Call for Papers:Vol.11 Issue.3

Submission
Last date		 28-Jun-2025
Acceptance Status In One Day
Paper Publish In Two Days
Submit ManuScript

News & Updates

Submit Article

Dear Authors, Article publish in our journal for Volume-11,Issue-3. For article submission on below link: Submit Manuscript


Join As Board

Dear Reviewer, You can join our Reviewer team without given any charges in our journal. Submit Details on below link: Join As Board


Paper Publication Charges

IJARIIE APP
Download Android App

For Authors

Archives

IJARIIE Board

Downloads

Android App

Download IJARIIE APP

Authors

Title: :  Assessing the Impact of Comprehensive Chromosome Screening in Preimplantation Genetic Testing for Aneuploidy: A Meta-Analytical Review
PaperId: :  25201
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 10 Issue 5 2024
DUI:    16.0415/IJARIIE-25201
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Anindita KunduSardar Patel university, Balaghat(M.P.)India
Dr. Shubhi MishraSardar Patel university, Balaghat(M.P.)India

Abstract

Biotechnology
In Vitro Fertilization, Meta-Analysis, Preimplantation Genetic Screening
The utility of pre-implantation genetic testing (PGT-A) is controversial, with older meta-analyses demonstrating improved pregnancy outcomes, while newer trials have not shown benefit. Therefore, we performed a meta-analysis which aimed to evaluate the benefits of PGT-A using comprehensive chromosome screening (CCS) and its effects on in vitro fertilization (IVF) outcomes among randomized controlled trials (RCTs). We conducted a systematic search to identify RCTs comparing women undergoing PGT-A with CSS with women not undergoing PGT-A, from inception to December 2020. Random effects meta-analysis was utilized to calculate average odds ratios (OR) for clinical pregnancy rate (CPR), ongoing pregnancy rate (OPR), and miscarriage rate (MR). The heterogeneity of exposure was assessed using Forest plots and I2 statistics. Publication bias was evaluated using Egger’s test. Among 1251 citations, seven RCTs met the inclusion criteria. Biopsies of embryos were carried out at various developmental stages, including polar body, day 3, and day 5-6 of culture. Data was analyzed as all studies and blastocyst only. Meta-analysis failed to show improvement in OPRs using PGT-A in the all ages, <35 years old and ≥ 35 years old age groups. There was also no significant difference in CPRs in any group. The MR decreased with the use of PGT-A (among all biopsy types and among blastocyst biopsies) in the all-ages group, but not when stratifying according to patient age, <35 and ≥ 35 years old. More data regarding the risks and advantages of PGT-A are needed to make a final decision on the value of this intervention in clinical practice. The exact magnitude of the benefit of PGT-A selection cannot be correctly determined until multiple standardized protocol IVF PGT-A trials are conducted.

Citations

Copy and paste a formatted citation or use one of the links to import into a bibliography manager and reference.

IJARIIE Anindita Kundu, and Dr. Shubhi Mishra. "Assessing the Impact of Comprehensive Chromosome Screening in Preimplantation Genetic Testing for Aneuploidy: A Meta-Analytical Review" International Journal Of Advance Research And Innovative Ideas In Education Volume 10 Issue 5 2024 Page 2313-2325
MLA Anindita Kundu, and Dr. Shubhi Mishra. "Assessing the Impact of Comprehensive Chromosome Screening in Preimplantation Genetic Testing for Aneuploidy: A Meta-Analytical Review." International Journal Of Advance Research And Innovative Ideas In Education 10.5(2024) : 2313-2325.
APA Anindita Kundu, & Dr. Shubhi Mishra. (2024). Assessing the Impact of Comprehensive Chromosome Screening in Preimplantation Genetic Testing for Aneuploidy: A Meta-Analytical Review. International Journal Of Advance Research And Innovative Ideas In Education, 10(5), 2313-2325.
Chicago Anindita Kundu, and Dr. Shubhi Mishra. "Assessing the Impact of Comprehensive Chromosome Screening in Preimplantation Genetic Testing for Aneuploidy: A Meta-Analytical Review." International Journal Of Advance Research And Innovative Ideas In Education 10, no. 5 (2024) : 2313-2325.
Oxford Anindita Kundu, and Dr. Shubhi Mishra. 'Assessing the Impact of Comprehensive Chromosome Screening in Preimplantation Genetic Testing for Aneuploidy: A Meta-Analytical Review', International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 5, 2024, p. 2313-2325. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Assessing_the_Impact_of_Comprehensive_Chromosome_Screening_in_Preimplantation_Genetic_Testing_for_Aneuploidy__A_Meta_Analytical_Review_ijariie25201.pdf (Accessed : 01 November 2024).
Harvard Anindita Kundu, and Dr. Shubhi Mishra. (2024) 'Assessing the Impact of Comprehensive Chromosome Screening in Preimplantation Genetic Testing for Aneuploidy: A Meta-Analytical Review', International Journal Of Advance Research And Innovative Ideas In Education, 10(5), pp. 2313-2325IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Assessing_the_Impact_of_Comprehensive_Chromosome_Screening_in_Preimplantation_Genetic_Testing_for_Aneuploidy__A_Meta_Analytical_Review_ijariie25201.pdf (Accessed : 01 November 2024)
IEEE Anindita Kundu, and Dr. Shubhi Mishra, "Assessing the Impact of Comprehensive Chromosome Screening in Preimplantation Genetic Testing for Aneuploidy: A Meta-Analytical Review," International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 5, pp. 2313-2325, Sep-Oct 2024. [Online]. Available: https://ijariie.com/AdminUploadPdf/Assessing_the_Impact_of_Comprehensive_Chromosome_Screening_in_Preimplantation_Genetic_Testing_for_Aneuploidy__A_Meta_Analytical_Review_ijariie25201.pdf [Accessed : 01 November 2024].
Turabian Anindita Kundu, and Dr. Shubhi Mishra. "Assessing the Impact of Comprehensive Chromosome Screening in Preimplantation Genetic Testing for Aneuploidy: A Meta-Analytical Review." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 10 number 5 (01 November 2024).
Vancouver Anindita Kundu, and Dr. Shubhi Mishra. Assessing the Impact of Comprehensive Chromosome Screening in Preimplantation Genetic Testing for Aneuploidy: A Meta-Analytical Review. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2024 [Cited : 01 November 2024]; 10(5) : 2313-2325. Available from: https://ijariie.com/AdminUploadPdf/Assessing_the_Impact_of_Comprehensive_Chromosome_Screening_in_Preimplantation_Genetic_Testing_for_Aneuploidy__A_Meta_Analytical_Review_ijariie25201.pdf
BibTex EndNote RefMan RefWorks

Number Of Downloads


Last download on 11/1/2024 7:21:47 AM

Save in Google Drive

Similar-Paper

TitleArea of ResearchAuther NameAction
Evaluation of the nutritional and sensory attributes of two aromatic rices varietes from northern Madagascar "Mogodro and Madame Rose"Biological SciencesRahanitrarivony Veronirina Download
Assessing the Impact of Comprehensive Chromosome Screening in Preimplantation Genetic Testing for Aneuploidy: A Meta-Analytical ReviewBiotechnologyAnindita Kundu Download
Expansion of biosimilars in indian pharmaceutical marketBiotechnologyVadi Aryan Download
Advanced Doctorate of Philosophy Seven Months Diploma in Bio-Eco-Bio cum Bio-Eco-Bio Biotechnological Bio-Eco-Bio Plant Sciences cum Advanced & Applied Bio Plant Sciences (Bio-Eco-Bio Edible Herbal) With Second PreceedingBiogeosciences Amit Rastogi Download
Polycystic Ovary Syndrome Prediction [ML]Information Technology EngineeringChavan Ganesh Baban Download
Role of Nutrition in Chronic Kidney DiseaseFood science and NutraceuticalMs. Tanvi Sunil Ballal Download
Understanding of Valoctocogene Roxaparvovec (Roctavian) as a Breakthrough Gene Therapy for Hemophilia Type Alife Sciences Sanaullah Safi Download
Overview of artificial intelligence and NanoroboticsPharmacyKakade Swati babasaheb Download
Studies on Extraction of Flavonoids from Leaves of Artocarpus heterophyllusBiotechnologyAnsh Aggarwal Download
NANOMEDICINES IN NANOTECHNOLOGYPharmacyMohammad Shoab Shaikh Diler Download
A Study of Pseudomonas Bio Control Strains for Environmental Bio Control Inoculants ApplicationsBIOTECHNOLOGYDr. Sudhir Kumar Mishra Download
A Study of Genomics and Metabolic Reconstructions with Pseudomonas from Biotechnology BiotechnologyDr. Sudhir Kumar Mishra Download
A Study of Creation of Tailor-Made Synthetic Properties Pseudomonas Putida in Bacterial HostBIOTECHNOLOGYDr. Sudhir Kumar Mishra Download
A Study of Recent Advances in Systems Biology of Pseudomonas in BiotechnologyBiotechnologyDr. Sudhir Kumar Mishra Download
A Study of Pseudomonas Putida of Core Carbon and Energy Metabolism in BiotechnologyBIOTECHNOLOGYDr. Sudhir Kumar Mishra Download
12