Call for Papers:Vol.11 Issue.3

Submission
Last date		 28-Jun-2025
Acceptance Status In One Day
Paper Publish In Two Days
Submit ManuScript

News & Updates

Submit Article

Dear Authors, Article publish in our journal for Volume-11,Issue-3. For article submission on below link: Submit Manuscript


Join As Board

Dear Reviewer, You can join our Reviewer team without given any charges in our journal. Submit Details on below link: Join As Board


Paper Publication Charges

IJARIIE APP
Download Android App

For Authors

Archives

IJARIIE Board

Downloads

Android App

Download IJARIIE APP

Authors

Title: :  Pharmacological Evaluation of Acacetin Against Isoproterenol-Induced Cardiac Hypertrophy: A Review
PaperId: :  25312
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 10 Issue 6 2024
DUI:    16.0415/IJARIIE-25312
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Prerana S. KokeLoknete shri Dadapatil Pharate college of pharmacy, Mandavgan pharata, Pune

Abstract

Pharmaceutical Science
Acacetin, Cardiac Hypertrophy, Natural Flavonoid, Cardioprotection, Isoproterenol.
Cardiac hypertrophy, a pathological response to prolonged stress or injury, is a critical precursor to heart failure and other severe cardiovascular conditions. Experimental models using isoproterenol (ISO), a beta-adrenergic agonist, replicate many aspects of human cardiac hypertrophy, making it valuable for studying potential therapies. Acacetin, a flavonoid derived from several medicinal plants, has gained attention for its broad pharmacological actions, including antioxidant, anti-inflammatory, and anti-apoptotic effects. This review examines the therapeutic potential of acacetin in ISO-induced cardiac hypertrophy, exploring its molecular mechanisms and cardioprotective actions. Key findings from preclinical studies demonstrate that acacetin alleviates oxidative stress, reduces inflammation, and regulates calcium homeostasis, effectively mitigating cellular hypertrophy, fibrosis, and apoptosis in cardiac cells. By targeting multiple pathways—such as NF-κB, PI3K/Akt/mTOR, and MAPK—acacetin presents a comprehensive approach to preventing hypertrophy and promoting cardiac health. This review underscores the promise of acacetin as a potential therapeutic agent and highlights the need for clinical studies to confirm its efficacy and safety in cardiovascular disease management.

Citations

Copy and paste a formatted citation or use one of the links to import into a bibliography manager and reference.

IJARIIE Prerana S. Koke. "Pharmacological Evaluation of Acacetin Against Isoproterenol-Induced Cardiac Hypertrophy: A Review" International Journal Of Advance Research And Innovative Ideas In Education Volume 10 Issue 6 2024 Page 404-415
MLA Prerana S. Koke. "Pharmacological Evaluation of Acacetin Against Isoproterenol-Induced Cardiac Hypertrophy: A Review." International Journal Of Advance Research And Innovative Ideas In Education 10.6(2024) : 404-415.
APA Prerana S. Koke. (2024). Pharmacological Evaluation of Acacetin Against Isoproterenol-Induced Cardiac Hypertrophy: A Review. International Journal Of Advance Research And Innovative Ideas In Education, 10(6), 404-415.
Chicago Prerana S. Koke. "Pharmacological Evaluation of Acacetin Against Isoproterenol-Induced Cardiac Hypertrophy: A Review." International Journal Of Advance Research And Innovative Ideas In Education 10, no. 6 (2024) : 404-415.
Oxford Prerana S. Koke. 'Pharmacological Evaluation of Acacetin Against Isoproterenol-Induced Cardiac Hypertrophy: A Review', International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 6, 2024, p. 404-415. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Pharmacological_Evaluation_of_Acacetin_Against_Isoproterenol_Induced_Cardiac_Hypertrophy__A_Review_ijariie25312.pdf (Accessed : 16 November 2024).
Harvard Prerana S. Koke. (2024) 'Pharmacological Evaluation of Acacetin Against Isoproterenol-Induced Cardiac Hypertrophy: A Review', International Journal Of Advance Research And Innovative Ideas In Education, 10(6), pp. 404-415IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Pharmacological_Evaluation_of_Acacetin_Against_Isoproterenol_Induced_Cardiac_Hypertrophy__A_Review_ijariie25312.pdf (Accessed : 16 November 2024)
IEEE Prerana S. Koke, "Pharmacological Evaluation of Acacetin Against Isoproterenol-Induced Cardiac Hypertrophy: A Review," International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 6, pp. 404-415, Nov-Dec 2024. [Online]. Available: https://ijariie.com/AdminUploadPdf/Pharmacological_Evaluation_of_Acacetin_Against_Isoproterenol_Induced_Cardiac_Hypertrophy__A_Review_ijariie25312.pdf [Accessed : 16 November 2024].
Turabian Prerana S. Koke. "Pharmacological Evaluation of Acacetin Against Isoproterenol-Induced Cardiac Hypertrophy: A Review." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 10 number 6 (16 November 2024).
Vancouver Prerana S. Koke. Pharmacological Evaluation of Acacetin Against Isoproterenol-Induced Cardiac Hypertrophy: A Review. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2024 [Cited : 16 November 2024]; 10(6) : 404-415. Available from: https://ijariie.com/AdminUploadPdf/Pharmacological_Evaluation_of_Acacetin_Against_Isoproterenol_Induced_Cardiac_Hypertrophy__A_Review_ijariie25312.pdf
BibTex EndNote RefMan RefWorks

Number Of Downloads


Last download on 11/16/2024 6:25:40 AM

Save in Google Drive

Similar-Paper

TitleArea of ResearchAuther NameAction
SEEDS: ANTI-OXIDANT POWERHOUSEPharmacy DIVYA BALNE Download
The Role of Pharmacogenomics in Personalized MedicinePharmaceutical Sudipta Maitra Download
Understanding Zoonotic Diseases: Mechanisms of Transmission, Global Impact, and Strategies for Prevention and ControlPharmacyTejaswini Shivaji Khot Download
PharmacogenomicsPharmacologyMr Vijay kalyan Bhosale Download
A Review on Post Traumatic Stress DisorderPharamaceuticalDr. D. Rama Brahma Reddy Download
A REVIEW ON PHARMACEUTICAL GELSpharmaceuticsDr. R. Rama Brahma Reddy Download
REVIEW ON CERVICAL CANCERPharmaceuticsDr. D. Rama Brahma Reddy Download
FOMULATION AND EVALUATION OF METFORMIN AND VILDAGLIPTIN BILAYER TABLETSM. PHARMJeetendra kushwaha Download
REVIEW ON A FORMULATION, EVALUATION PARAMETERS OF HERBAL PARAMETERS OF HERBAL TOOTH POWDER BY USING HERBAL DRUGSPharmacyPawar Sakshi.N Download
“Bacteriophage Therapy: A Promising Solution to Combat Antibiotic Resistance”PharmacyRutuja Ashok Shelke Download
Therapeutic Potential of Bacopa monnieri in Kindling-Induced Post-Ictal Depression: A Comprehensive ReviewPharmaceutical ScienceSonali B. Kolape Download
Pharmacological Evaluation of Acacetin Against Isoproterenol-Induced Cardiac Hypertrophy: A ReviewPharmaceutical SciencePrerana S. Koke Download
Green Chemistry: Intent, Result, and PrinciplesPharmacyMr. Govinda L. Tarange Download
Covid-19 Pandemic: Viral Pathogenesis, Clinical Manifestation, Diagnostic, Evaluation and ManagementPharmacology Akshay Chaudhary Download
A SYSTEMIC REVIEW ON MEDICAL TREATMENT OF ATOPIC DERMATITIS (ECZEMA)Medical EducationMonika Devi Download
12