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Title: :  Antiurolithiatic activity of Coffea arabica seed extract
PaperId: :  21662
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 9 Issue 5 2023
DUI:    16.0415/IJARIIE-21662
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Doniya KunjumonSrinivas college of pharmacy
Sachin Ashok PSrinivas college of pharmacy

Abstract

Pharmacology
Hyperoxaluria, Ethylene Glycol, Sodium Oxalate, Coffea Arabica
Evaluated the antiurolithiatic activity of Coffea arabica seed extract in validated experimental animal models. The antiurolithiatic activity of Coffea arabica seed extract in Ethylene Glycol and Sodium Oxalate induced animals. Preliminary phytochemical screening was carried out for Coffea arabica seed extract. The parameters like body weight, kidney weight, urine analysis, serum analysis and histopathology of kidney were studied. Ethylene Glycol and Sodium Oxalate administration resulted in hyperoxaluria as well as increased excretion of calcium, oxalate, phosphate and potassium. Treatment with Coffea arabica seed extract produced significant reduction of excretion of calcium oxalate in ethylene glycol and sodium oxalate induced animals. Treatment with Cystone 750mg/kg and Coffea arabica (low dose 100mg/kg, high dose 250mg/kg) increases the level of magnesium in ethylene glycol and sodium oxalate animals. Magnesium level which helps in prevent the formation of calcium oxalate crystals in ethylene glycol and sodium oxalate induced urolithiatic animals. Coffea arabica seed extract (low dose 100mg/kg, high dose 250mg/kg) significantly reduces the activity of calcium oxalate in the kidney indicates the reduction of stone formation. The present study concluded that Coffea arabica seed extract was found to be effective against reduction of stone formation induced by ethylene glycol and sodium oxalate.

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IJARIIE Doniya Kunjumon, and Sachin Ashok P. "Antiurolithiatic activity of Coffea arabica seed extract" International Journal Of Advance Research And Innovative Ideas In Education Volume 9 Issue 5 2023 Page 763-771
MLA Doniya Kunjumon, and Sachin Ashok P. "Antiurolithiatic activity of Coffea arabica seed extract." International Journal Of Advance Research And Innovative Ideas In Education 9.5(2023) : 763-771.
APA Doniya Kunjumon, & Sachin Ashok P. (2023). Antiurolithiatic activity of Coffea arabica seed extract. International Journal Of Advance Research And Innovative Ideas In Education, 9(5), 763-771.
Chicago Doniya Kunjumon, and Sachin Ashok P. "Antiurolithiatic activity of Coffea arabica seed extract." International Journal Of Advance Research And Innovative Ideas In Education 9, no. 5 (2023) : 763-771.
Oxford Doniya Kunjumon, and Sachin Ashok P. 'Antiurolithiatic activity of Coffea arabica seed extract', International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 5, 2023, p. 763-771. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Antiurolithiatic_activity_of_Coffea_arabica_seed_extract_ijariie21662.pdf (Accessed : 30 September 2023).
Harvard Doniya Kunjumon, and Sachin Ashok P. (2023) 'Antiurolithiatic activity of Coffea arabica seed extract', International Journal Of Advance Research And Innovative Ideas In Education, 9(5), pp. 763-771IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Antiurolithiatic_activity_of_Coffea_arabica_seed_extract_ijariie21662.pdf (Accessed : 30 September 2023)
IEEE Doniya Kunjumon, and Sachin Ashok P, "Antiurolithiatic activity of Coffea arabica seed extract," International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 5, pp. 763-771, Sep-Oct 2023. [Online]. Available: https://ijariie.com/AdminUploadPdf/Antiurolithiatic_activity_of_Coffea_arabica_seed_extract_ijariie21662.pdf [Accessed : 30 September 2023].
Turabian Doniya Kunjumon, and Sachin Ashok P. "Antiurolithiatic activity of Coffea arabica seed extract." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 9 number 5 (30 September 2023).
Vancouver Doniya Kunjumon, and Sachin Ashok P. Antiurolithiatic activity of Coffea arabica seed extract. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2023 [Cited : 30 September 2023]; 9(5) : 763-771. Available from: https://ijariie.com/AdminUploadPdf/Antiurolithiatic_activity_of_Coffea_arabica_seed_extract_ijariie21662.pdf
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