narkhede Sachin B. (2021). FORMULATION DEVELOPMENT AND EVALUATION OF pH BASED INSITU VAGINAL GEL OF SECNIDAZOLE for vaginal delivery. International Journal Of Advance Research And Innovative Ideas In Education, 7(2), 1229-1239.
Chicago Patel Alexkumar Mansukhlal, Narkhede Kantilal B, Prajapati Anuradha P, and Narkhede Sachin B. "FORMULATION DEVELOPMENT AND EVALUATION OF pH BASED INSITU VAGINAL GEL OF SECNIDAZOLE for vaginal delivery." International Journal Of Advance Research And Innovative Ideas In Education 7, no. 2 (2021) : 1229-1239.
Oxford Patel Alexkumar Mansukhlal, Narkhede Kantilal B, Prajapati Anuradha P, and Narkhede Sachin B. 'FORMULATION DEVELOPMENT AND EVALUATION OF pH BASED INSITU VAGINAL GEL OF SECNIDAZOLE for vaginal delivery', International Journal Of Advance Research And Innovative Ideas In Education, vol. 7, no. 2, 2021, p. 1229-1239. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/FORMULATION_DEVELOPMENT_AND_EVALUATION_OF_pH_BASED_INSITU_VAGINAL_GEL_OF_SECNIDAZOLE_for_vaginal_delivery_ijariie14021.pdf (Accessed : ).
Harvard Patel Alexkumar Mansukhlal, Narkhede Kantilal B, Prajapati Anuradha P, and Narkhede Sachin B. (2021) 'FORMULATION DEVELOPMENT AND EVALUATION OF pH BASED INSITU VAGINAL GEL OF SECNIDAZOLE for vaginal delivery', International Journal Of Advance Research And Innovative Ideas In Education, 7(2), pp. 1229-1239IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/FORMULATION_DEVELOPMENT_AND_EVALUATION_OF_pH_BASED_INSITU_VAGINAL_GEL_OF_SECNIDAZOLE_for_vaginal_delivery_ijariie14021.pdf (Accessed : )
IEEE Patel Alexkumar Mansukhlal, Narkhede Kantilal B, Prajapati Anuradha P, and Narkhede Sachin B, "FORMULATION DEVELOPMENT AND EVALUATION OF pH BASED INSITU VAGINAL GEL OF SECNIDAZOLE for vaginal delivery," International Journal Of Advance Research And Innovative Ideas In Education, vol. 7, no. 2, pp. 1229-1239, Mar-App 2021. [Online]. Available: https://ijariie.com/AdminUploadPdf/FORMULATION_DEVELOPMENT_AND_EVALUATION_OF_pH_BASED_INSITU_VAGINAL_GEL_OF_SECNIDAZOLE_for_vaginal_delivery_ijariie14021.pdf [Accessed : ].
Turabian Patel Alexkumar Mansukhlal, Narkhede Kantilal B, Prajapati Anuradha P, and Narkhede Sachin B. "FORMULATION DEVELOPMENT AND EVALUATION OF pH BASED INSITU VAGINAL GEL OF SECNIDAZOLE for vaginal delivery." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 7 number 2 ().
Vancouver Patel Alexkumar Mansukhlal, Narkhede Kantilal B, Prajapati Anuradha P, and Narkhede Sachin B. FORMULATION DEVELOPMENT AND EVALUATION OF pH BASED INSITU VAGINAL GEL OF SECNIDAZOLE for vaginal delivery. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2021 [Cited : ]; 7(2) : 1229-1239. Available from: https://ijariie.com/AdminUploadPdf/FORMULATION_DEVELOPMENT_AND_EVALUATION_OF_pH_BASED_INSITU_VAGINAL_GEL_OF_SECNIDAZOLE_for_vaginal_delivery_ijariie14021.pdf
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