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Title: :  STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY
PaperId: :  17579
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 8 Issue 3 2022
DUI:    16.0415/IJARIIE-17579
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Susan PradhanPokhara Academy of Health Sciences, Pokhara, Nepal
Sadikshya ShresthaTribhuvan University Teaching Hospital, Kathmandu, Nepal
Sandip ShresthaPokhara Academy of Health Sciences, Pokhara, Nepal
Ajay K.CPokhara Academy of Health Sciences, Pokhara, Nepal
Sandesh DorangaPokhara Academy of Health Sciences, Pokhara, Nepal
Sangam RayamajhiTribhuvan University Teaching Hospital, Kathmandu, Nepal
Jayan Man ShresthaTribhuvan University Teaching Hospital, Kathmandu, Nepal

Abstract

Biological and Medical Sciences
Surgical site infections (SSIs), Skin antisepsis, Chlorhexidine alcohol (CHA), Povidone iodine (PI), Uncomplicated Emergency Open Appendectomy.
Introduction: Surgical site infections (SSIs) cause severe morbidity and mortality along with enormous health costs. Skin antisepsis with chlorhexidine alcohol solutions has demonstrated superiority to povidone-iodine for the prevention of SSIs. Our objective was to determine if chlorhexidine-alcohol reduces the rate of SSIs in uncomplicated emergency open appendectomy compared with povidone-iodine and also analyze risk factors associated with SSIs. Materials and Methods: This study was carried out at Tribhuvan University Teaching Hospital, Kathmandu. A total of 88 patients with acute uncomplicated appendicitis who underwent uncomplicated emergency open appendectomy were included. The protocols for antisepsis were use of 10% povidone-iodine (n = 44) and 2% chlorhexidine in 80% isopropyl alcohol (n= 44) over the surgical site. The rates of SSIs as defined by the Centers for Disease Control and Prevention (CDC) and risk factors for the occurrence of SSIs were determined. Result: The two groups of patients were similar in regard to baseline characteristics and medical history. Thirteen patients (14.77%) developed superficial SSI. There was no significant difference between the two study groups in incidence of SSI (relative risk,0.57; 95% CI, 0.17 to 1.92). Antisepsis with chlorhexidine-alcohol was not associated with a reduction in the overall rate of SSI (11.4 % vs 18.2%, p= 0.37). Smoking was found to be associated with SSI in povidone-iodine group (p=0.042). Conclusion: This study demonstrates that chlorhexidine-alcohol showed similar antiseptic role as povidone-iodine in patients undergoing uncomplicated emergency open appendectomy in preventing SSI. This is of vital clinical importance for developing country like Nepal where povidone-iodine is the antisepsis of choice in daily surgical practice.

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IJARIIE Susan Pradhan, Sadikshya Shrestha, Sandip Shrestha, Ajay K.C, Sandesh Doranga, Sangam Rayamajhi, and Jayan Man Shrestha. "STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY" International Journal Of Advance Research And Innovative Ideas In Education Volume 8 Issue 3 2022 Page 5406-5415
MLA Susan Pradhan, Sadikshya Shrestha, Sandip Shrestha, Ajay K.C, Sandesh Doranga, Sangam Rayamajhi, and Jayan Man Shrestha. "STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY." International Journal Of Advance Research And Innovative Ideas In Education 8.3(2022) : 5406-5415.
APA Susan Pradhan, Sadikshya Shrestha, Sandip Shrestha, Ajay K.C, Sandesh Doranga, Sangam Rayamajhi, & Jayan Man Shrestha. (2022). STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY. International Journal Of Advance Research And Innovative Ideas In Education, 8(3), 5406-5415.
Chicago Susan Pradhan, Sadikshya Shrestha, Sandip Shrestha, Ajay K.C, Sandesh Doranga, Sangam Rayamajhi, and Jayan Man Shrestha. "STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY." International Journal Of Advance Research And Innovative Ideas In Education 8, no. 3 (2022) : 5406-5415.
Oxford Susan Pradhan, Sadikshya Shrestha, Sandip Shrestha, Ajay K.C, Sandesh Doranga, Sangam Rayamajhi, and Jayan Man Shrestha. 'STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY', International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 3, 2022, p. 5406-5415. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/STUDY_OF_CHLORHEXIDINE_ALCOHOL_AND_POVIDONE_IODINE_FOR_SURGICAL_SITE_ANTISEPSIS_IN_UNCOMPLICATED_EMERGENCY_OPEN_APPENDECTOMY_ijariie17579.pdf (Accessed : 24 June 2025).
Harvard Susan Pradhan, Sadikshya Shrestha, Sandip Shrestha, Ajay K.C, Sandesh Doranga, Sangam Rayamajhi, and Jayan Man Shrestha. (2022) 'STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY', International Journal Of Advance Research And Innovative Ideas In Education, 8(3), pp. 5406-5415IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/STUDY_OF_CHLORHEXIDINE_ALCOHOL_AND_POVIDONE_IODINE_FOR_SURGICAL_SITE_ANTISEPSIS_IN_UNCOMPLICATED_EMERGENCY_OPEN_APPENDECTOMY_ijariie17579.pdf (Accessed : 24 June 2025)
IEEE Susan Pradhan, Sadikshya Shrestha, Sandip Shrestha, Ajay K.C, Sandesh Doranga, Sangam Rayamajhi, and Jayan Man Shrestha, "STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY," International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 3, pp. 5406-5415, May-Jun 2022. [Online]. Available: https://ijariie.com/AdminUploadPdf/STUDY_OF_CHLORHEXIDINE_ALCOHOL_AND_POVIDONE_IODINE_FOR_SURGICAL_SITE_ANTISEPSIS_IN_UNCOMPLICATED_EMERGENCY_OPEN_APPENDECTOMY_ijariie17579.pdf [Accessed : 24 June 2025].
Turabian Susan Pradhan, Sadikshya Shrestha, Sandip Shrestha, Ajay K.C, Sandesh Doranga, Sangam Rayamajhi, and Jayan Man Shrestha. "STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 8 number 3 (24 June 2025).
Vancouver Susan Pradhan, Sadikshya Shrestha, Sandip Shrestha, Ajay K.C, Sandesh Doranga, Sangam Rayamajhi, and Jayan Man Shrestha. STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2022 [Cited : 24 June 2025]; 8(3) : 5406-5415. Available from: https://ijariie.com/AdminUploadPdf/STUDY_OF_CHLORHEXIDINE_ALCOHOL_AND_POVIDONE_IODINE_FOR_SURGICAL_SITE_ANTISEPSIS_IN_UNCOMPLICATED_EMERGENCY_OPEN_APPENDECTOMY_ijariie17579.pdf
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