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Title: :  The relationship and risk factors between Ulcerative Colitis and Cholelithiasis
PaperId: :  22633
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 10 Issue 1 2024
DUI:    16.0415/IJARIIE-22633
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Shakeel AbdussalamMaster Student of Xinjiang Medical University, First Affiliated Hospital of Xinjiang Medical University
Professor Li Yali First Affiliated Hospital of Xinjiang Medical University, Xinjiang Medical University, China

Abstract

Medical
ulcerative colitis; cholelithiasis; association; risk factors
Abstract Objective: To explore the relationship and risk factors between ulcerative colitis (UC) and cholelithiasis. Methods: A total of 250 UC patients who were admitted to the First Affiliated Hospital of Xinjiang Medical University from September 2019 to October 2023 and had abdominal imaging examinations were selected . According to the inclusion and exclusion criteria, a total of 247 UC patients were included. With the help of imaging examination, the patients were divided into two groups according to the presence or absence of gallstones, including 105 patients with UC with gallstones and 142 patients with UC without gallstones. General data analysis, blood routine and inflammatory factor analysis, biochemical index analysis, clinical symptoms and comorbidity analysis, and disease characteristics analysis were conducted on the two groups of research subjects respectively; single-factor and multi-factor logistic regression analysis were conducted to explore the risk factors of patients with UC combined with cholelithiasis. Results: The majority of patients in the UC with gallstones group were 50-59 years old (39%), and the majority of patients in the UC without gallstones group were <39 years old (55%). Patients in the UC with gallstones group had a drinking history (21.0% vs 9.9%, P<0.05) was higher than that of the group without gallstones; both groups of patients had higher levels of red blood cells, monocytes, aspartate aminotransferase, alanine aminotransferase, creatinine, uric acid, cholesterol, high-density lipoprotein, and low-density lipoprotein. There was a statistically significant difference (P <0.05 ); the difference between the two groups of patients in nausea and vomiting (4.8% vs 54.4%, P <0.05) was statistically significant; the results of multivariate logistic regression analysis showed that monocytes, white blood cells and Protein, C-reactive protein, indirect bilirubin, and uric acid are independent risk factors. Conclusion: In conclusion, our study explored the link between ulcerative colitis (UC) and cholelithiasis, revealing higher prevalence of drinking history in UC patients with gallstones. Elevated blood parameters and biochemical indices suggested potential mechanisms. Multivariate analysis identified monocytes, white blood cells, C-reactive protein, and uric acid as independent risk factors. These findings emphasize the importance of considering demographic and clinical factors in UC management, warranting further research for targeted interventions.

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IJARIIE Shakeel Abdussalam, and Professor Li Yali . "The relationship and risk factors between Ulcerative Colitis and Cholelithiasis" International Journal Of Advance Research And Innovative Ideas In Education Volume 10 Issue 1 2024 Page 1456-1466
MLA Shakeel Abdussalam, and Professor Li Yali . "The relationship and risk factors between Ulcerative Colitis and Cholelithiasis." International Journal Of Advance Research And Innovative Ideas In Education 10.1(2024) : 1456-1466.
APA Shakeel Abdussalam, & Professor Li Yali . (2024). The relationship and risk factors between Ulcerative Colitis and Cholelithiasis. International Journal Of Advance Research And Innovative Ideas In Education, 10(1), 1456-1466.
Chicago Shakeel Abdussalam, and Professor Li Yali . "The relationship and risk factors between Ulcerative Colitis and Cholelithiasis." International Journal Of Advance Research And Innovative Ideas In Education 10, no. 1 (2024) : 1456-1466.
Oxford Shakeel Abdussalam, and Professor Li Yali . 'The relationship and risk factors between Ulcerative Colitis and Cholelithiasis', International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 1, 2024, p. 1456-1466. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/The_relationship_and_risk_factors_between_Ulcerative_Colitis_and_Cholelithiasis_ijariie22633.pdf (Accessed : ).
Harvard Shakeel Abdussalam, and Professor Li Yali . (2024) 'The relationship and risk factors between Ulcerative Colitis and Cholelithiasis', International Journal Of Advance Research And Innovative Ideas In Education, 10(1), pp. 1456-1466IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/The_relationship_and_risk_factors_between_Ulcerative_Colitis_and_Cholelithiasis_ijariie22633.pdf (Accessed : )
IEEE Shakeel Abdussalam, and Professor Li Yali , "The relationship and risk factors between Ulcerative Colitis and Cholelithiasis," International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 1, pp. 1456-1466, Jan-Feb 2024. [Online]. Available: https://ijariie.com/AdminUploadPdf/The_relationship_and_risk_factors_between_Ulcerative_Colitis_and_Cholelithiasis_ijariie22633.pdf [Accessed : ].
Turabian Shakeel Abdussalam, and Professor Li Yali . "The relationship and risk factors between Ulcerative Colitis and Cholelithiasis." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 10 number 1 ().
Vancouver Shakeel Abdussalam, and Professor Li Yali . The relationship and risk factors between Ulcerative Colitis and Cholelithiasis. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2024 [Cited : ]; 10(1) : 1456-1466. Available from: https://ijariie.com/AdminUploadPdf/The_relationship_and_risk_factors_between_Ulcerative_Colitis_and_Cholelithiasis_ijariie22633.pdf
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