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Title: :  Formulation and Evaluation of Nanosuspension of Antiviral Ophthalmic Application
PaperId: :  20252
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 9 Issue 3 2023
DUI:    16.0415/IJARIIE-20252
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Sejal SonwaneSchool of Pharmacy
Ramakant SharmaSchool of Pharmacy
Shabnam KhanSchool of Pharmacy
Jeevan PatelSchool of Pharmacy
Dr. Rakesh PatelSchool of Pharmacy

Abstract

M. Pharmacy
Nanosuspension, Antiviral ophthalmic application, Acyclovir
Formulation and evaluation of Nanosuspension of Acyclovir for ophthalmic application.In this study, an attempt was made to improve the solubility and dissolution characteristics of a poorly soluble drug (Acyclovir) using nanosuspension technology.To improve the solubility. To formulate and evaluate acyclovir loaded nanosuspension Optimization of formulation and process parameters enhanced corneal residence time.To achieve sufficient drug concentration at absorption site, improve Therapeutic effect and lower dose with better patient compliance. Results conclusively prove that Acyclovir nanosuspension prepared by high speed homogenization method. Different excipients are used in formulation like Poloxamer-188, PVP K-90, different concentrations. F5 batch has shown the better results in high speed homogenization Different excipients were shown variation in particle size, DSC study, drug content, entrapment efficiency and in-vitro dissolution study. Optimized formulation was chosen on the basis of results obtained from particle size and entrapment efficiency. The combination of excipients yields nanosuspension with the smallest average particle size and by the transformation of the nanosuspension into the physical stability of this system could be further enhanced

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IJARIIE Sejal Sonwane, Ramakant Sharma, Shabnam Khan, Jeevan Patel, and Dr. Rakesh Patel. "Formulation and Evaluation of Nanosuspension of Antiviral Ophthalmic Application" International Journal Of Advance Research And Innovative Ideas In Education Volume 9 Issue 3 2023 Page 1394-1403
MLA Sejal Sonwane, Ramakant Sharma, Shabnam Khan, Jeevan Patel, and Dr. Rakesh Patel. "Formulation and Evaluation of Nanosuspension of Antiviral Ophthalmic Application." International Journal Of Advance Research And Innovative Ideas In Education 9.3(2023) : 1394-1403.
APA Sejal Sonwane, Ramakant Sharma, Shabnam Khan, Jeevan Patel, & Dr. Rakesh Patel. (2023). Formulation and Evaluation of Nanosuspension of Antiviral Ophthalmic Application. International Journal Of Advance Research And Innovative Ideas In Education, 9(3), 1394-1403.
Chicago Sejal Sonwane, Ramakant Sharma, Shabnam Khan, Jeevan Patel, and Dr. Rakesh Patel. "Formulation and Evaluation of Nanosuspension of Antiviral Ophthalmic Application." International Journal Of Advance Research And Innovative Ideas In Education 9, no. 3 (2023) : 1394-1403.
Oxford Sejal Sonwane, Ramakant Sharma, Shabnam Khan, Jeevan Patel, and Dr. Rakesh Patel. 'Formulation and Evaluation of Nanosuspension of Antiviral Ophthalmic Application', International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 3, 2023, p. 1394-1403. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Formulation_and_Evaluation_of_Nanosuspension_of_Antiviral_Ophthalmic_Application_ijariie20252.pdf (Accessed : ).
Harvard Sejal Sonwane, Ramakant Sharma, Shabnam Khan, Jeevan Patel, and Dr. Rakesh Patel. (2023) 'Formulation and Evaluation of Nanosuspension of Antiviral Ophthalmic Application', International Journal Of Advance Research And Innovative Ideas In Education, 9(3), pp. 1394-1403IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Formulation_and_Evaluation_of_Nanosuspension_of_Antiviral_Ophthalmic_Application_ijariie20252.pdf (Accessed : )
IEEE Sejal Sonwane, Ramakant Sharma, Shabnam Khan, Jeevan Patel, and Dr. Rakesh Patel, "Formulation and Evaluation of Nanosuspension of Antiviral Ophthalmic Application," International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 3, pp. 1394-1403, May-Jun 2023. [Online]. Available: https://ijariie.com/AdminUploadPdf/Formulation_and_Evaluation_of_Nanosuspension_of_Antiviral_Ophthalmic_Application_ijariie20252.pdf [Accessed : ].
Turabian Sejal Sonwane, Ramakant Sharma, Shabnam Khan, Jeevan Patel, and Dr. Rakesh Patel. "Formulation and Evaluation of Nanosuspension of Antiviral Ophthalmic Application." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 9 number 3 ().
Vancouver Sejal Sonwane, Ramakant Sharma, Shabnam Khan, Jeevan Patel, and Dr. Rakesh Patel. Formulation and Evaluation of Nanosuspension of Antiviral Ophthalmic Application. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2023 [Cited : ]; 9(3) : 1394-1403. Available from: https://ijariie.com/AdminUploadPdf/Formulation_and_Evaluation_of_Nanosuspension_of_Antiviral_Ophthalmic_Application_ijariie20252.pdf
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