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Title: :  A REVIEW ON FORMULATION AND EVALUATION OF SPIRULINA PLATENSIS CHEWABLE TABLET
PaperId: :  24247
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 10 Issue 3 2024
DUI:    16.0415/IJARIIE-24247
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Pawar Thakursing DineshLoknete Shri Dadapatil Pharate College Of Pharmacy, Mandavgan Pharata
Dr. V. M. SatputeLoknete Shri Dadapatil Pharate College Of Pharmacy, Mandavgan Pharata
Prof. S. R. GhodkeLoknete Shri Dadapatil Pharate College Of Pharmacy, Mandavgan Pharata
Dr. H. V. KambleLoknete Shri Dadapatil Pharate College Of Pharmacy, Mandavgan Pharata

Abstract

Pharmacy
Spirulina, chewable tablet, aerosil 200, PEG 6000, simplex lattice design
Among various natural food sources, spirulina contains β-carotene which is higher than other sources that is used to overcome malnutrition. However, spirulina was widely marketed in the conventional form such as capsules and tablets which are less favorable for consumption. In order to increase its acceptability, it is formulated in the chewable tablet using direct press method that meets requirements and is acceptable to the community. This study aims to determine the valid of optimal formula for spirulina chewable tablets through the development of formulas on aerosil 200 (lubricant), and PEG 6000 (glidant). This was an experimental research which was carried out by optimizing the dry extract formula of Spirulina platensis using the Simplex Lattice Design (SLD) method with Aerosil 200 as a lubricant and PEG 6000 as a glidant. The tablet's physical properties observed were organoleptic, weight uniformity, tensile strength, friability, disintegration time. The result of physical properties test were analysed using one sample t-test with a 95% confidence level. Then, the optimum formula was conduct to hedonic test. The result of the spirulina chewable tablets optimum formula was consist of 25 mg aerosil 200 (lubricant) and 5 mg PEG 6000 (glidant) with 0.58% weight uniformity deviation, 4.52 kgf/cm2 tensile strength, 0.74% friability and all the tablets meets specification for disintegration time. The validation results showed that there were no significant differences in the physical properties of the SLD prediction results with the actual results. The hedonic test showed that optimum formula still need to add mask odour to minimize the characteristic aroma and the coating material to beautify physical appearance of spirulina the chewable tablet. The optimal formula for spirulina chewable tablets and fulfilling the quality requirements of traditional medicines is using 25 mg aerosil 200 (lubricant) and 5 mg PEG 6000 (glidant)

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IJARIIE Pawar Thakursing Dinesh, Dr. V. M. Satpute, Prof. S. R. Ghodke, and Dr. H. V. Kamble. "A REVIEW ON FORMULATION AND EVALUATION OF SPIRULINA PLATENSIS CHEWABLE TABLET" International Journal Of Advance Research And Innovative Ideas In Education Volume 10 Issue 3 2024 Page 4952-4972
MLA Pawar Thakursing Dinesh, Dr. V. M. Satpute, Prof. S. R. Ghodke, and Dr. H. V. Kamble. "A REVIEW ON FORMULATION AND EVALUATION OF SPIRULINA PLATENSIS CHEWABLE TABLET." International Journal Of Advance Research And Innovative Ideas In Education 10.3(2024) : 4952-4972.
APA Pawar Thakursing Dinesh, Dr. V. M. Satpute, Prof. S. R. Ghodke, & Dr. H. V. Kamble. (2024). A REVIEW ON FORMULATION AND EVALUATION OF SPIRULINA PLATENSIS CHEWABLE TABLET. International Journal Of Advance Research And Innovative Ideas In Education, 10(3), 4952-4972.
Chicago Pawar Thakursing Dinesh, Dr. V. M. Satpute, Prof. S. R. Ghodke, and Dr. H. V. Kamble. "A REVIEW ON FORMULATION AND EVALUATION OF SPIRULINA PLATENSIS CHEWABLE TABLET." International Journal Of Advance Research And Innovative Ideas In Education 10, no. 3 (2024) : 4952-4972.
Oxford Pawar Thakursing Dinesh, Dr. V. M. Satpute, Prof. S. R. Ghodke, and Dr. H. V. Kamble. 'A REVIEW ON FORMULATION AND EVALUATION OF SPIRULINA PLATENSIS CHEWABLE TABLET', International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 3, 2024, p. 4952-4972. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/A_REVIEW_ON_FORMULATION_AND_EVALUATION_OF_SPIRULINA_PLATENSIS_CHEWABLE_TABLET_ijariie24247.pdf (Accessed : 07 March 2025).
Harvard Pawar Thakursing Dinesh, Dr. V. M. Satpute, Prof. S. R. Ghodke, and Dr. H. V. Kamble. (2024) 'A REVIEW ON FORMULATION AND EVALUATION OF SPIRULINA PLATENSIS CHEWABLE TABLET', International Journal Of Advance Research And Innovative Ideas In Education, 10(3), pp. 4952-4972IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/A_REVIEW_ON_FORMULATION_AND_EVALUATION_OF_SPIRULINA_PLATENSIS_CHEWABLE_TABLET_ijariie24247.pdf (Accessed : 07 March 2025)
IEEE Pawar Thakursing Dinesh, Dr. V. M. Satpute, Prof. S. R. Ghodke, and Dr. H. V. Kamble, "A REVIEW ON FORMULATION AND EVALUATION OF SPIRULINA PLATENSIS CHEWABLE TABLET," International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 3, pp. 4952-4972, May-Jun 2024. [Online]. Available: https://ijariie.com/AdminUploadPdf/A_REVIEW_ON_FORMULATION_AND_EVALUATION_OF_SPIRULINA_PLATENSIS_CHEWABLE_TABLET_ijariie24247.pdf [Accessed : 07 March 2025].
Turabian Pawar Thakursing Dinesh, Dr. V. M. Satpute, Prof. S. R. Ghodke, and Dr. H. V. Kamble. "A REVIEW ON FORMULATION AND EVALUATION OF SPIRULINA PLATENSIS CHEWABLE TABLET." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 10 number 3 (07 March 2025).
Vancouver Pawar Thakursing Dinesh, Dr. V. M. Satpute, Prof. S. R. Ghodke, and Dr. H. V. Kamble. A REVIEW ON FORMULATION AND EVALUATION OF SPIRULINA PLATENSIS CHEWABLE TABLET. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2024 [Cited : 07 March 2025]; 10(3) : 4952-4972. Available from: https://ijariie.com/AdminUploadPdf/A_REVIEW_ON_FORMULATION_AND_EVALUATION_OF_SPIRULINA_PLATENSIS_CHEWABLE_TABLET_ijariie24247.pdf
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