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Title: :  Prevalence of Anti Thyroid Peroxidase Antibody in Hypothyroid Patient.
PaperId: :  14663
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 7 Issue 3 2021
DUI:    16.0415/IJARIIE-14663
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Dr. Khagendra Jung ShahBheri Hospital, Nepalgunj, Nepal
Dr. Rajesh Kumar MandalBheri Hospital, Nepalgunj, Nepal

Abstract

Medicine
Autoimmune, Anti Thyroid peroxidase, Hashimoto’s thyroiditis, Hypothyroidism.
Background: Anti- Thyroid perioxidase (TPO) autoantibodies are very important in diagnosis of autoimmune thyroid diseases. It can be used as predictor of its clinical course from subclinical to overt hypothyroidism. Thus this study was conducted to describe the clinical manifestations of chronic Hashimoto’s thyroiditis and prevalence of Anti TPO Antibodies in a population suffering from primary hypothyroidism. Methodology: The study was a hospital based, cross sectional study involving 50 cases, who presented with primary hypothyroidism to endocrine and medicine outpatient department between August 2015 to August 2016. The patients’ history, physical examination, routine blood investigations and anti TPO Ab testing was done. Statistical analysis was done using SPSS 16 software. Results: Among 50 cases of primary hypothyroidism, 14 (28%) had TPO antibody positive. Female patients were more likely to be TPO antibody positive (37% vs 6.67% : F vs M). TPO positive patients had high mean TSH value (26.61 vs 13.39) as compared to that of TPO negative patients which was statistically significant (p<0.05). The most frequent symptoms of TPO positive patients were lethargy, tingling sensation and weight gain and the most frequent signs were facial puffiness neck swelling and non-pitting pedal edema. Conclusions: Hashimoto`s thyroiditis was the common cause of primary hypothyroidism in the study. It could not be differentiated on the basis of clinical presentation. Anti TPO Antibodies testing should be done in subclinical hypothyroidism.

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IJARIIE Dr. Khagendra Jung Shah, and Dr. Rajesh Kumar Mandal. "Prevalence of Anti Thyroid Peroxidase Antibody in Hypothyroid Patient." International Journal Of Advance Research And Innovative Ideas In Education Volume 7 Issue 3 2021 Page 2771-2777
MLA Dr. Khagendra Jung Shah, and Dr. Rajesh Kumar Mandal. "Prevalence of Anti Thyroid Peroxidase Antibody in Hypothyroid Patient.." International Journal Of Advance Research And Innovative Ideas In Education 7.3(2021) : 2771-2777.
APA Dr. Khagendra Jung Shah, & Dr. Rajesh Kumar Mandal. (2021). Prevalence of Anti Thyroid Peroxidase Antibody in Hypothyroid Patient.. International Journal Of Advance Research And Innovative Ideas In Education, 7(3), 2771-2777.
Chicago Dr. Khagendra Jung Shah, and Dr. Rajesh Kumar Mandal. "Prevalence of Anti Thyroid Peroxidase Antibody in Hypothyroid Patient.." International Journal Of Advance Research And Innovative Ideas In Education 7, no. 3 (2021) : 2771-2777.
Oxford Dr. Khagendra Jung Shah, and Dr. Rajesh Kumar Mandal. 'Prevalence of Anti Thyroid Peroxidase Antibody in Hypothyroid Patient.', International Journal Of Advance Research And Innovative Ideas In Education, vol. 7, no. 3, 2021, p. 2771-2777. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Prevalence_of_Anti_Thyroid_Peroxidase_Antibody_in_Hypothyroid_Patient__ijariie14663.pdf (Accessed : ).
Harvard Dr. Khagendra Jung Shah, and Dr. Rajesh Kumar Mandal. (2021) 'Prevalence of Anti Thyroid Peroxidase Antibody in Hypothyroid Patient.', International Journal Of Advance Research And Innovative Ideas In Education, 7(3), pp. 2771-2777IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Prevalence_of_Anti_Thyroid_Peroxidase_Antibody_in_Hypothyroid_Patient__ijariie14663.pdf (Accessed : )
IEEE Dr. Khagendra Jung Shah, and Dr. Rajesh Kumar Mandal, "Prevalence of Anti Thyroid Peroxidase Antibody in Hypothyroid Patient.," International Journal Of Advance Research And Innovative Ideas In Education, vol. 7, no. 3, pp. 2771-2777, May-Jun 2021. [Online]. Available: https://ijariie.com/AdminUploadPdf/Prevalence_of_Anti_Thyroid_Peroxidase_Antibody_in_Hypothyroid_Patient__ijariie14663.pdf [Accessed : ].
Turabian Dr. Khagendra Jung Shah, and Dr. Rajesh Kumar Mandal. "Prevalence of Anti Thyroid Peroxidase Antibody in Hypothyroid Patient.." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 7 number 3 ().
Vancouver Dr. Khagendra Jung Shah, and Dr. Rajesh Kumar Mandal. Prevalence of Anti Thyroid Peroxidase Antibody in Hypothyroid Patient.. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2021 [Cited : ]; 7(3) : 2771-2777. Available from: https://ijariie.com/AdminUploadPdf/Prevalence_of_Anti_Thyroid_Peroxidase_Antibody_in_Hypothyroid_Patient__ijariie14663.pdf
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