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Title: :  Angiotensin II Type 2 Receptor: A Target for Protection Against Various Disease conditions
PaperId: :  24280
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 10 Issue 3 2024
DUI:    16.0415/IJARIIE-24280
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Divya DaveSardar Patel college of Pharmacy

Abstract

Pharmacology
Angiotensin II receptors, Ang II type 2,C21,Stroke, Obesity, Metabolism, And Insulin Sensitivity, Cerebral malaria, Alzheimer’s disease
The renin-angiotensin system's protective arm contains the angiotensin AT2 receptor (AT2R), which was first identified more than 30 years ago. Since its discovery, the AT2R has grown from a binding site with unknown function to a firmly established major effector that is a target for emerging medications. In most preclinical models, the AT2R represents an endogenous protective mechanism that can be altered to treat cancer, as well as lung, renal, cardiovascular, metabolic, cutaneous, and neurological illnesses. This page offers a thorough discussion of what we now know about the AT2R, including its discovery, location within the RAS, and general functions. The properties of the AT2R, including its structure, intracellular signaling, homo- and heterodimerization, and expression, are then thoroughly examined. We describe AT2R-selective ligands, ranging from naturally occurring peptides to synthetic peptides and nonpeptide compounds utilized as research tools. We conclude by outlining the AT2R's numerous protective effects in numerous experimental disease models, its known physiological roles, and the AT2R ligands that are currently being developed for clinical use. The current review highlights the contentious issues and knowledge gaps surrounding this receptor and sheds light on potential directions for AT2R research in the future.

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IJARIIE Divya Dave. "Angiotensin II Type 2 Receptor: A Target for Protection Against Various Disease conditions" International Journal Of Advance Research And Innovative Ideas In Education Volume 10 Issue 3 2024 Page 5310-5317
MLA Divya Dave. "Angiotensin II Type 2 Receptor: A Target for Protection Against Various Disease conditions." International Journal Of Advance Research And Innovative Ideas In Education 10.3(2024) : 5310-5317.
APA Divya Dave. (2024). Angiotensin II Type 2 Receptor: A Target for Protection Against Various Disease conditions. International Journal Of Advance Research And Innovative Ideas In Education, 10(3), 5310-5317.
Chicago Divya Dave. "Angiotensin II Type 2 Receptor: A Target for Protection Against Various Disease conditions." International Journal Of Advance Research And Innovative Ideas In Education 10, no. 3 (2024) : 5310-5317.
Oxford Divya Dave. 'Angiotensin II Type 2 Receptor: A Target for Protection Against Various Disease conditions', International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 3, 2024, p. 5310-5317. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Angiotensin_II_Type_2_Receptor__A_Target_for_Protection_Against_Various_Disease_conditions_ijariie24280.pdf (Accessed : ).
Harvard Divya Dave. (2024) 'Angiotensin II Type 2 Receptor: A Target for Protection Against Various Disease conditions', International Journal Of Advance Research And Innovative Ideas In Education, 10(3), pp. 5310-5317IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Angiotensin_II_Type_2_Receptor__A_Target_for_Protection_Against_Various_Disease_conditions_ijariie24280.pdf (Accessed : )
IEEE Divya Dave, "Angiotensin II Type 2 Receptor: A Target for Protection Against Various Disease conditions," International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 3, pp. 5310-5317, May-Jun 2024. [Online]. Available: https://ijariie.com/AdminUploadPdf/Angiotensin_II_Type_2_Receptor__A_Target_for_Protection_Against_Various_Disease_conditions_ijariie24280.pdf [Accessed : ].
Turabian Divya Dave. "Angiotensin II Type 2 Receptor: A Target for Protection Against Various Disease conditions." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 10 number 3 ().
Vancouver Divya Dave. Angiotensin II Type 2 Receptor: A Target for Protection Against Various Disease conditions. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2024 [Cited : ]; 10(3) : 5310-5317. Available from: https://ijariie.com/AdminUploadPdf/Angiotensin_II_Type_2_Receptor__A_Target_for_Protection_Against_Various_Disease_conditions_ijariie24280.pdf
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