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Title: :  Design and Characterization of Polymeric Microspheres of Azilsartan
PaperId: :  16462
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 8 Issue 2 2022
DUI:    16.0415/IJARIIE-16462
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
K.Vandana1*K.v.k college of pharmacy
,Dr.S.Venakata Saibaba1 K.v.k college of pharmacy
Dr.B.Prabhakar Reddy2, vignan institute of pharmaceutical sciences
Eslavath Ravinder Naik1,K.v.k college of pharmacy

Abstract

pharmacy
Microspheres, Azilsartan , Solvent Evaporation method, Bioavailability enhancement.
Azilsartan (AZ) is a BCS-class II drug that is insoluble in water and has a low bioavailability (13%). The aim of the present work was to prepare the microspheres of Azilsartan improving solubility and hence bioavailability. The microspheres of Azilsartan was prepared by solvent evaporation technique with Eudragit RL 100 by using various ratios (1:1, 1:3 and 1:5).Microspheres was evaluated by Fourier Transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM),Differential scanning electron microscopy, Saturation solubility and in-vitro studies. The solid state characterization revealed that no drug polymer interaction and the formulations F2 shows (1:3) better in vitro drug release from other formulation. Among these three formulations F2 shows better sustained release than F1 and F3. As a result, drug loaded microsphere appear to be a promising approach for increasing the solubility and bioavailability of Azilsartan .

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IJARIIE K.Vandana1*, ,Dr.S.Venakata Saibaba1 , Dr.B.Prabhakar Reddy2, , and Eslavath Ravinder Naik1,. "Design and Characterization of Polymeric Microspheres of Azilsartan" International Journal Of Advance Research And Innovative Ideas In Education Volume 8 Issue 2 2022 Page 1757-1766
MLA K.Vandana1*, ,Dr.S.Venakata Saibaba1 , Dr.B.Prabhakar Reddy2, , and Eslavath Ravinder Naik1,. "Design and Characterization of Polymeric Microspheres of Azilsartan." International Journal Of Advance Research And Innovative Ideas In Education 8.2(2022) : 1757-1766.
APA K.Vandana1*, ,Dr.S.Venakata Saibaba1 , Dr.B.Prabhakar Reddy2, , & Eslavath Ravinder Naik1,. (2022). Design and Characterization of Polymeric Microspheres of Azilsartan. International Journal Of Advance Research And Innovative Ideas In Education, 8(2), 1757-1766.
Chicago K.Vandana1*, ,Dr.S.Venakata Saibaba1 , Dr.B.Prabhakar Reddy2, , and Eslavath Ravinder Naik1,. "Design and Characterization of Polymeric Microspheres of Azilsartan." International Journal Of Advance Research And Innovative Ideas In Education 8, no. 2 (2022) : 1757-1766.
Oxford K.Vandana1*, ,Dr.S.Venakata Saibaba1 , Dr.B.Prabhakar Reddy2, , and Eslavath Ravinder Naik1,. 'Design and Characterization of Polymeric Microspheres of Azilsartan', International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 2, 2022, p. 1757-1766. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Design_and_Characterization_of_Polymeric_Microspheres_of_Azilsartan_ijariie16462.pdf (Accessed : ).
Harvard K.Vandana1*, ,Dr.S.Venakata Saibaba1 , Dr.B.Prabhakar Reddy2, , and Eslavath Ravinder Naik1,. (2022) 'Design and Characterization of Polymeric Microspheres of Azilsartan', International Journal Of Advance Research And Innovative Ideas In Education, 8(2), pp. 1757-1766IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Design_and_Characterization_of_Polymeric_Microspheres_of_Azilsartan_ijariie16462.pdf (Accessed : )
IEEE K.Vandana1*, ,Dr.S.Venakata Saibaba1 , Dr.B.Prabhakar Reddy2, , and Eslavath Ravinder Naik1,, "Design and Characterization of Polymeric Microspheres of Azilsartan," International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 2, pp. 1757-1766, Mar-App 2022. [Online]. Available: https://ijariie.com/AdminUploadPdf/Design_and_Characterization_of_Polymeric_Microspheres_of_Azilsartan_ijariie16462.pdf [Accessed : ].
Turabian K.Vandana1*, ,Dr.S.Venakata Saibaba1 , Dr.B.Prabhakar Reddy2, , and Eslavath Ravinder Naik1,. "Design and Characterization of Polymeric Microspheres of Azilsartan." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 8 number 2 ().
Vancouver K.Vandana1*, ,Dr.S.Venakata Saibaba1 , Dr.B.Prabhakar Reddy2, , and Eslavath Ravinder Naik1,. Design and Characterization of Polymeric Microspheres of Azilsartan. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2022 [Cited : ]; 8(2) : 1757-1766. Available from: https://ijariie.com/AdminUploadPdf/Design_and_Characterization_of_Polymeric_Microspheres_of_Azilsartan_ijariie16462.pdf
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