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Title: :  PHARMACOLOGICAL AND THERAPEUTIC USE OF FUROSEMIDE IN THE MANAGEMENT OF HYPERTENSION
PaperId: :  21525
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 9 Issue 5 2023
DUI:    16.0415/IJARIIE-21525
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Nitesh DubeyShambhunath Institute of Pharmacy, Jhalwa, Prayagraj
Ritika SinghNand Kishore College of Pharmacy, Prayagraj
Yashwant SinghNand Kishore College of Pharmacy, Prayagraj
Nusrat JahanShambhunath Institute of Pharmacy, Jhalwa, Prayagraj
Rishabh Kumar ChandraShambhunath Institute of Pharmacy, Jhalwa, Prayagraj

Abstract

pharmacy
Hypertension, Cardiovascular health, Furosemide, Loop diuretic, Reabsorption, Ascending Loop of Henle, Intravascular volume, Peripheral resistance, RAAS, Blood pressure
The management of hypertension presents a critical challenge in modern healthcare due to its profound implications for cardiovascular health. This review article delves into the pharmacological and therapeutic utilization of Furosemide in the context of hypertension management. Furosemide, a potent loop diuretic, operates by inhibiting sodium and chloride reabsorption in the ascending loop of Henle, resulting in augmented urinary excretion of electrolytes and fluid. This diuretic action leads to a reduction in intravascular volume, subsequently lowering cardiac output and peripheral resistance, which collectively contribute to blood pressure reduction. The article comprehensively examines the mechanism of action of furosemide and its intricate interaction with the renin-angiotensin-aldosterone system (RAAS), pivotal in sodium and fluid balance regulation. Clinical trials affirm the efficacy of furosemide in decreasing blood pressure in hypertensive patients. Additionally, its role in combination therapy with other antihypertensive agents underscores its significance as an adjunct treatment strategy. Beyond hypertension, furosemide's relevance extends to managing edema associated with cardiac and renal disorders. However, the review also acknowledges potential challenges, including adverse effects such as electrolyte imbalances and dehydration, which necessitate vigilant monitoring and individualized dosing strategies. The abstract concludes by emphasizing the evolving landscape of furosemide-based therapies, accentuating the need for personalized approaches and ongoing research in the pursuit of optimal hypertension management.

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IJARIIE Nitesh Dubey, Ritika Singh, Yashwant Singh, Nusrat Jahan, and Rishabh Kumar Chandra. "PHARMACOLOGICAL AND THERAPEUTIC USE OF FUROSEMIDE IN THE MANAGEMENT OF HYPERTENSION" International Journal Of Advance Research And Innovative Ideas In Education Volume 9 Issue 5 2023 Page 64-68
MLA Nitesh Dubey, Ritika Singh, Yashwant Singh, Nusrat Jahan, and Rishabh Kumar Chandra. "PHARMACOLOGICAL AND THERAPEUTIC USE OF FUROSEMIDE IN THE MANAGEMENT OF HYPERTENSION." International Journal Of Advance Research And Innovative Ideas In Education 9.5(2023) : 64-68.
APA Nitesh Dubey, Ritika Singh, Yashwant Singh, Nusrat Jahan, & Rishabh Kumar Chandra. (2023). PHARMACOLOGICAL AND THERAPEUTIC USE OF FUROSEMIDE IN THE MANAGEMENT OF HYPERTENSION. International Journal Of Advance Research And Innovative Ideas In Education, 9(5), 64-68.
Chicago Nitesh Dubey, Ritika Singh, Yashwant Singh, Nusrat Jahan, and Rishabh Kumar Chandra. "PHARMACOLOGICAL AND THERAPEUTIC USE OF FUROSEMIDE IN THE MANAGEMENT OF HYPERTENSION." International Journal Of Advance Research And Innovative Ideas In Education 9, no. 5 (2023) : 64-68.
Oxford Nitesh Dubey, Ritika Singh, Yashwant Singh, Nusrat Jahan, and Rishabh Kumar Chandra. 'PHARMACOLOGICAL AND THERAPEUTIC USE OF FUROSEMIDE IN THE MANAGEMENT OF HYPERTENSION', International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 5, 2023, p. 64-68. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/PHARMACOLOGICAL_AND_THERAPEUTIC_USE_OF_FUROSEMIDE_IN_THE_MANAGEMENT_OF_HYPERTENSION_ijariie21525.pdf (Accessed : 09 September 2023).
Harvard Nitesh Dubey, Ritika Singh, Yashwant Singh, Nusrat Jahan, and Rishabh Kumar Chandra. (2023) 'PHARMACOLOGICAL AND THERAPEUTIC USE OF FUROSEMIDE IN THE MANAGEMENT OF HYPERTENSION', International Journal Of Advance Research And Innovative Ideas In Education, 9(5), pp. 64-68IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/PHARMACOLOGICAL_AND_THERAPEUTIC_USE_OF_FUROSEMIDE_IN_THE_MANAGEMENT_OF_HYPERTENSION_ijariie21525.pdf (Accessed : 09 September 2023)
IEEE Nitesh Dubey, Ritika Singh, Yashwant Singh, Nusrat Jahan, and Rishabh Kumar Chandra, "PHARMACOLOGICAL AND THERAPEUTIC USE OF FUROSEMIDE IN THE MANAGEMENT OF HYPERTENSION," International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 5, pp. 64-68, Sep-Oct 2023. [Online]. Available: https://ijariie.com/AdminUploadPdf/PHARMACOLOGICAL_AND_THERAPEUTIC_USE_OF_FUROSEMIDE_IN_THE_MANAGEMENT_OF_HYPERTENSION_ijariie21525.pdf [Accessed : 09 September 2023].
Turabian Nitesh Dubey, Ritika Singh, Yashwant Singh, Nusrat Jahan, and Rishabh Kumar Chandra. "PHARMACOLOGICAL AND THERAPEUTIC USE OF FUROSEMIDE IN THE MANAGEMENT OF HYPERTENSION." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 9 number 5 (09 September 2023).
Vancouver Nitesh Dubey, Ritika Singh, Yashwant Singh, Nusrat Jahan, and Rishabh Kumar Chandra. PHARMACOLOGICAL AND THERAPEUTIC USE OF FUROSEMIDE IN THE MANAGEMENT OF HYPERTENSION. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2023 [Cited : 09 September 2023]; 9(5) : 64-68. Available from: https://ijariie.com/AdminUploadPdf/PHARMACOLOGICAL_AND_THERAPEUTIC_USE_OF_FUROSEMIDE_IN_THE_MANAGEMENT_OF_HYPERTENSION_ijariie21525.pdf
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