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Title: :  Phytochemical, Antioxidant and Hepatoprotective Activity of Parkia biglobosa Husk Methanol Extract in Albino Rats.
PaperId: :  21646
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 9 Issue 5 2023
DUI:    16.0415/IJARIIE-21646
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Shafiu Shehu AnkaDepartment of Chemical Pathology and Immunology (CHS) Usmanu Danfodiyo University Sokoto, Nigeria.
Jude NwaoguDepartment of Biochemistry, Kebbi State University of Science and Technology Aleiro, Kebbi State, Nigeria.
Nura Muhammad AhmadBiological Science Department, College of Education Maru, Zamfara State, Nigeria.
Abdulkarim AbbaDepartment of Biochemistry, Kebbi State University of Science and Technology Aleiro, Kebbi State, Nigeria.

Abstract

Biochemistry
Keyword: Parkia biglobosa, husk, antioxidants, and hepatoprotective
Abstract Medicinal plants are used in almost every part of world to treat illnesses. Oxidative stresses are known to cause damage to living system of humans and animals.This study assessed the determination of phytochemical constituents present in Parkia biglobosa husk, antioxidants and hepatoprotective effect of husk methanol extract on rats .The phytochemical property of methanol extract was determined using standard methods. The phytochemical screening of the husk methanol extract revealed the presence of alkaloid, saponins, tannins, flavonoids, steroids and glycosides. The quantitative phytochemical analysis revealed high content of tannins 42.8%, flavonoids 35.5%, steroids 32.6%, alkaloids 16%, saponins 14.5% and glycosides 3.2%. The oxidative stress markers as SOD, CAT, GSH, Vit C, and Vit E were increased significantly (P < 0.05) at 50mg/kg, 100mg/kg, 150mg/kg and 200mg/kg of Husk extract of P. biglibosa treated animals and decreased significantly the MDA level as compared to control group.Treatment of animals with methanol husk extract at 50mg/kg, 100mg/kg, 150mg/kg and 200mg/kg exhibited significant hepatoprotection in rats induced with CCl4 compared to CCl4 untreated group. These results suggest that, the husk methanol extract of the plant posses therapeutic potentials in the treatment of liver disease.

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IJARIIE Shafiu Shehu Anka, Jude Nwaogu, Nura Muhammad Ahmad, and Abdulkarim Abba. "Phytochemical, Antioxidant and Hepatoprotective Activity of Parkia biglobosa Husk Methanol Extract in Albino Rats." International Journal Of Advance Research And Innovative Ideas In Education Volume 9 Issue 5 2023 Page 1494-1503
MLA Shafiu Shehu Anka, Jude Nwaogu, Nura Muhammad Ahmad, and Abdulkarim Abba. "Phytochemical, Antioxidant and Hepatoprotective Activity of Parkia biglobosa Husk Methanol Extract in Albino Rats.." International Journal Of Advance Research And Innovative Ideas In Education 9.5(2023) : 1494-1503.
APA Shafiu Shehu Anka, Jude Nwaogu, Nura Muhammad Ahmad, & Abdulkarim Abba. (2023). Phytochemical, Antioxidant and Hepatoprotective Activity of Parkia biglobosa Husk Methanol Extract in Albino Rats.. International Journal Of Advance Research And Innovative Ideas In Education, 9(5), 1494-1503.
Chicago Shafiu Shehu Anka, Jude Nwaogu, Nura Muhammad Ahmad, and Abdulkarim Abba. "Phytochemical, Antioxidant and Hepatoprotective Activity of Parkia biglobosa Husk Methanol Extract in Albino Rats.." International Journal Of Advance Research And Innovative Ideas In Education 9, no. 5 (2023) : 1494-1503.
Oxford Shafiu Shehu Anka, Jude Nwaogu, Nura Muhammad Ahmad, and Abdulkarim Abba. 'Phytochemical, Antioxidant and Hepatoprotective Activity of Parkia biglobosa Husk Methanol Extract in Albino Rats.', International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 5, 2023, p. 1494-1503. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Phytochemical__Antioxidant_and_Hepatoprotective_Activity_of_Parkia_biglobosa_Husk_Methanol_Extract_in_Albino_Rats__ijariie21646.pdf (Accessed : ).
Harvard Shafiu Shehu Anka, Jude Nwaogu, Nura Muhammad Ahmad, and Abdulkarim Abba. (2023) 'Phytochemical, Antioxidant and Hepatoprotective Activity of Parkia biglobosa Husk Methanol Extract in Albino Rats.', International Journal Of Advance Research And Innovative Ideas In Education, 9(5), pp. 1494-1503IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Phytochemical__Antioxidant_and_Hepatoprotective_Activity_of_Parkia_biglobosa_Husk_Methanol_Extract_in_Albino_Rats__ijariie21646.pdf (Accessed : )
IEEE Shafiu Shehu Anka, Jude Nwaogu, Nura Muhammad Ahmad, and Abdulkarim Abba, "Phytochemical, Antioxidant and Hepatoprotective Activity of Parkia biglobosa Husk Methanol Extract in Albino Rats.," International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 5, pp. 1494-1503, Sep-Oct 2023. [Online]. Available: https://ijariie.com/AdminUploadPdf/Phytochemical__Antioxidant_and_Hepatoprotective_Activity_of_Parkia_biglobosa_Husk_Methanol_Extract_in_Albino_Rats__ijariie21646.pdf [Accessed : ].
Turabian Shafiu Shehu Anka, Jude Nwaogu, Nura Muhammad Ahmad, and Abdulkarim Abba. "Phytochemical, Antioxidant and Hepatoprotective Activity of Parkia biglobosa Husk Methanol Extract in Albino Rats.." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 9 number 5 ().
Vancouver Shafiu Shehu Anka, Jude Nwaogu, Nura Muhammad Ahmad, and Abdulkarim Abba. Phytochemical, Antioxidant and Hepatoprotective Activity of Parkia biglobosa Husk Methanol Extract in Albino Rats.. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2023 [Cited : ]; 9(5) : 1494-1503. Available from: https://ijariie.com/AdminUploadPdf/Phytochemical__Antioxidant_and_Hepatoprotective_Activity_of_Parkia_biglobosa_Husk_Methanol_Extract_in_Albino_Rats__ijariie21646.pdf
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