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Title: :  Design and Development of Atenolol Orally Disintegrating Tablets by Superdisintegration Method
PaperId: :  17699
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 8 Issue 4 2022
DUI:    16.0415/IJARIIE-17699
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Dr Rangu NirmalaSurabhi DayakarRao College of Pharmacy
Dr M Venkata RamanaSurabhi DayakarRao College of Pharmacy
S.Rohini ReddySurabhi DayakarRao College of Pharmacy
N SwethaSurabhi DayakarRao College of Pharmacy
Y Laxmi PrasannaSurabhi DayakarRao College of Pharmacy
N PoojithaSurabhi DayakarRao College of Pharmacy
Sameena KSurabhi DayakarRao College of Pharmacy
Narasimha ReddySurabhi DayakarRao College of Pharmacy

Abstract

Pharmacy
Oro dispersible tablet (ODT), Atenolol, Direct compression, Superdisintegration Method, Anti angina activity.
The present study aims to formulate and evaluate oro dispersible tablets of Atenolol, a drug that is used for the treatment of chest pain (angina) was prepared by using superdisintegration method and also optimize the best formulation. The study involved different excipients which were tested for their compatibility with Atenolol by the FT-IR studies. Based on the results of FT-IR studies, majority of the excipients were found to be compatible with Atenolol which were used for the preparation of Atenolol oral disintegrating tablets. Oral disintegrating tablets of Atenolol were prepared by direct compression method by the addition of super disintegrants. Seven batches (F1 – F7) of oral disintegrating tablets of Atenolol were prepared by using super disintegrants like Sodium starch glycolate and Croscarmellose in variable concentrations along with other excipients for the development of optimized formulation. All the formulations were subjected to evaluation studies of weight variation, hardness, friability, drug content, Wetting time, in-vitro disintegration, in vitro-dissolution studies and are found to be within the limits.

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IJARIIE Dr Rangu Nirmala, Dr M Venkata Ramana, S.Rohini Reddy, N Swetha, Y Laxmi Prasanna, N Poojitha, Sameena K, and Narasimha Reddy. "Design and Development of Atenolol Orally Disintegrating Tablets by Superdisintegration Method" International Journal Of Advance Research And Innovative Ideas In Education Volume 8 Issue 4 2022 Page 370-377
MLA Dr Rangu Nirmala, Dr M Venkata Ramana, S.Rohini Reddy, N Swetha, Y Laxmi Prasanna, N Poojitha, Sameena K, and Narasimha Reddy. "Design and Development of Atenolol Orally Disintegrating Tablets by Superdisintegration Method." International Journal Of Advance Research And Innovative Ideas In Education 8.4(2022) : 370-377.
APA Dr Rangu Nirmala, Dr M Venkata Ramana, S.Rohini Reddy, N Swetha, Y Laxmi Prasanna, N Poojitha, Sameena K, & Narasimha Reddy. (2022). Design and Development of Atenolol Orally Disintegrating Tablets by Superdisintegration Method. International Journal Of Advance Research And Innovative Ideas In Education, 8(4), 370-377.
Chicago Dr Rangu Nirmala, Dr M Venkata Ramana, S.Rohini Reddy, N Swetha, Y Laxmi Prasanna, N Poojitha, Sameena K, and Narasimha Reddy. "Design and Development of Atenolol Orally Disintegrating Tablets by Superdisintegration Method." International Journal Of Advance Research And Innovative Ideas In Education 8, no. 4 (2022) : 370-377.
Oxford Dr Rangu Nirmala, Dr M Venkata Ramana, S.Rohini Reddy, N Swetha, Y Laxmi Prasanna, N Poojitha, Sameena K, and Narasimha Reddy. 'Design and Development of Atenolol Orally Disintegrating Tablets by Superdisintegration Method', International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 4, 2022, p. 370-377. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Design_and_Development_of_Atenolol_Orally_Disintegrating_Tablets_by_Superdisintegration_Method_ijariie17699.pdf (Accessed : ).
Harvard Dr Rangu Nirmala, Dr M Venkata Ramana, S.Rohini Reddy, N Swetha, Y Laxmi Prasanna, N Poojitha, Sameena K, and Narasimha Reddy. (2022) 'Design and Development of Atenolol Orally Disintegrating Tablets by Superdisintegration Method', International Journal Of Advance Research And Innovative Ideas In Education, 8(4), pp. 370-377IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Design_and_Development_of_Atenolol_Orally_Disintegrating_Tablets_by_Superdisintegration_Method_ijariie17699.pdf (Accessed : )
IEEE Dr Rangu Nirmala, Dr M Venkata Ramana, S.Rohini Reddy, N Swetha, Y Laxmi Prasanna, N Poojitha, Sameena K, and Narasimha Reddy, "Design and Development of Atenolol Orally Disintegrating Tablets by Superdisintegration Method," International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 4, pp. 370-377, Jul-Aug 2022. [Online]. Available: https://ijariie.com/AdminUploadPdf/Design_and_Development_of_Atenolol_Orally_Disintegrating_Tablets_by_Superdisintegration_Method_ijariie17699.pdf [Accessed : ].
Turabian Dr Rangu Nirmala, Dr M Venkata Ramana, S.Rohini Reddy, N Swetha, Y Laxmi Prasanna, N Poojitha, Sameena K, and Narasimha Reddy. "Design and Development of Atenolol Orally Disintegrating Tablets by Superdisintegration Method." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 8 number 4 ().
Vancouver Dr Rangu Nirmala, Dr M Venkata Ramana, S.Rohini Reddy, N Swetha, Y Laxmi Prasanna, N Poojitha, Sameena K, and Narasimha Reddy. Design and Development of Atenolol Orally Disintegrating Tablets by Superdisintegration Method. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2022 [Cited : ]; 8(4) : 370-377. Available from: https://ijariie.com/AdminUploadPdf/Design_and_Development_of_Atenolol_Orally_Disintegrating_Tablets_by_Superdisintegration_Method_ijariie17699.pdf
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