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Title: :  Formulation and Evaluation of Sustained Release Tablets of Losartan Potassium
PaperId: :  17697
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 8 Issue 4 2022
DUI:    16.0415/IJARIIE-17697
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
S.Rohini ReddySurabhi DayakarRao College of Pharmacy
CH.Shanthi PriyaSurabhi DayakarRao College of Pharmacy
Dr M Venkata RamanaSurabhi DayakarRao College of Pharmacy
M.PraveenSurabhi DayakarRao College of Pharmacy
K.SrikanthSurabhi DayakarRao College of Pharmacy
G.SrinivasSurabhi DayakarRao College of Pharmacy
CH.VaishnaviSurabhi DayakarRao College of Pharmacy
G.SuchithaSurabhi DayakarRao College of Pharmacy

Abstract

Pharmacy
Losartan potassium, Sustained release, ethyl cellulose, in-vitro drug release and anti- hypertensive drug
The present study was undertaken to develop sustained release (SR) tablets of Losartan potassium, an angiotensin-II antagonist for the treatment of hypertension. The tablets were prepared by wet granulation method, with ethyl cellulose. The amount of Losartan potassium remains fixed (100 mg) for all the six formulations whereas the amounts of ethyl cellulose were 50mg,60mg,70mg,80mg,90mg and 100mg for F-1, F-2, F-3, F-4, F-5 F-6 & F7 formulations respectively. The evaluation involves three stages: the micromeritic properties evaluation of granules, physical property studies of tablets, and in-vitro release kinetics studies. The USP apparatus type II was selected to perform the dissolution test, and the dissolution medium was 900 mL phosphate buffer pH 6.8. The test was carried out at 75 rpm, and the temperature was maintained at 37oC ± 0.5oC.

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IJARIIE S.Rohini Reddy, CH.Shanthi Priya, Dr M Venkata Ramana, M.Praveen, K.Srikanth, G.Srinivas, CH.Vaishnavi, and G.Suchitha. "Formulation and Evaluation of Sustained Release Tablets of Losartan Potassium" International Journal Of Advance Research And Innovative Ideas In Education Volume 8 Issue 4 2022 Page 378-382
MLA S.Rohini Reddy, CH.Shanthi Priya, Dr M Venkata Ramana, M.Praveen, K.Srikanth, G.Srinivas, CH.Vaishnavi, and G.Suchitha. "Formulation and Evaluation of Sustained Release Tablets of Losartan Potassium." International Journal Of Advance Research And Innovative Ideas In Education 8.4(2022) : 378-382.
APA S.Rohini Reddy, CH.Shanthi Priya, Dr M Venkata Ramana, M.Praveen, K.Srikanth, G.Srinivas, CH.Vaishnavi, & G.Suchitha. (2022). Formulation and Evaluation of Sustained Release Tablets of Losartan Potassium. International Journal Of Advance Research And Innovative Ideas In Education, 8(4), 378-382.
Chicago S.Rohini Reddy, CH.Shanthi Priya, Dr M Venkata Ramana, M.Praveen, K.Srikanth, G.Srinivas, CH.Vaishnavi, and G.Suchitha. "Formulation and Evaluation of Sustained Release Tablets of Losartan Potassium." International Journal Of Advance Research And Innovative Ideas In Education 8, no. 4 (2022) : 378-382.
Oxford S.Rohini Reddy, CH.Shanthi Priya, Dr M Venkata Ramana, M.Praveen, K.Srikanth, G.Srinivas, CH.Vaishnavi, and G.Suchitha. 'Formulation and Evaluation of Sustained Release Tablets of Losartan Potassium', International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 4, 2022, p. 378-382. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Formulation_and_Evaluation_of_Sustained_Release_Tablets_of_Losartan_Potassium_ijariie17697.pdf (Accessed : ).
Harvard S.Rohini Reddy, CH.Shanthi Priya, Dr M Venkata Ramana, M.Praveen, K.Srikanth, G.Srinivas, CH.Vaishnavi, and G.Suchitha. (2022) 'Formulation and Evaluation of Sustained Release Tablets of Losartan Potassium', International Journal Of Advance Research And Innovative Ideas In Education, 8(4), pp. 378-382IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Formulation_and_Evaluation_of_Sustained_Release_Tablets_of_Losartan_Potassium_ijariie17697.pdf (Accessed : )
IEEE S.Rohini Reddy, CH.Shanthi Priya, Dr M Venkata Ramana, M.Praveen, K.Srikanth, G.Srinivas, CH.Vaishnavi, and G.Suchitha, "Formulation and Evaluation of Sustained Release Tablets of Losartan Potassium," International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 4, pp. 378-382, Jul-Aug 2022. [Online]. Available: https://ijariie.com/AdminUploadPdf/Formulation_and_Evaluation_of_Sustained_Release_Tablets_of_Losartan_Potassium_ijariie17697.pdf [Accessed : ].
Turabian S.Rohini Reddy, CH.Shanthi Priya, Dr M Venkata Ramana, M.Praveen, K.Srikanth, G.Srinivas, CH.Vaishnavi, and G.Suchitha. "Formulation and Evaluation of Sustained Release Tablets of Losartan Potassium." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 8 number 4 ().
Vancouver S.Rohini Reddy, CH.Shanthi Priya, Dr M Venkata Ramana, M.Praveen, K.Srikanth, G.Srinivas, CH.Vaishnavi, and G.Suchitha. Formulation and Evaluation of Sustained Release Tablets of Losartan Potassium. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2022 [Cited : ]; 8(4) : 378-382. Available from: https://ijariie.com/AdminUploadPdf/Formulation_and_Evaluation_of_Sustained_Release_Tablets_of_Losartan_Potassium_ijariie17697.pdf
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