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Title: :  CHRONIC MYELOID LEUKEMIA IN CHILDREN IN MAURITANIA ABOUT 12 CASES EXPERIENCE OF THE PEDIATRIC HEMATOLOGY-ONCOLOGY DEPARTMENT AT THE NATIONAL ONCOLOGY CENTER
PaperId: :  24928
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 10 Issue 5 2024
DUI:    16.0415/IJARIIE-24928
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Ekhtelbenina ZeinCentre National of Oncology
Limam DidiCentre National of Oncology
Assiya AhmedCentre National of Oncology
Mariem CheyakhCentre National of Oncology

Abstract

Medical
Keywords: Chronic Myeloid Leukemia –Childhood–Mauritania
Introduction: Chronic myeloid leukemia is a malignant hematological disorder belonging to the group of myeloproliferative syndromes; it is rare in children. The advent of tyrosine kinase inhibitors (TKIs) has revolutionized its management. The objective of our study is to investigate the epidemiological, clinical, biological, therapeutic, and evolutionary profile of patients followed for CML. Materials and methods: This is a descriptive retrospective study spanning 12 years (2011-2023), involving children followed at the pediatric hematology-oncology department at the National Oncology Center in Nouakchott. Results: In our study, the medium age of the patients studied was 10.6 years with a sex ratio of 1. At diagnosis, 58,3% of patients were in chronic phase, % in accelerated phase, and 16,6% in blast crisis. Splenomegaly, fever, and asthenia were the most represented symptoms, and pallor was nearly constant. The medium WBC count was 153,000/mm³, platelet count 524,000/mm³. Anemia was consistently present with a medium level of 7.1 g/dl. The Philadelphia chromosome was found in 3 out of 3 tested children. Hydroxyurea was prescribed for patients in the pre-phase. Blast crisis was treated with acute leukemia protocols. Imatinib was prescribed for 10 patients with adherence difficulties. Among the 12 patients included in our study, 7 patients are alive on treatment, 3 discontinued treatment, and 2 have died.

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IJARIIE Ekhtelbenina Zein, Limam Didi, Assiya Ahmed, and Mariem Cheyakh. "CHRONIC MYELOID LEUKEMIA IN CHILDREN IN MAURITANIA ABOUT 12 CASES EXPERIENCE OF THE PEDIATRIC HEMATOLOGY-ONCOLOGY DEPARTMENT AT THE NATIONAL ONCOLOGY CENTER" International Journal Of Advance Research And Innovative Ideas In Education Volume 10 Issue 5 2024 Page 211-216
MLA Ekhtelbenina Zein, Limam Didi, Assiya Ahmed, and Mariem Cheyakh. "CHRONIC MYELOID LEUKEMIA IN CHILDREN IN MAURITANIA ABOUT 12 CASES EXPERIENCE OF THE PEDIATRIC HEMATOLOGY-ONCOLOGY DEPARTMENT AT THE NATIONAL ONCOLOGY CENTER." International Journal Of Advance Research And Innovative Ideas In Education 10.5(2024) : 211-216.
APA Ekhtelbenina Zein, Limam Didi, Assiya Ahmed, & Mariem Cheyakh. (2024). CHRONIC MYELOID LEUKEMIA IN CHILDREN IN MAURITANIA ABOUT 12 CASES EXPERIENCE OF THE PEDIATRIC HEMATOLOGY-ONCOLOGY DEPARTMENT AT THE NATIONAL ONCOLOGY CENTER. International Journal Of Advance Research And Innovative Ideas In Education, 10(5), 211-216.
Chicago Ekhtelbenina Zein, Limam Didi, Assiya Ahmed, and Mariem Cheyakh. "CHRONIC MYELOID LEUKEMIA IN CHILDREN IN MAURITANIA ABOUT 12 CASES EXPERIENCE OF THE PEDIATRIC HEMATOLOGY-ONCOLOGY DEPARTMENT AT THE NATIONAL ONCOLOGY CENTER." International Journal Of Advance Research And Innovative Ideas In Education 10, no. 5 (2024) : 211-216.
Oxford Ekhtelbenina Zein, Limam Didi, Assiya Ahmed, and Mariem Cheyakh. 'CHRONIC MYELOID LEUKEMIA IN CHILDREN IN MAURITANIA ABOUT 12 CASES EXPERIENCE OF THE PEDIATRIC HEMATOLOGY-ONCOLOGY DEPARTMENT AT THE NATIONAL ONCOLOGY CENTER', International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 5, 2024, p. 211-216. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/CHRONIC_MYELOID_LEUKEMIA_IN_CHILDREN_IN_MAURITANIA_ABOUT_12_CASES_EXPERIENCE_OF_THE_PEDIATRIC_HEMATOLOGY_ONCOLOGY_DEPARTMENT_AT_THE_NATIONAL_ONCOLOGY_CENTER_ijariie24928.pdf (Accessed : 11 December 2025).
Harvard Ekhtelbenina Zein, Limam Didi, Assiya Ahmed, and Mariem Cheyakh. (2024) 'CHRONIC MYELOID LEUKEMIA IN CHILDREN IN MAURITANIA ABOUT 12 CASES EXPERIENCE OF THE PEDIATRIC HEMATOLOGY-ONCOLOGY DEPARTMENT AT THE NATIONAL ONCOLOGY CENTER', International Journal Of Advance Research And Innovative Ideas In Education, 10(5), pp. 211-216IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/CHRONIC_MYELOID_LEUKEMIA_IN_CHILDREN_IN_MAURITANIA_ABOUT_12_CASES_EXPERIENCE_OF_THE_PEDIATRIC_HEMATOLOGY_ONCOLOGY_DEPARTMENT_AT_THE_NATIONAL_ONCOLOGY_CENTER_ijariie24928.pdf (Accessed : 11 December 2025)
IEEE Ekhtelbenina Zein, Limam Didi, Assiya Ahmed, and Mariem Cheyakh, "CHRONIC MYELOID LEUKEMIA IN CHILDREN IN MAURITANIA ABOUT 12 CASES EXPERIENCE OF THE PEDIATRIC HEMATOLOGY-ONCOLOGY DEPARTMENT AT THE NATIONAL ONCOLOGY CENTER," International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 5, pp. 211-216, Sep-Oct 2024. [Online]. Available: https://ijariie.com/AdminUploadPdf/CHRONIC_MYELOID_LEUKEMIA_IN_CHILDREN_IN_MAURITANIA_ABOUT_12_CASES_EXPERIENCE_OF_THE_PEDIATRIC_HEMATOLOGY_ONCOLOGY_DEPARTMENT_AT_THE_NATIONAL_ONCOLOGY_CENTER_ijariie24928.pdf [Accessed : 11 December 2025].
Turabian Ekhtelbenina Zein, Limam Didi, Assiya Ahmed, and Mariem Cheyakh. "CHRONIC MYELOID LEUKEMIA IN CHILDREN IN MAURITANIA ABOUT 12 CASES EXPERIENCE OF THE PEDIATRIC HEMATOLOGY-ONCOLOGY DEPARTMENT AT THE NATIONAL ONCOLOGY CENTER." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 10 number 5 (11 December 2025).
Vancouver Ekhtelbenina Zein, Limam Didi, Assiya Ahmed, and Mariem Cheyakh. CHRONIC MYELOID LEUKEMIA IN CHILDREN IN MAURITANIA ABOUT 12 CASES EXPERIENCE OF THE PEDIATRIC HEMATOLOGY-ONCOLOGY DEPARTMENT AT THE NATIONAL ONCOLOGY CENTER. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2024 [Cited : 11 December 2025]; 10(5) : 211-216. Available from: https://ijariie.com/AdminUploadPdf/CHRONIC_MYELOID_LEUKEMIA_IN_CHILDREN_IN_MAURITANIA_ABOUT_12_CASES_EXPERIENCE_OF_THE_PEDIATRIC_HEMATOLOGY_ONCOLOGY_DEPARTMENT_AT_THE_NATIONAL_ONCOLOGY_CENTER_ijariie24928.pdf
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