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Title: :  FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.
PaperId: :  17683
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 8 Issue 4 2022
DUI:    16.0415/IJARIIE-17683
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Shaikh Mujeeb Musaali allana college of pharmacy
Tamboli Saifaliali allana college of pharmacy
Afsar Shaikhali allana college of pharmacy
Khan G J ali allana college of pharmacy
Amsari Hammadali allana college of pharmacy
Kasim Patelali allana college of pharmacy
Mohd. Shoeb Nawazali allana college of pharmacy
Patel Raihanali allana college of pharmacy

Abstract

pharmacy
Acetylcysteine, Sodium starch stearate glycolate, Polymethacrylate, Microcrystalline cellulose, Lactose and Mannitol
The aim of this work is to formulate and evaluate oral dispersing tablets of acetylcysteine to prevent disease associated with respiratory system mainly in bronchioles. Method which used for Preparation of tablet is direct compression method, with various super disintegrants like sodium starch glycolate, croscarmallose sodium, and Crospovidone at various concentrations (2%-20%). A total of eleven formulations were made using one type of super disintegrants for each formulation. Fourier Transmission InfraRed (FT-IR) and Differential Scanning Calorimetry studies (DSC) were performed to ensure the compatibility of drug with the super disintegrants. It was found to be satisfactory. The results of recompression studies reveals that the powder blends of all formulations acquire good flow properties. From the results of post compression studies for tablets of all formulations, it was concluded that the formulation containing 10% crospovidone as super disintegrants remerged as overall best formulation with lowest disintegration time and highest drug release rate.

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IJARIIE Shaikh Mujeeb Musa, Tamboli Saifali, Afsar Shaikh, Khan G J , Amsari Hammad, Kasim Patel, Mohd. Shoeb Nawaz, and Patel Raihan. "FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT." International Journal Of Advance Research And Innovative Ideas In Education Volume 8 Issue 4 2022 Page 294-300
MLA Shaikh Mujeeb Musa, Tamboli Saifali, Afsar Shaikh, Khan G J , Amsari Hammad, Kasim Patel, Mohd. Shoeb Nawaz, and Patel Raihan. "FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.." International Journal Of Advance Research And Innovative Ideas In Education 8.4(2022) : 294-300.
APA Shaikh Mujeeb Musa, Tamboli Saifali, Afsar Shaikh, Khan G J , Amsari Hammad, Kasim Patel, Mohd. Shoeb Nawaz, & Patel Raihan. (2022). FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.. International Journal Of Advance Research And Innovative Ideas In Education, 8(4), 294-300.
Chicago Shaikh Mujeeb Musa, Tamboli Saifali, Afsar Shaikh, Khan G J , Amsari Hammad, Kasim Patel, Mohd. Shoeb Nawaz, and Patel Raihan. "FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.." International Journal Of Advance Research And Innovative Ideas In Education 8, no. 4 (2022) : 294-300.
Oxford Shaikh Mujeeb Musa, Tamboli Saifali, Afsar Shaikh, Khan G J , Amsari Hammad, Kasim Patel, Mohd. Shoeb Nawaz, and Patel Raihan. 'FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.', International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 4, 2022, p. 294-300. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/FORMULATION_DESIGN_AND_EVALUATION_OF_ORODISPERSIBLE_TABLET_OF_ACETYLCYSTEINE_USING_SUPPERDISINTEGRANT__ijariie17683.pdf (Accessed : ).
Harvard Shaikh Mujeeb Musa, Tamboli Saifali, Afsar Shaikh, Khan G J , Amsari Hammad, Kasim Patel, Mohd. Shoeb Nawaz, and Patel Raihan. (2022) 'FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.', International Journal Of Advance Research And Innovative Ideas In Education, 8(4), pp. 294-300IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/FORMULATION_DESIGN_AND_EVALUATION_OF_ORODISPERSIBLE_TABLET_OF_ACETYLCYSTEINE_USING_SUPPERDISINTEGRANT__ijariie17683.pdf (Accessed : )
IEEE Shaikh Mujeeb Musa, Tamboli Saifali, Afsar Shaikh, Khan G J , Amsari Hammad, Kasim Patel, Mohd. Shoeb Nawaz, and Patel Raihan, "FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.," International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 4, pp. 294-300, Jul-Aug 2022. [Online]. Available: https://ijariie.com/AdminUploadPdf/FORMULATION_DESIGN_AND_EVALUATION_OF_ORODISPERSIBLE_TABLET_OF_ACETYLCYSTEINE_USING_SUPPERDISINTEGRANT__ijariie17683.pdf [Accessed : ].
Turabian Shaikh Mujeeb Musa, Tamboli Saifali, Afsar Shaikh, Khan G J , Amsari Hammad, Kasim Patel, Mohd. Shoeb Nawaz, and Patel Raihan. "FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 8 number 4 ().
Vancouver Shaikh Mujeeb Musa, Tamboli Saifali, Afsar Shaikh, Khan G J , Amsari Hammad, Kasim Patel, Mohd. Shoeb Nawaz, and Patel Raihan. FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2022 [Cited : ]; 8(4) : 294-300. Available from: https://ijariie.com/AdminUploadPdf/FORMULATION_DESIGN_AND_EVALUATION_OF_ORODISPERSIBLE_TABLET_OF_ACETYLCYSTEINE_USING_SUPPERDISINTEGRANT__ijariie17683.pdf
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