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Title: :  “Formulation and evaluation of nanosuspension of valsartan’’
PaperId: :  20950
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 9 Issue 3 2023
DUI:    16.0415/IJARIIE-20950
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Sunil Chadoker School of Pharmacy
shabnam khan School of Pharmacy
ramakant sharmaSchool of Pharmacy
jeevan patel School of Pharmacy
dr rakesh patel School of Pharmacy

Abstract

M. Pharmacy
Nanosuspension, valsartan, solubilization, Hpertension
Valsartan is a new potent and orally active solubilization which selectivity act as angiotensin II antagonist acting on the AT1 receptor subtype. It is indicated for hypertension, heart failure and post-myocardial infarction It is a poorly aqueous soluble drug (BCS Class II), and is being selected for the enhancement of solubility and bioavailability.The major problem in oral drug formulations is low and erratic bioavailability, which mainly results from poor aqueous solubility.The drug is having low aqueous solubility of about 0.0213mg/ml.The drug is rapidly absorbed after oral administration having bioavailability is 23%.This compound belongs to the class of organic compounds known as biphenyltetrazoles and derivatives. These are organic compounds containing a biphenyl attached to a tetrazole. A carbon atom of the biphenyl moiety is boned to a carbon or the nitrogen atom of the tetrazole moiety.There are many conventional methods for increasing the solubility of poorly soluble drugs, which include micronization, solubilization using co-solvents, salt form, surfactant dispersions, precipitation technique, and oily solution.Other techniques are like liposomes, emulsions, microemulsion, solid dispersion and inclusion complexation using cyclodextrins show sensible achiever, but they lack in universal applicability to all drugs. These techniques are not applicable for those drugs which are not soluble in aqueous and organic solvents.

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IJARIIE Sunil Chadoker , shabnam khan , ramakant sharma, jeevan patel , and dr rakesh patel . "“Formulation and evaluation of nanosuspension of valsartan’’" International Journal Of Advance Research And Innovative Ideas In Education Volume 9 Issue 3 2023 Page 4885-4895
MLA Sunil Chadoker , shabnam khan , ramakant sharma, jeevan patel , and dr rakesh patel . "“Formulation and evaluation of nanosuspension of valsartan’’." International Journal Of Advance Research And Innovative Ideas In Education 9.3(2023) : 4885-4895.
APA Sunil Chadoker , shabnam khan , ramakant sharma, jeevan patel , & dr rakesh patel . (2023). “Formulation and evaluation of nanosuspension of valsartan’’. International Journal Of Advance Research And Innovative Ideas In Education, 9(3), 4885-4895.
Chicago Sunil Chadoker , shabnam khan , ramakant sharma, jeevan patel , and dr rakesh patel . "“Formulation and evaluation of nanosuspension of valsartan’’." International Journal Of Advance Research And Innovative Ideas In Education 9, no. 3 (2023) : 4885-4895.
Oxford Sunil Chadoker , shabnam khan , ramakant sharma, jeevan patel , and dr rakesh patel . '“Formulation and evaluation of nanosuspension of valsartan’’', International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 3, 2023, p. 4885-4895. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/“Formulation_and_evaluation_of_nanosuspension_of_valsartan’’_ijariie20950.pdf (Accessed : ).
Harvard Sunil Chadoker , shabnam khan , ramakant sharma, jeevan patel , and dr rakesh patel . (2023) '“Formulation and evaluation of nanosuspension of valsartan’’', International Journal Of Advance Research And Innovative Ideas In Education, 9(3), pp. 4885-4895IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/“Formulation_and_evaluation_of_nanosuspension_of_valsartan’’_ijariie20950.pdf (Accessed : )
IEEE Sunil Chadoker , shabnam khan , ramakant sharma, jeevan patel , and dr rakesh patel , "“Formulation and evaluation of nanosuspension of valsartan’’," International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 3, pp. 4885-4895, May-Jun 2023. [Online]. Available: https://ijariie.com/AdminUploadPdf/“Formulation_and_evaluation_of_nanosuspension_of_valsartan’’_ijariie20950.pdf [Accessed : ].
Turabian Sunil Chadoker , shabnam khan , ramakant sharma, jeevan patel , and dr rakesh patel . "“Formulation and evaluation of nanosuspension of valsartan’’." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 9 number 3 ().
Vancouver Sunil Chadoker , shabnam khan , ramakant sharma, jeevan patel , and dr rakesh patel . “Formulation and evaluation of nanosuspension of valsartan’’. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2023 [Cited : ]; 9(3) : 4885-4895. Available from: https://ijariie.com/AdminUploadPdf/“Formulation_and_evaluation_of_nanosuspension_of_valsartan’’_ijariie20950.pdf
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