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Title: :  Peptide-based synthetic vaccines
PaperId: :  15185
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 7 Issue 4 2021
DUI:    16.0415/IJARIIE-15185
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
vaibhavikarnatak university

Abstract

organic chemistry
peptide, vaccine
Classically all vaccines were produced using live or attenuated microorganisms or parts of them. However, the use of whole organisms, their components or the biological process for vaccine production has several weaknesses. The presence of immunologically redundant biological components or biological impurities in such vaccines might cause major problems. All the disadvantageous of traditional vaccines might be overcome via the development of fully synthetic peptide-based vaccines. However, once minimal antigenic epitopes only are applied for immunisation, the immune responses are poor. The use of an adjuvant can overcome this obstacle; however, it may raise new glitches. Here we briefly summarise the current stand on peptide-based vaccines, discuss epitope and adjuvant design, and multi- epitope and nanoparticle-based vaccine approaches. This mini review discusses also the disadvantages and benefits associated with peptide-based vaccines. It proposes possible methods to overcome the weaknesses of the synthetic vaccine strategy and suggests future directions for its development.

Citations

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IJARIIE vaibhavi. "Peptide-based synthetic vaccines" International Journal Of Advance Research And Innovative Ideas In Education Volume 7 Issue 4 2021 Page 2038-2049
MLA vaibhavi. "Peptide-based synthetic vaccines." International Journal Of Advance Research And Innovative Ideas In Education 7.4(2021) : 2038-2049.
APA vaibhavi. (2021). Peptide-based synthetic vaccines. International Journal Of Advance Research And Innovative Ideas In Education, 7(4), 2038-2049.
Chicago vaibhavi. "Peptide-based synthetic vaccines." International Journal Of Advance Research And Innovative Ideas In Education 7, no. 4 (2021) : 2038-2049.
Oxford vaibhavi. 'Peptide-based synthetic vaccines', International Journal Of Advance Research And Innovative Ideas In Education, vol. 7, no. 4, 2021, p. 2038-2049. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Peptide_based_synthetic_vaccines_ijariie15185.pdf (Accessed : ).
Harvard vaibhavi. (2021) 'Peptide-based synthetic vaccines', International Journal Of Advance Research And Innovative Ideas In Education, 7(4), pp. 2038-2049IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Peptide_based_synthetic_vaccines_ijariie15185.pdf (Accessed : )
IEEE vaibhavi, "Peptide-based synthetic vaccines," International Journal Of Advance Research And Innovative Ideas In Education, vol. 7, no. 4, pp. 2038-2049, Jul-Aug 2021. [Online]. Available: https://ijariie.com/AdminUploadPdf/Peptide_based_synthetic_vaccines_ijariie15185.pdf [Accessed : ].
Turabian vaibhavi. "Peptide-based synthetic vaccines." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 7 number 4 ().
Vancouver vaibhavi. Peptide-based synthetic vaccines. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2021 [Cited : ]; 7(4) : 2038-2049. Available from: https://ijariie.com/AdminUploadPdf/Peptide_based_synthetic_vaccines_ijariie15185.pdf
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