Call for Papers:Vol.10 Issue.6

Submission
Last date		 30-Dec-2024
Acceptance Status In One Day
Paper Publish In Two Days
Submit ManuScript

News & Updates

Submit Article

Dear Authors, Article publish in our journal for Volume-10,Issue-6. For article submission on below link: Submit Manuscript


Join As Board

Dear Reviewer, You can join our Reviewer team without given any charges in our journal. Submit Details on below link: Join As Board


Paper Publication Charges

IJARIIE APP
Download Android App

For Authors

Archives

IJARIIE Board

Downloads

Android App

Download IJARIIE APP

Authors

Title: :  DEVELOPMENT AND IN VITRO CHARACTERIZATION OF CLARITHROMYCIN MICROSPHERES
PaperId: :  17741
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 8 Issue 4 2022
DUI:    16.0415/IJARIIE-17741
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
A Sneha Surabhi Dayakar Rao College of Pharmacy, Rimmanaguda (V), Gajwel (M), Siddipet (D), Telangana (state) 50231, India
V Kavitha Surabhi Dayakar Rao College of Pharmacy, Rimmanaguda (V), Gajwel (M), Siddipet (D), Telangana (state) 50231, India
Shafiya begumSurabhi Dayakar Rao College of Pharmacy, Rimmanaguda (V), Gajwel (M), Siddipet (D), Telangana (state) 50231, India
Samreen begum Surabhi Dayakar Rao College of Pharmacy, Rimmanaguda (V), Gajwel (M), Siddipet (D), Telangana (state) 50231, India
J Bikshapahi Surabhi Dayakar Rao College of Pharmacy, Rimmanaguda (V), Gajwel (M), Siddipet (D), Telangana (state) 50231, India
B Krishnaveni Surabhi Dayakar Rao College of Pharmacy, Rimmanaguda (V), Gajwel (M), Siddipet (D), Telangana (state) 50231, India

Abstract

PHARMACEUTICAL SCIENCES
Clarithromycin ,HPMC ,Microspheres, Bio adhesive
In the present work, bioadhesive microspheres of Clarithromycin using Sodium alginate along with HPMCK100M, HPMCK15M, as copolymers were formulated to deliver Clarithromycin via oral route. The results of this investigation indicate that ionic cross linking technique Ionotropic gelation method can be successfully employed to fabricate Clarithromycin microspheres. The technique provides characteristic advantage over conventional microsphere method, which involves an “all-aqueous” system, avoids residual solvents in microspheres. Other methods utilize larger volume of organic solvents, which are costly and hazardous because of the possible explosion, air pollution, toxicity and difficult to remove traces of organic solvent completely. Micromeritic studies revealed that the mean particle size of the prepared microspheres was in the size range of 512-903µm and are suitable for bioadhesive microspheres for oral administration.Increase in the polymer concentration led to increase in % Yield, % Drug entrapment efficiency, Particle size, % swelling and % Mucoadhesion.The in-vitro mucoadhesive study demonstrated that microspheres of Clarithromycin using sodium alginate along with HPMCK15M as copolymer adhered to the mucus to a greater extent than the microspheres of Clarithromycin using sodium alginate along with HPMCK100M as copolymer.

Citations

Copy and paste a formatted citation or use one of the links to import into a bibliography manager and reference.

IJARIIE A Sneha, V Kavitha, Shafiya begum, Samreen begum, J Bikshapahi, and B Krishnaveni. "DEVELOPMENT AND IN VITRO CHARACTERIZATION OF CLARITHROMYCIN MICROSPHERES" International Journal Of Advance Research And Innovative Ideas In Education Volume 8 Issue 4 2022 Page 873-879
MLA A Sneha, V Kavitha, Shafiya begum, Samreen begum, J Bikshapahi, and B Krishnaveni. "DEVELOPMENT AND IN VITRO CHARACTERIZATION OF CLARITHROMYCIN MICROSPHERES." International Journal Of Advance Research And Innovative Ideas In Education 8.4(2022) : 873-879.
APA A Sneha, V Kavitha, Shafiya begum, Samreen begum, J Bikshapahi, & B Krishnaveni. (2022). DEVELOPMENT AND IN VITRO CHARACTERIZATION OF CLARITHROMYCIN MICROSPHERES. International Journal Of Advance Research And Innovative Ideas In Education, 8(4), 873-879.
Chicago A Sneha, V Kavitha, Shafiya begum, Samreen begum, J Bikshapahi, and B Krishnaveni. "DEVELOPMENT AND IN VITRO CHARACTERIZATION OF CLARITHROMYCIN MICROSPHERES." International Journal Of Advance Research And Innovative Ideas In Education 8, no. 4 (2022) : 873-879.
Oxford A Sneha, V Kavitha, Shafiya begum, Samreen begum, J Bikshapahi, and B Krishnaveni. 'DEVELOPMENT AND IN VITRO CHARACTERIZATION OF CLARITHROMYCIN MICROSPHERES', International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 4, 2022, p. 873-879. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_IN_VITRO_CHARACTERIZATION_OF_CLARITHROMYCIN_MICROSPHERES_ijariie17741.pdf (Accessed : ).
Harvard A Sneha, V Kavitha, Shafiya begum, Samreen begum, J Bikshapahi, and B Krishnaveni. (2022) 'DEVELOPMENT AND IN VITRO CHARACTERIZATION OF CLARITHROMYCIN MICROSPHERES', International Journal Of Advance Research And Innovative Ideas In Education, 8(4), pp. 873-879IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_IN_VITRO_CHARACTERIZATION_OF_CLARITHROMYCIN_MICROSPHERES_ijariie17741.pdf (Accessed : )
IEEE A Sneha, V Kavitha, Shafiya begum, Samreen begum, J Bikshapahi, and B Krishnaveni, "DEVELOPMENT AND IN VITRO CHARACTERIZATION OF CLARITHROMYCIN MICROSPHERES," International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 4, pp. 873-879, Jul-Aug 2022. [Online]. Available: https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_IN_VITRO_CHARACTERIZATION_OF_CLARITHROMYCIN_MICROSPHERES_ijariie17741.pdf [Accessed : ].
Turabian A Sneha, V Kavitha, Shafiya begum, Samreen begum, J Bikshapahi, and B Krishnaveni. "DEVELOPMENT AND IN VITRO CHARACTERIZATION OF CLARITHROMYCIN MICROSPHERES." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 8 number 4 ().
Vancouver A Sneha, V Kavitha, Shafiya begum, Samreen begum, J Bikshapahi, and B Krishnaveni. DEVELOPMENT AND IN VITRO CHARACTERIZATION OF CLARITHROMYCIN MICROSPHERES. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2022 [Cited : ]; 8(4) : 873-879. Available from: https://ijariie.com/AdminUploadPdf/DEVELOPMENT_AND_IN_VITRO_CHARACTERIZATION_OF_CLARITHROMYCIN_MICROSPHERES_ijariie17741.pdf
BibTex EndNote RefMan RefWorks

Number Of Downloads



Save in Google Drive

Similar-Paper

TitleArea of ResearchAuther NameAction
A comprehensive review on Flaxseeds: Nutritional profile, food uses and health benefitsPharmacyMs. Samruddhi Rajpure Download
A comprehensive review on Enicostemma Littorale Blume as an Ayurvedic HerbPharmacyMr. Prasad Bhopale Download
REVIEW ON SHANKHPUSHPI IN NEUROLOGICAL DISORDERSpharmacognosyAbhilash Kutlehria Download
"MARFAN SYNDROME: A COMPREHENSIVE GUIDE TO PATHOGENESIS, DIAGNOSIS, TREATMENT AND MEDICAL MANAGEMENT"Pharmacy Vishvajit Bharat Waghmare Download
To Study On Etiology, Symptoms, Diagnosis ,Treatment and Therapeutic Outcome Of ‘DENGUE FEVER’PHARMACYMELAM.YESURATNAM Download
A review on Nutritional requirements during pregnancyPharmacy Rode Nikita Shivaji Download
DEVELOPMENT AND CHARACTERIZATION OF ORAL MICRO-PARTICULATE DRUG DELIVERY SYSTEMPharmacyAbhilashkutlehria Download
Composition and Analyzation of Transdermal Diclofenac Sodium PatchesPharmacyAbhilash Kutlehria Download
A REVIEW ON HERBAL MEDICINE PLANTS ARE USED FOR THE TREATMENT OF EYE DISORDERS.PHARMACYManoj AN Download
Validation of Sitagliptin Phosphate & Simvastatin by RP-HPLCPharmaceutical Science Sahil Ravindra Chavhan Download
Method Development and Validation of Kaempferol by using High Performance Liquid ChromatographyPharmacyReena Nanasaheb Autade Download
Cheilocostus Speciosus Traditional Uses And TaxonomyPharmacyRajat Kumar Download
Evaluation of Medicinal Plants for Their Therapeutic Potential in Wound ManagementM. Pharmacy (Pharmacology)Aniket Dhadwal Download
A PROSPECTIVE REVIEW ON TRANSETHASOMAL GEL AS CARRIER FOR ENHANCING TRANSDERMAL DELIVERYPharmaceutical FormulationMohammad amin Yatoo Download
FORMULATION AND EVALUATION OF POLY HERBAL FACE MASKpharmacyVANASHRI TURKE Download
12