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Title: :  A Review on Design and Development of Rivaroxaban Tablet and Comparative Dissolution Profiling
PaperId: :  18182
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 8 Issue 5 2022
DUI:    16.0415/IJARIIE-18182
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Pankaj Kumar ChauhanDepartment of Pharmacy, M. pharma (Pharmaceutics), GRD(PG)IMT, Dehradun, Uttarakhand

Abstract

Department of Pharmacy, M. pharma (Pharmaceutics), GRD(PG)IMT, Dehradun, Uttarakhand
Rivaroxaban tablet, Xarex tablet (Market product), Dissolution profile comparison. comparative studies of in-vitro dissolution, Dissolution apparatus USP type-II, UV spectrophotometer technique.
The aim of present study is design and development of Rivaroxaban table and comparative dissolution profile in other development formulation. Dissolution testing is an in vitro technique of great importance in formulation and development of pharmaceutical dosage forms. The main objective of the present study is to conduct the comparative dissolution studies of various brands of same dosage forms and treatment of obtained dissolution data by using Graphical technique whether all the formulations used were equivalent. Rivaroxaban 10 mg tablet (In-House product) and Rivaroxaban Tablets 10 mg (Xarex 10) (Market sample) from different manufacturers were used in the study, and dissolution testing in different dissolution media 0.1 N HCl solution, phosphate buffer of pH 4.5 and phosphate buffer of pH 6.8 was conducted for 6 tablets from each brand for 60 min. by using dissolution testing apparatus USP type-II., 50rpm, 37±0.5 temperature and used 900 ml media. Samples were withdrawn at 5, 15, 30, 45 and 60 minutes and 50. time interval and analyzed for drug content by using UV spectrophotometer technique and used UV detector 250 nm. Percent drug release at each time interval was calculated for tablets and the data obtained were treated with Graphical technique.

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IJARIIE Pankaj Kumar Chauhan. "A Review on Design and Development of Rivaroxaban Tablet and Comparative Dissolution Profiling" International Journal Of Advance Research And Innovative Ideas In Education Volume 8 Issue 5 2022 Page 303-313
MLA Pankaj Kumar Chauhan. "A Review on Design and Development of Rivaroxaban Tablet and Comparative Dissolution Profiling." International Journal Of Advance Research And Innovative Ideas In Education 8.5(2022) : 303-313.
APA Pankaj Kumar Chauhan. (2022). A Review on Design and Development of Rivaroxaban Tablet and Comparative Dissolution Profiling. International Journal Of Advance Research And Innovative Ideas In Education, 8(5), 303-313.
Chicago Pankaj Kumar Chauhan. "A Review on Design and Development of Rivaroxaban Tablet and Comparative Dissolution Profiling." International Journal Of Advance Research And Innovative Ideas In Education 8, no. 5 (2022) : 303-313.
Oxford Pankaj Kumar Chauhan. 'A Review on Design and Development of Rivaroxaban Tablet and Comparative Dissolution Profiling', International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 5, 2022, p. 303-313. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/A_Review_on_Design_and_Development_of_Rivaroxaban_Tablet_and_Comparative_Dissolution_Profiling_ijariie18182.pdf (Accessed : ).
Harvard Pankaj Kumar Chauhan. (2022) 'A Review on Design and Development of Rivaroxaban Tablet and Comparative Dissolution Profiling', International Journal Of Advance Research And Innovative Ideas In Education, 8(5), pp. 303-313IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/A_Review_on_Design_and_Development_of_Rivaroxaban_Tablet_and_Comparative_Dissolution_Profiling_ijariie18182.pdf (Accessed : )
IEEE Pankaj Kumar Chauhan, "A Review on Design and Development of Rivaroxaban Tablet and Comparative Dissolution Profiling," International Journal Of Advance Research And Innovative Ideas In Education, vol. 8, no. 5, pp. 303-313, Sep-Oct 2022. [Online]. Available: https://ijariie.com/AdminUploadPdf/A_Review_on_Design_and_Development_of_Rivaroxaban_Tablet_and_Comparative_Dissolution_Profiling_ijariie18182.pdf [Accessed : ].
Turabian Pankaj Kumar Chauhan. "A Review on Design and Development of Rivaroxaban Tablet and Comparative Dissolution Profiling." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 8 number 5 ().
Vancouver Pankaj Kumar Chauhan. A Review on Design and Development of Rivaroxaban Tablet and Comparative Dissolution Profiling. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2022 [Cited : ]; 8(5) : 303-313. Available from: https://ijariie.com/AdminUploadPdf/A_Review_on_Design_and_Development_of_Rivaroxaban_Tablet_and_Comparative_Dissolution_Profiling_ijariie18182.pdf
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A Review on Design and Development of Rivaroxaban Tablet and Comparative Dissolution ProfilingDepartment of Pharmacy, M. pharma (Pharmaceutics), GRD(PG)IMT, Dehradun, UttarakhandPankaj Kumar Chauhan Download