Call for Papers:Vol.10 Issue.6

Submission
Last date		 30-Dec-2024
Acceptance Status In One Day
Paper Publish In Two Days
Submit ManuScript

News & Updates

Submit Article

Dear Authors, Article publish in our journal for Volume-10,Issue-6. For article submission on below link: Submit Manuscript


Join As Board

Dear Reviewer, You can join our Reviewer team without given any charges in our journal. Submit Details on below link: Join As Board


Paper Publication Charges

IJARIIE APP
Download Android App

For Authors

Archives

IJARIIE Board

Downloads

Android App

Download IJARIIE APP

Authors

Title: :  DEVELOPMENT AND VALIDATION OF RP- HPLC METHOD FOR THE DETERMINATION OF RAMELTEON IN BULK AND PHARMACEUTICAL DOSAGE FORM
PaperId: :  17656
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 8 Issue 4 2022
DUI:    16.0415/IJARIIE-17656
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
MAAZ AAQUIL ALI ALLANA COLLEGE OF PHARMACY
SIDDIK M PATELALI ALLANA COLLEGE OF PHARMACY
KHAN JAVEDALI ALLANA COLLEGE OF PHARMACY
ABDUL BARIALI ALLANA COLLEGE OF PHARMACY
ANSARI MOHD HAMMADALI ALLANA COLLEGE OF PHARMACY
MOHD SHOEB NAWAZALI ALLANA COLLEGE OF PHARMACY
SHAIKH MUJEEB ALI ALLANA COLLEGE OF PHARMACY
TAMBOLI SAIFALIALI ALLANA COLLEGE OF PHARMACY

Abstract

PHARMACY
Keyword: Ramelteon, RP-HPLC Method Development, Anti-Anxiety, Validation.
Abstract: A simple, accurate and precise reverse phase HPLC method validated for the determination of Ramelteon Tablet dosage form. Chromatography was carried on C18 column using a mixture of Methanol: water (0.1 % OPA), pH 2.7 (in the ratio 60:40 v/v) as the mobile phase at a flow rate of 0.7 ml /min with detection at 282 nm by ultraviolet detector i.e. incorporated in HPLC. The retention time of the drug was found to be 5.860 min. The method validation proofs were carried out as per the ICH guidelines. The developed method was validated for linearity over a range of 10μg/ml to 60μg/ml, with a correlation coefficient of 0.999, which shows the method is quite linear. Further precision, ruggedness, accuracy was validated. The %RSD for system precision was observed to be Less Than 2, whereas the method precision was observed to be 0.456. And for ruggedness the observations were found to be 0.5 and 0.4 respectively. The average recovery of 100.0% indicates the capability of the method, and finally no significant differences in % RSD values with respective Retention time prove the robustness of the method. As per ICH guidelines, method validation results are in good agreement. The proposed approach is effective and can be applied for the tablet dosage form estimation of Ramelteon in tablet dosage form.

Citations

Copy and paste a formatted citation or use one of the links to import into a bibliography manager and reference.

IJARIIE MAAZ AAQUIL , SIDDIK M PATEL, KHAN JAVED, ABDUL BARI, ANSARI MOHD HAMMAD, MOHD SHOEB NAWAZ, SHAIKH MUJEEB , and TAMBOLI SAIFALI. "DEVELOPMENT AND VALIDATION OF RP- HPLC METHOD FOR THE DETERMINATION OF RAMELTEON IN BULK AND PHARMACEUTICAL DOSAGE FORM" International Journal Of Advance Research And Innovative Ideas In Education Volume 8 Issue 4 2022 Page 80-92
MLA MAAZ AAQUIL , SIDDIK M PATEL, KHAN JAVED, ABDUL BARI, ANSARI MOHD HAMMAD, MOHD SHOEB NAWAZ, SHAIKH MUJEEB , and TAMBOLI SAIFALI. "DEVELOPMENT AND VALIDATION OF RP- HPLC METHOD FOR THE DETERMINATION OF RAMELTEON IN BULK AND PHARMACEUTICAL DOSAGE FORM." International Journal Of Advance Research And Innovative Ideas In Education 8.4(2022) : 80-92.
APA MAAZ AAQUIL , SIDDIK M PATEL, KHAN JAVED, ABDUL BARI, ANSARI MOHD HAMMAD, MOHD SHOEB NAWAZ, SHAIKH MUJEEB , & TAMBOLI SAIFALI. (2022). DEVELOPMENT AND VALIDATION OF RP- HPLC METHOD FOR THE DETERMINATION OF RAMELTEON IN BULK AND PHARMACEUTICAL DOSAGE FORM. International Journal Of Advance Research And Innovative Ideas In Education, 8(4), 80-92.
Chicago MAAZ AAQUIL , SIDDIK M PATEL, KHAN JAVED, ABDUL BARI, ANSARI MOHD HAMMAD, MOHD SHOEB NAWAZ, SHAIKH MUJEEB , and TAMBOLI SAIFALI. "DEVELOPMENT AND VALIDATION OF RP- HPLC METHOD FOR THE DETERMINATION OF RAMELTEON IN BULK AND PHARMACEUTICAL DOSAGE FORM." International Journal Of Advance Research And Innovative Ideas In Education 8, no. 4 (2022) : 80-92.
Oxford MAAZ AAQUIL , SIDDIK M PATEL, KHAN JAVED, ABDUL BARI, ANSARI MOHD HAMMAD, MOHD SHOEB NAWAZ, SHAIKH MUJEEB , and TAMBOLI SAIFALI. 'DEVELOPMENT AND VALIDATION OF RP- HPLC METHOD FOR THE DETERMINATION OF RAMELTEON IN BULK AND PHARMACEUTICAL DOSAGE FORM', International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 4, 2022, p. 80-92. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_VALIDATION_OF_RP__HPLC_METHOD_FOR_THE_DETERMINATION_OF_RAMELTEON_IN_BULK_AND_PHARMACEUTICAL_DOSAGE_FORM_ijariie17656.pdf (Accessed : 03 August 2024).
Harvard MAAZ AAQUIL , SIDDIK M PATEL, KHAN JAVED, ABDUL BARI, ANSARI MOHD HAMMAD, MOHD SHOEB NAWAZ, SHAIKH MUJEEB , and TAMBOLI SAIFALI. (2022) 'DEVELOPMENT AND VALIDATION OF RP- HPLC METHOD FOR THE DETERMINATION OF RAMELTEON IN BULK AND PHARMACEUTICAL DOSAGE FORM', International Journal Of Advance Research And Innovative Ideas In Education, 8(4), pp. 80-92IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_VALIDATION_OF_RP__HPLC_METHOD_FOR_THE_DETERMINATION_OF_RAMELTEON_IN_BULK_AND_PHARMACEUTICAL_DOSAGE_FORM_ijariie17656.pdf (Accessed : 03 August 2024)
IEEE MAAZ AAQUIL , SIDDIK M PATEL, KHAN JAVED, ABDUL BARI, ANSARI MOHD HAMMAD, MOHD SHOEB NAWAZ, SHAIKH MUJEEB , and TAMBOLI SAIFALI, "DEVELOPMENT AND VALIDATION OF RP- HPLC METHOD FOR THE DETERMINATION OF RAMELTEON IN BULK AND PHARMACEUTICAL DOSAGE FORM," International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 4, pp. 80-92, Jul-Aug 2022. [Online]. Available: https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_VALIDATION_OF_RP__HPLC_METHOD_FOR_THE_DETERMINATION_OF_RAMELTEON_IN_BULK_AND_PHARMACEUTICAL_DOSAGE_FORM_ijariie17656.pdf [Accessed : 03 August 2024].
Turabian MAAZ AAQUIL , SIDDIK M PATEL, KHAN JAVED, ABDUL BARI, ANSARI MOHD HAMMAD, MOHD SHOEB NAWAZ, SHAIKH MUJEEB , and TAMBOLI SAIFALI. "DEVELOPMENT AND VALIDATION OF RP- HPLC METHOD FOR THE DETERMINATION OF RAMELTEON IN BULK AND PHARMACEUTICAL DOSAGE FORM." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 8 number 4 (03 August 2024).
Vancouver MAAZ AAQUIL , SIDDIK M PATEL, KHAN JAVED, ABDUL BARI, ANSARI MOHD HAMMAD, MOHD SHOEB NAWAZ, SHAIKH MUJEEB , and TAMBOLI SAIFALI. DEVELOPMENT AND VALIDATION OF RP- HPLC METHOD FOR THE DETERMINATION OF RAMELTEON IN BULK AND PHARMACEUTICAL DOSAGE FORM. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2022 [Cited : 03 August 2024]; 8(4) : 80-92. Available from: https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_VALIDATION_OF_RP__HPLC_METHOD_FOR_THE_DETERMINATION_OF_RAMELTEON_IN_BULK_AND_PHARMACEUTICAL_DOSAGE_FORM_ijariie17656.pdf
BibTex EndNote RefMan RefWorks

Number Of Downloads


Last download on 8/3/2024 9:10:42 AM

Save in Google Drive

Similar-Paper

TitleArea of ResearchAuther NameAction
A comprehensive review on Enicostemma Littorale Blume as an Ayurvedic HerbPharmacyMr. Prasad Bhopale Download
REVIEW ON SHANKHPUSHPI IN NEUROLOGICAL DISORDERSpharmacognosyAbhilash Kutlehria Download
"MARFAN SYNDROME: A COMPREHENSIVE GUIDE TO PATHOGENESIS, DIAGNOSIS, TREATMENT AND MEDICAL MANAGEMENT"Pharmacy Vishvajit Bharat Waghmare Download
To Study On Etiology, Symptoms, Diagnosis ,Treatment and Therapeutic Outcome Of ‘DENGUE FEVER’PHARMACYMELAM.YESURATNAM Download
A review on Nutritional requirements during pregnancyPharmacy Rode Nikita Shivaji Download
DEVELOPMENT AND CHARACTERIZATION OF ORAL MICRO-PARTICULATE DRUG DELIVERY SYSTEMPharmacyAbhilashkutlehria Download
Composition and Analyzation of Transdermal Diclofenac Sodium PatchesPharmacyAbhilash Kutlehria Download
A REVIEW ON HERBAL MEDICINE PLANTS ARE USED FOR THE TREATMENT OF EYE DISORDERS.PHARMACYManoj AN Download
Validation of Sitagliptin Phosphate & Simvastatin by RP-HPLCPharmaceutical Science Sahil Ravindra Chavhan Download
Method Development and Validation of Kaempferol by using High Performance Liquid ChromatographyPharmacyReena Nanasaheb Autade Download
Cheilocostus Speciosus Traditional Uses And TaxonomyPharmacyRajat Kumar Download
Evaluation of Medicinal Plants for Their Therapeutic Potential in Wound ManagementM. Pharmacy (Pharmacology)Aniket Dhadwal Download
A PROSPECTIVE REVIEW ON TRANSETHASOMAL GEL AS CARRIER FOR ENHANCING TRANSDERMAL DELIVERYPharmaceutical FormulationMohammad amin Yatoo Download
FORMULATION AND EVALUATION OF POLY HERBAL FACE MASKpharmacyVANASHRI TURKE Download
Formulation and Evaluation of Herbal Lip BalmB.pharmacy Shivani Maruti Lohar Download
12