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Title: :  FORMULATION AND IN-VITRO EVALUATION OF BENZOATE ANTI-TUSSIVE SYRUP
PaperId: :  20805
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 9 Issue 3 2023
DUI:    16.0415/IJARIIE-20805
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Dr R NirmalaSurabhi Dayakar Rao College of Pharmacy
Harshitha USurabhi Dayakar Rao College of Pharmacy
SridharSurabhi Dayakar Rao College of Pharmacy
MamathaSurabhi Dayakar Rao College of Pharmacy
SangeethaSurabhi Dayakar Rao College of Pharmacy
Kavya sriSurabhi Dayakar Rao College of Pharmacy
jairamSurabhi Dayakar Rao College of Pharmacy

Abstract

Pharmacy
Syrup, Anti-tussive, Cough, Benzoate
Cough is a common symptom associated with various respiratory conditions and can significantly affect a person's quality of life. Antitussive syrups are widely used to relieve cough and provide symptomatic relief. In this study, we aimed to formulate and evaluate a benzoate antitussive syrup to assess its effectiveness in suppressing cough. The benzoate antitussive syrup was formulated using a combination of active ingredients known for their cough-suppressing properties. The syrup was prepared using a suitable vehicle and optimized for taste, viscosity, and stability. Various physicochemical parameters, including pH, density, and viscosity, were determined to ensure the syrup's compliance with pharmaceutical standards. Furthermore, the antitussive activity of the formulated syrup was evaluated using an appropriate animal model of cough. The animals were administered the benzoate antitussive syrup orally, and their cough response was assessed using established cough models. The antitussive efficacy was compared against a placebo group to determine the effectiveness of the formulated syrup in suppressing cough. The evaluation of the benzoate antitussive syrup included the assessment of safety and tolerability. Acute toxicity studies were conducted to determine the safety profile of the syrup, and potential adverse effects were monitored. The results of this study demonstrated the successful formulation of a benzoate antitussive syrup with favorable physicochemical properties. The syrup exhibited significant antitussive activity, effectively suppressing cough in the animal model. Safety evaluation revealed no significant acute toxicity or adverse effects associated with the syrup. Overall, the formulation and evaluation of the benzoate antitussive syrup showed promising results, suggesting its potential as an effective and safe option for the management of cough. Further studies, including clinical trials, are warranted to validate its efficacy and safety in humans and to explore its potential as a therapeutic option for cough relief.

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IJARIIE Dr R Nirmala, Harshitha U, Sridhar, Mamatha, Sangeetha, Kavya sri, and jairam. "FORMULATION AND IN-VITRO EVALUATION OF BENZOATE ANTI-TUSSIVE SYRUP" International Journal Of Advance Research And Innovative Ideas In Education Volume 9 Issue 3 2023 Page 4029-4034
MLA Dr R Nirmala, Harshitha U, Sridhar, Mamatha, Sangeetha, Kavya sri, and jairam. "FORMULATION AND IN-VITRO EVALUATION OF BENZOATE ANTI-TUSSIVE SYRUP." International Journal Of Advance Research And Innovative Ideas In Education 9.3(2023) : 4029-4034.
APA Dr R Nirmala, Harshitha U, Sridhar, Mamatha, Sangeetha, Kavya sri, & jairam. (2023). FORMULATION AND IN-VITRO EVALUATION OF BENZOATE ANTI-TUSSIVE SYRUP. International Journal Of Advance Research And Innovative Ideas In Education, 9(3), 4029-4034.
Chicago Dr R Nirmala, Harshitha U, Sridhar, Mamatha, Sangeetha, Kavya sri, and jairam. "FORMULATION AND IN-VITRO EVALUATION OF BENZOATE ANTI-TUSSIVE SYRUP." International Journal Of Advance Research And Innovative Ideas In Education 9, no. 3 (2023) : 4029-4034.
Oxford Dr R Nirmala, Harshitha U, Sridhar, Mamatha, Sangeetha, Kavya sri, and jairam. 'FORMULATION AND IN-VITRO EVALUATION OF BENZOATE ANTI-TUSSIVE SYRUP', International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 3, 2023, p. 4029-4034. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/FORMULATION_AND_IN_VITRO_EVALUATION_OF_BENZOATE__ANTI_TUSSIVE_SYRUP_ijariie20805.pdf (Accessed : ).
Harvard Dr R Nirmala, Harshitha U, Sridhar, Mamatha, Sangeetha, Kavya sri, and jairam. (2023) 'FORMULATION AND IN-VITRO EVALUATION OF BENZOATE ANTI-TUSSIVE SYRUP', International Journal Of Advance Research And Innovative Ideas In Education, 9(3), pp. 4029-4034IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/FORMULATION_AND_IN_VITRO_EVALUATION_OF_BENZOATE__ANTI_TUSSIVE_SYRUP_ijariie20805.pdf (Accessed : )
IEEE Dr R Nirmala, Harshitha U, Sridhar, Mamatha, Sangeetha, Kavya sri, and jairam, "FORMULATION AND IN-VITRO EVALUATION OF BENZOATE ANTI-TUSSIVE SYRUP," International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 3, pp. 4029-4034, May-Jun 2023. [Online]. Available: https://ijariie.com/AdminUploadPdf/FORMULATION_AND_IN_VITRO_EVALUATION_OF_BENZOATE__ANTI_TUSSIVE_SYRUP_ijariie20805.pdf [Accessed : ].
Turabian Dr R Nirmala, Harshitha U, Sridhar, Mamatha, Sangeetha, Kavya sri, and jairam. "FORMULATION AND IN-VITRO EVALUATION OF BENZOATE ANTI-TUSSIVE SYRUP." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 9 number 3 ().
Vancouver Dr R Nirmala, Harshitha U, Sridhar, Mamatha, Sangeetha, Kavya sri, and jairam. FORMULATION AND IN-VITRO EVALUATION OF BENZOATE ANTI-TUSSIVE SYRUP. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2023 [Cited : ]; 9(3) : 4029-4034. Available from: https://ijariie.com/AdminUploadPdf/FORMULATION_AND_IN_VITRO_EVALUATION_OF_BENZOATE__ANTI_TUSSIVE_SYRUP_ijariie20805.pdf
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