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Title: :  Epidemiology and Prognostic Factors for Viral Hepatitis C in Western Algeria
PaperId: :  19979
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 9 Issue 3 2023
DUI:    16.0415/IJARIIE-19979
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Lakhdar ZEMOURFaculty of medicine of ORAN, epidemiology department of the hospital-university establishment, Oran, Algeria
Amina BELGHITRIFaculty of medicine of ORAN, Pneumology department of the hospital-university establishment, Oran, Algeria
Nassima AmaniFaculty of medicine of ORAN, gastroenterology department of Oran University Hospital Center, Algeria
Nori MIDOUNFaculty of medicine of ORAN, epidemiology department of the hospital-university establishment, Oran, Algeria

Abstract

Biological & Medical Sciences
Hepatitis C Virus, Fibrosis, Cirrhosis, Hepatocellular Carcinoma, Mortality, Cox model
Background: Viral hepatitis C is a major public health problem worldwide. Their magnitude stems from their frequency and their short- and long-term health impact due to their evolutionary potential and therefore their complications. The objective of our work is to establish the epidemiological profile of viral hepatitis C in western Algeria and to identify the main prognostic factors associated with the progression of liver fibrosis. Methods: A cross-sectional descriptive study was carried out in Western Algeria. Information on patients with viral hepatitis C (VHC) was collected prospectively from January 2013 to December 2016. Cox's model was used to model the instant risk logarithm based on a set of predictors predicting the progression of fibrosis over time. The student’s t-test and Analysis of variance (ANOVA) were used for the comparison of continuous variables Results: A population of 594 patients was collected. The sex ratio was 0.65. Metabolic syndrome was found in 16.5%. Severe fibrosis (F3-F4) accounts for 30.3% of VHB cases. 82.1% of patients are divided into G1 and G2 with almost equivalent frequencies of 41.9% and 40.2% respectively. The discovery of viral infection was systematic in 42.6% of cases. The patterns of contamination reported in our study population are represented mainly by care (60.6%) and the use of traditional practices (14.8%) such as hijama, scarification and tattooing. Cirrhosis is found in 30.3% of VHC cases with an average age of 56.3 years. 28.3% of cirrhotics are diabetic. According to Cox's modelling, Hepatocellular Carcinoma and diabetes are prognostic factors of mortality in viral hepatitis C. Conclusion: The most documented mode of contamination in our population, after that related to care, is the use of traditional practices; which could direct us to a population that should not be overlooked in terms of screening and awareness. The predictive factors for cirrhosis were inflammatory activity (A2-A3), age >40 years, diabetes mellitus and use of traditional practices

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IJARIIE Lakhdar ZEMOUR, Amina BELGHITRI, Nassima Amani, and Nori MIDOUN. "Epidemiology and Prognostic Factors for Viral Hepatitis C in Western Algeria" International Journal Of Advance Research And Innovative Ideas In Education Volume 9 Issue 3 2023 Page 258-269
MLA Lakhdar ZEMOUR, Amina BELGHITRI, Nassima Amani, and Nori MIDOUN. "Epidemiology and Prognostic Factors for Viral Hepatitis C in Western Algeria." International Journal Of Advance Research And Innovative Ideas In Education 9.3(2023) : 258-269.
APA Lakhdar ZEMOUR, Amina BELGHITRI, Nassima Amani, & Nori MIDOUN. (2023). Epidemiology and Prognostic Factors for Viral Hepatitis C in Western Algeria. International Journal Of Advance Research And Innovative Ideas In Education, 9(3), 258-269.
Chicago Lakhdar ZEMOUR, Amina BELGHITRI, Nassima Amani, and Nori MIDOUN. "Epidemiology and Prognostic Factors for Viral Hepatitis C in Western Algeria." International Journal Of Advance Research And Innovative Ideas In Education 9, no. 3 (2023) : 258-269.
Oxford Lakhdar ZEMOUR, Amina BELGHITRI, Nassima Amani, and Nori MIDOUN. 'Epidemiology and Prognostic Factors for Viral Hepatitis C in Western Algeria', International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 3, 2023, p. 258-269. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Epidemiology_and_Prognostic_Factors_for_Viral_Hepatitis_C__in_Western_Algeria_ijariie19979.pdf (Accessed : ).
Harvard Lakhdar ZEMOUR, Amina BELGHITRI, Nassima Amani, and Nori MIDOUN. (2023) 'Epidemiology and Prognostic Factors for Viral Hepatitis C in Western Algeria', International Journal Of Advance Research And Innovative Ideas In Education, 9(3), pp. 258-269IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Epidemiology_and_Prognostic_Factors_for_Viral_Hepatitis_C__in_Western_Algeria_ijariie19979.pdf (Accessed : )
IEEE Lakhdar ZEMOUR, Amina BELGHITRI, Nassima Amani, and Nori MIDOUN, "Epidemiology and Prognostic Factors for Viral Hepatitis C in Western Algeria," International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 3, pp. 258-269, May-Jun 2023. [Online]. Available: https://ijariie.com/AdminUploadPdf/Epidemiology_and_Prognostic_Factors_for_Viral_Hepatitis_C__in_Western_Algeria_ijariie19979.pdf [Accessed : ].
Turabian Lakhdar ZEMOUR, Amina BELGHITRI, Nassima Amani, and Nori MIDOUN. "Epidemiology and Prognostic Factors for Viral Hepatitis C in Western Algeria." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 9 number 3 ().
Vancouver Lakhdar ZEMOUR, Amina BELGHITRI, Nassima Amani, and Nori MIDOUN. Epidemiology and Prognostic Factors for Viral Hepatitis C in Western Algeria. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2023 [Cited : ]; 9(3) : 258-269. Available from: https://ijariie.com/AdminUploadPdf/Epidemiology_and_Prognostic_Factors_for_Viral_Hepatitis_C__in_Western_Algeria_ijariie19979.pdf
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