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Title: :  FORMULATION AND EVALUATION OF MOUTH DISSOLVING ORAL FILM CONTAINING EXTRACTS OF OCIMUM SANCTUM, GLYCYRRHIZA GLABRA AND GUAVA LEAVES TO TREAT MOUTH ULCER
PaperId: :  23888
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 10 Issue 3 2024
DUI:    16.0415/IJARIIE-23888
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Vishal D. TuvarShivajirao Pawar College Of Pharmacy, Pachegaon, Ahilyanagar- 413725
Dattatray S. TuwarShivajirao Pawar College Of Pharmacy, Pachegaon, Ahilyanagar- 413725
Dr. Megha T. SalveShivajirao Pawar College Of Pharmacy, Pachegaon, Ahilyanagar- 413725

Abstract

Pharmacy
Ocimum sanctum, Glycyrrhiza glabra, Guava leaves Extracts, Oral films, Mouth ulcer, Solvent casting.
This study focused on the formulation and evaluation of mouth dissolving oral film containing extracts of ocimum sanctum, glycyrrhiza glabra and Guava leaves to treat mouth ulcer. The extracts of ocimum sanctum, glycyrrhiza glabra and Guava leaves was formulated as films by solvent casting method using various polymers viz. HPMC, Sodium alginate and Polyvinyl alcohol. Propylene glycol was used to create the films as a plasticizer, sodium starch glycolate as a super disintegrate, and honey as a sweentner. Furthermore, the films are evaluated for thickness, weight variation, folding endurance, surface pH, percentage moisture uptake, percentage moisture loss, disintegration time, in vitro drug release study and stability study. The extracts of both ocimum sanctum and glycyrrhiza glabra was collected by maceration process. The phytoconstituents study of the extract revealed the presence of alkaloids, flavonoids, tannins, steroids and saponins. The extracts were formulated into films by solvent casting method with various polymers such as HPMC, sodium alginate and polyvinyl alcohol. The idea of a quick-dissolving dose form has gained popularity as a new delivery method. By reducing dosing frequency, this approach will give better bioavailability and optimal stability. It will also avoid first pass metabolism of the medicines. From the above results it is evident that the developed formulation can be an innovative dosage form to improve the drug delivery, onset of action. Additionally, it will increase patient compliance.

Citations

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IJARIIE Vishal D. Tuvar, Dattatray S. Tuwar, and Dr. Megha T. Salve. "FORMULATION AND EVALUATION OF MOUTH DISSOLVING ORAL FILM CONTAINING EXTRACTS OF OCIMUM SANCTUM, GLYCYRRHIZA GLABRA AND GUAVA LEAVES TO TREAT MOUTH ULCER" International Journal Of Advance Research And Innovative Ideas In Education Volume 10 Issue 3 2024 Page 1774-1780
MLA Vishal D. Tuvar, Dattatray S. Tuwar, and Dr. Megha T. Salve. "FORMULATION AND EVALUATION OF MOUTH DISSOLVING ORAL FILM CONTAINING EXTRACTS OF OCIMUM SANCTUM, GLYCYRRHIZA GLABRA AND GUAVA LEAVES TO TREAT MOUTH ULCER." International Journal Of Advance Research And Innovative Ideas In Education 10.3(2024) : 1774-1780.
APA Vishal D. Tuvar, Dattatray S. Tuwar, & Dr. Megha T. Salve. (2024). FORMULATION AND EVALUATION OF MOUTH DISSOLVING ORAL FILM CONTAINING EXTRACTS OF OCIMUM SANCTUM, GLYCYRRHIZA GLABRA AND GUAVA LEAVES TO TREAT MOUTH ULCER. International Journal Of Advance Research And Innovative Ideas In Education, 10(3), 1774-1780.
Chicago Vishal D. Tuvar, Dattatray S. Tuwar, and Dr. Megha T. Salve. "FORMULATION AND EVALUATION OF MOUTH DISSOLVING ORAL FILM CONTAINING EXTRACTS OF OCIMUM SANCTUM, GLYCYRRHIZA GLABRA AND GUAVA LEAVES TO TREAT MOUTH ULCER." International Journal Of Advance Research And Innovative Ideas In Education 10, no. 3 (2024) : 1774-1780.
Oxford Vishal D. Tuvar, Dattatray S. Tuwar, and Dr. Megha T. Salve. 'FORMULATION AND EVALUATION OF MOUTH DISSOLVING ORAL FILM CONTAINING EXTRACTS OF OCIMUM SANCTUM, GLYCYRRHIZA GLABRA AND GUAVA LEAVES TO TREAT MOUTH ULCER', International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 3, 2024, p. 1774-1780. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/FORMULATION_AND_EVALUATION_OF_MOUTH_DISSOLVING_ORAL_FILM_CONTAINING_EXTRACTS_OF_OCIMUM_SANCTUM__GLYCYRRHIZA_GLABRA_AND_GUAVA_LEAVES_TO_TREAT_MOUTH_ULCER_ijariie23888.pdf (Accessed : ).
Harvard Vishal D. Tuvar, Dattatray S. Tuwar, and Dr. Megha T. Salve. (2024) 'FORMULATION AND EVALUATION OF MOUTH DISSOLVING ORAL FILM CONTAINING EXTRACTS OF OCIMUM SANCTUM, GLYCYRRHIZA GLABRA AND GUAVA LEAVES TO TREAT MOUTH ULCER', International Journal Of Advance Research And Innovative Ideas In Education, 10(3), pp. 1774-1780IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/FORMULATION_AND_EVALUATION_OF_MOUTH_DISSOLVING_ORAL_FILM_CONTAINING_EXTRACTS_OF_OCIMUM_SANCTUM__GLYCYRRHIZA_GLABRA_AND_GUAVA_LEAVES_TO_TREAT_MOUTH_ULCER_ijariie23888.pdf (Accessed : )
IEEE Vishal D. Tuvar, Dattatray S. Tuwar, and Dr. Megha T. Salve, "FORMULATION AND EVALUATION OF MOUTH DISSOLVING ORAL FILM CONTAINING EXTRACTS OF OCIMUM SANCTUM, GLYCYRRHIZA GLABRA AND GUAVA LEAVES TO TREAT MOUTH ULCER," International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 3, pp. 1774-1780, May-Jun 2024. [Online]. Available: https://ijariie.com/AdminUploadPdf/FORMULATION_AND_EVALUATION_OF_MOUTH_DISSOLVING_ORAL_FILM_CONTAINING_EXTRACTS_OF_OCIMUM_SANCTUM__GLYCYRRHIZA_GLABRA_AND_GUAVA_LEAVES_TO_TREAT_MOUTH_ULCER_ijariie23888.pdf [Accessed : ].
Turabian Vishal D. Tuvar, Dattatray S. Tuwar, and Dr. Megha T. Salve. "FORMULATION AND EVALUATION OF MOUTH DISSOLVING ORAL FILM CONTAINING EXTRACTS OF OCIMUM SANCTUM, GLYCYRRHIZA GLABRA AND GUAVA LEAVES TO TREAT MOUTH ULCER." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 10 number 3 ().
Vancouver Vishal D. Tuvar, Dattatray S. Tuwar, and Dr. Megha T. Salve. FORMULATION AND EVALUATION OF MOUTH DISSOLVING ORAL FILM CONTAINING EXTRACTS OF OCIMUM SANCTUM, GLYCYRRHIZA GLABRA AND GUAVA LEAVES TO TREAT MOUTH ULCER. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2024 [Cited : ]; 10(3) : 1774-1780. Available from: https://ijariie.com/AdminUploadPdf/FORMULATION_AND_EVALUATION_OF_MOUTH_DISSOLVING_ORAL_FILM_CONTAINING_EXTRACTS_OF_OCIMUM_SANCTUM__GLYCYRRHIZA_GLABRA_AND_GUAVA_LEAVES_TO_TREAT_MOUTH_ULCER_ijariie23888.pdf
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