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Title: :  FORMULATION AND EVALUATION OF TOPICAL GEL OF DICLOFENAC DIETHYLAMINE
PaperId: :  22590
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 10 Issue 1 2024
DUI:    16.0415/IJARIIE-22590
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Prof. Prateek JainNRI Institute of pharmaceutical sciences Bhopal
Faizan AineeNRI Institute of pharmaceutical sciences Bhopal
Gaurav kumar NRI Institute of pharmaceutical sciences Bhopal
Gufran khanNRI Institute of pharmaceutical sciences Bhopal
Gulshan KumarNRI Institute of pharmaceutical sciences Bhopal
Gulshan DhakadNRI Institute of pharmaceutical sciences Bhopal
Hariom PariharNRI Institute of pharmaceutical sciences Bhopal
Dr. Jagdish C RathiNRI Institute of pharmaceutical sciences Bhopal

Abstract

Bechlor of pharmacy
Keywords:- Formulation1, Diclofenac diethylamine2, Topical drug delivery3, Anti-inflammatory4, and Carbopol1934
In order for the pharmacological action of a topical dermal drug product to occur, the drug must first be released from the vehicle to be available to penetrate the skin layer and reach the site of action. Drug release is mainly dependent on the characteristics of the formulation. It is phenylacetic acid derivatives developed as anti-inflammatory agent. It has analgesic anti-inflammatory antipyretic like actions like other NSAIDS. It is recommended in long term treatment of rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It is also useful acute musculoskeletal disorder post operative pain and dysmenorrhea. Diclofenac di-ethylamine gel was developed in five different formulation(F1 to F5) by employing different grades of polymers such as Carbopol 934 and Carbopol 1940.The gel was prepared and evaluated for pH, spreadability, consistency, homogeneity and viscosity. The Carbopol is high molecular weight water soluble homo polymer which posses high viscosity in low concentrations, transparency, and film forming properties these are useful for gel formation. The present study suggests that the Diclofenac di-ethylamine effectively act as invitro anti-inflammatory activity. Finally the gel formulations found to be economical and may overcome the draw backs associated with the drug during its absorption.

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IJARIIE Prof. Prateek Jain, Faizan Ainee, Gaurav kumar , Gufran khan, Gulshan Kumar, Gulshan Dhakad, Hariom Parihar, and Dr. Jagdish C Rathi. "FORMULATION AND EVALUATION OF TOPICAL GEL OF DICLOFENAC DIETHYLAMINE" International Journal Of Advance Research And Innovative Ideas In Education Volume 10 Issue 1 2024 Page 1300-1306
MLA Prof. Prateek Jain, Faizan Ainee, Gaurav kumar , Gufran khan, Gulshan Kumar, Gulshan Dhakad, Hariom Parihar, and Dr. Jagdish C Rathi. "FORMULATION AND EVALUATION OF TOPICAL GEL OF DICLOFENAC DIETHYLAMINE." International Journal Of Advance Research And Innovative Ideas In Education 10.1(2024) : 1300-1306.
APA Prof. Prateek Jain, Faizan Ainee, Gaurav kumar , Gufran khan, Gulshan Kumar, Gulshan Dhakad, Hariom Parihar, & Dr. Jagdish C Rathi. (2024). FORMULATION AND EVALUATION OF TOPICAL GEL OF DICLOFENAC DIETHYLAMINE. International Journal Of Advance Research And Innovative Ideas In Education, 10(1), 1300-1306.
Chicago Prof. Prateek Jain, Faizan Ainee, Gaurav kumar , Gufran khan, Gulshan Kumar, Gulshan Dhakad, Hariom Parihar, and Dr. Jagdish C Rathi. "FORMULATION AND EVALUATION OF TOPICAL GEL OF DICLOFENAC DIETHYLAMINE." International Journal Of Advance Research And Innovative Ideas In Education 10, no. 1 (2024) : 1300-1306.
Oxford Prof. Prateek Jain, Faizan Ainee, Gaurav kumar , Gufran khan, Gulshan Kumar, Gulshan Dhakad, Hariom Parihar, and Dr. Jagdish C Rathi. 'FORMULATION AND EVALUATION OF TOPICAL GEL OF DICLOFENAC DIETHYLAMINE', International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 1, 2024, p. 1300-1306. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/FORMULATION_AND_EVALUATION_OF_TOPICAL_GEL_OF_DICLOFENAC_DIETHYLAMINE_ijariie22590.pdf (Accessed : 04 December 2024).
Harvard Prof. Prateek Jain, Faizan Ainee, Gaurav kumar , Gufran khan, Gulshan Kumar, Gulshan Dhakad, Hariom Parihar, and Dr. Jagdish C Rathi. (2024) 'FORMULATION AND EVALUATION OF TOPICAL GEL OF DICLOFENAC DIETHYLAMINE', International Journal Of Advance Research And Innovative Ideas In Education, 10(1), pp. 1300-1306IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/FORMULATION_AND_EVALUATION_OF_TOPICAL_GEL_OF_DICLOFENAC_DIETHYLAMINE_ijariie22590.pdf (Accessed : 04 December 2024)
IEEE Prof. Prateek Jain, Faizan Ainee, Gaurav kumar , Gufran khan, Gulshan Kumar, Gulshan Dhakad, Hariom Parihar, and Dr. Jagdish C Rathi, "FORMULATION AND EVALUATION OF TOPICAL GEL OF DICLOFENAC DIETHYLAMINE," International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 1, pp. 1300-1306, Jan-Feb 2024. [Online]. Available: https://ijariie.com/AdminUploadPdf/FORMULATION_AND_EVALUATION_OF_TOPICAL_GEL_OF_DICLOFENAC_DIETHYLAMINE_ijariie22590.pdf [Accessed : 04 December 2024].
Turabian Prof. Prateek Jain, Faizan Ainee, Gaurav kumar , Gufran khan, Gulshan Kumar, Gulshan Dhakad, Hariom Parihar, and Dr. Jagdish C Rathi. "FORMULATION AND EVALUATION OF TOPICAL GEL OF DICLOFENAC DIETHYLAMINE." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 10 number 1 (04 December 2024).
Vancouver Prof. Prateek Jain, Faizan Ainee, Gaurav kumar , Gufran khan, Gulshan Kumar, Gulshan Dhakad, Hariom Parihar, and Dr. Jagdish C Rathi. FORMULATION AND EVALUATION OF TOPICAL GEL OF DICLOFENAC DIETHYLAMINE. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2024 [Cited : 04 December 2024]; 10(1) : 1300-1306. Available from: https://ijariie.com/AdminUploadPdf/FORMULATION_AND_EVALUATION_OF_TOPICAL_GEL_OF_DICLOFENAC_DIETHYLAMINE_ijariie22590.pdf
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