Call for Papers:Vol.10 Issue.6

Submission
Last date		 30-Dec-2024
Acceptance Status In One Day
Paper Publish In Two Days
Submit ManuScript

News & Updates

Submit Article

Dear Authors, Article publish in our journal for Volume-10,Issue-6. For article submission on below link: Submit Manuscript


Join As Board

Dear Reviewer, You can join our Reviewer team without given any charges in our journal. Submit Details on below link: Join As Board


Paper Publication Charges

IJARIIE APP
Download Android App

For Authors

Archives

IJARIIE Board

Downloads

Android App

Download IJARIIE APP

Authors

Title: :  DEVELOPMENT AND EVALAUATION OF FROVATRIPTAN BIOADHESIVE FILMS
PaperId: :  14312
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 7 Issue 3 2021
DUI:    16.0415/IJARIIE-14312
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Muthyala AnithaSt.Peter’s Institute of Pharmaceutical Science,Hanmakonda,Warangal,Telangana,India.
Banoth SravaniSt.Peter’s Institute of Pharmaceutical Science,Hanmakonda,Warangal,Telangana,India.
Gundu Swathi,St.Peter’s Institute of Pharmaceutical Science,Hanmakonda,Warangal,Telangana,India.
Peddineni DivyasreeSt.Peter’s Institute of Pharmaceutical Science,Hanmakonda,Warangal,Telangana,India.

Abstract

Pharmacy
Mucoadhesive films, Frovatriptan, Migraine, HPMC K15, Beta-cyclodextrin, Eudragit L 100, Chitosan
Formulation development for new drugs, an extension of formulations, finding an alternative to conventional dosage forms for better therapeutic response are some of the research impetus in Pharmaceutical F and D. The new -untried routes of administration are also an avenue that can be explored. Under this research frovatriptan, an antimigraine, BCS class II drug is formulated into mucoadhesive films. Frovatriptan shows 40 to 50% oral bioavailability owing to its low solubility and degradation in GIT. Mucoadhesive films can be an effective formulation for this drug owing to its good permeability. Direct absorption in blood and preventing GIT degradation by mucoadhesion on buccal mucosa can be two rationales stated for the improvement of bioavailability of frovatriptan via mucoadhesive films. Migraine strikes as abrupt and disturbing health situation and needs immediate treatment. Thus, the mucoadhesive film can be more promising than oral tablets for frovatriptan in the treatment of migraine. Blank mucoadhesive films were prepared using various combinations of. HPMC K15, Eudragit L 100, whereas concentrations of chitosan, PVA, beta-cyclodextrin, Na CMC were selected from the literature survey. Later 2.5 mg per 2 × 2 cm2 drug-loaded formulations were developed and optimized. Factorial design of 32 models suggested F1 be optimized batch. Evaluation of films for mechanical and drug release studies along with stability study suggested that mucoadhesive films can be a successful formulation for frovatriptan for the management of migraine. Such formulation can have commercial applications, too, as no such formulation is yet available.

Citations

Copy and paste a formatted citation or use one of the links to import into a bibliography manager and reference.

IJARIIE Muthyala Anitha, Banoth Sravani, Gundu Swathi,, and Peddineni Divyasree. "DEVELOPMENT AND EVALAUATION OF FROVATRIPTAN BIOADHESIVE FILMS" International Journal Of Advance Research And Innovative Ideas In Education Volume 7 Issue 3 2021 Page 888-898
MLA Muthyala Anitha, Banoth Sravani, Gundu Swathi,, and Peddineni Divyasree. "DEVELOPMENT AND EVALAUATION OF FROVATRIPTAN BIOADHESIVE FILMS." International Journal Of Advance Research And Innovative Ideas In Education 7.3(2021) : 888-898.
APA Muthyala Anitha, Banoth Sravani, Gundu Swathi,, & Peddineni Divyasree. (2021). DEVELOPMENT AND EVALAUATION OF FROVATRIPTAN BIOADHESIVE FILMS. International Journal Of Advance Research And Innovative Ideas In Education, 7(3), 888-898.
Chicago Muthyala Anitha, Banoth Sravani, Gundu Swathi,, and Peddineni Divyasree. "DEVELOPMENT AND EVALAUATION OF FROVATRIPTAN BIOADHESIVE FILMS." International Journal Of Advance Research And Innovative Ideas In Education 7, no. 3 (2021) : 888-898.
Oxford Muthyala Anitha, Banoth Sravani, Gundu Swathi,, and Peddineni Divyasree. 'DEVELOPMENT AND EVALAUATION OF FROVATRIPTAN BIOADHESIVE FILMS', International Journal Of Advance Research And Innovative Ideas In Education, vol. 7, no. 3, 2021, p. 888-898. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_EVALAUATION_OF_FROVATRIPTAN_BIOADHESIVE_FILMS_ijariie14312.pdf (Accessed : ).
Harvard Muthyala Anitha, Banoth Sravani, Gundu Swathi,, and Peddineni Divyasree. (2021) 'DEVELOPMENT AND EVALAUATION OF FROVATRIPTAN BIOADHESIVE FILMS', International Journal Of Advance Research And Innovative Ideas In Education, 7(3), pp. 888-898IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_EVALAUATION_OF_FROVATRIPTAN_BIOADHESIVE_FILMS_ijariie14312.pdf (Accessed : )
IEEE Muthyala Anitha, Banoth Sravani, Gundu Swathi,, and Peddineni Divyasree, "DEVELOPMENT AND EVALAUATION OF FROVATRIPTAN BIOADHESIVE FILMS," International Journal Of Advance Research And Innovative Ideas In Education, vol. 7, no. 3, pp. 888-898, May-Jun 2021. [Online]. Available: https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_EVALAUATION_OF_FROVATRIPTAN_BIOADHESIVE_FILMS_ijariie14312.pdf [Accessed : ].
Turabian Muthyala Anitha, Banoth Sravani, Gundu Swathi,, and Peddineni Divyasree. "DEVELOPMENT AND EVALAUATION OF FROVATRIPTAN BIOADHESIVE FILMS." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 7 number 3 ().
Vancouver Muthyala Anitha, Banoth Sravani, Gundu Swathi,, and Peddineni Divyasree. DEVELOPMENT AND EVALAUATION OF FROVATRIPTAN BIOADHESIVE FILMS. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2021 [Cited : ]; 7(3) : 888-898. Available from: https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_EVALAUATION_OF_FROVATRIPTAN_BIOADHESIVE_FILMS_ijariie14312.pdf
BibTex EndNote RefMan RefWorks

Number Of Downloads



Save in Google Drive

Similar-Paper

TitleArea of ResearchAuther NameAction
A comprehensive review on Flaxseeds: Nutritional profile, food uses and health benefitsPharmacyMs. Samruddhi Rajpure Download
A comprehensive review on Enicostemma Littorale Blume as an Ayurvedic HerbPharmacyMr. Prasad Bhopale Download
REVIEW ON SHANKHPUSHPI IN NEUROLOGICAL DISORDERSpharmacognosyAbhilash Kutlehria Download
"MARFAN SYNDROME: A COMPREHENSIVE GUIDE TO PATHOGENESIS, DIAGNOSIS, TREATMENT AND MEDICAL MANAGEMENT"Pharmacy Vishvajit Bharat Waghmare Download
To Study On Etiology, Symptoms, Diagnosis ,Treatment and Therapeutic Outcome Of ‘DENGUE FEVER’PHARMACYMELAM.YESURATNAM Download
A review on Nutritional requirements during pregnancyPharmacy Rode Nikita Shivaji Download
DEVELOPMENT AND CHARACTERIZATION OF ORAL MICRO-PARTICULATE DRUG DELIVERY SYSTEMPharmacyAbhilashkutlehria Download
Composition and Analyzation of Transdermal Diclofenac Sodium PatchesPharmacyAbhilash Kutlehria Download
A REVIEW ON HERBAL MEDICINE PLANTS ARE USED FOR THE TREATMENT OF EYE DISORDERS.PHARMACYManoj AN Download
Validation of Sitagliptin Phosphate & Simvastatin by RP-HPLCPharmaceutical Science Sahil Ravindra Chavhan Download
Method Development and Validation of Kaempferol by using High Performance Liquid ChromatographyPharmacyReena Nanasaheb Autade Download
Cheilocostus Speciosus Traditional Uses And TaxonomyPharmacyRajat Kumar Download
Evaluation of Medicinal Plants for Their Therapeutic Potential in Wound ManagementM. Pharmacy (Pharmacology)Aniket Dhadwal Download
A PROSPECTIVE REVIEW ON TRANSETHASOMAL GEL AS CARRIER FOR ENHANCING TRANSDERMAL DELIVERYPharmaceutical FormulationMohammad amin Yatoo Download
FORMULATION AND EVALUATION OF POLY HERBAL FACE MASKpharmacyVANASHRI TURKE Download
12