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Title: :  “Bacteriophage Therapy: A Promising Solution to Combat Antibiotic Resistance”
PaperId: :  25347
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 10 Issue 6 2024
DUI:    16.0415/IJARIIE-25347
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Rutuja Ashok ShelkeShivajirao pawar college of pharmacy pachegoan
Ms . Dnyaneshwar S. VyavhareShivajirao pawar college of pharmacy pachegoan
Dr. Megha T .SalveShivajirao pawar college of pharmacy pachegoan

Abstract

Pharmacy
Bacteriophages, Antibiotic resistance, Clinical trials, Pharmacological mechanisms.
Antibiotic resistance poses a major threat to global health, complicating the treatment of bacterial infections due to their prevalence, high mortality rates, and associated healthcare costs. Bacteriophages, which are viruses that target and destroy bacteria, offer a promising alternative for treating antibiotic-resistant infections. Although bacteriophage therapy was first utilized nearly a century ago, its progress was halted with the advent of antibiotics. Today, with the growing issue of antibiotic resistance, interest in bacteriophage therapy has resurfaced. Given its safety and potent antibacterial effects, certain bacteriophages, such as phiX174 and the Pyo bacteriophage complex liquid, have advanced to phase III clinical trials. In this review, we discuss the critical aspects of the antibiotic resistance crisis and the factors contributing to the renewed interest in bacteriophage applications. We summarize recent cutting-edge research and clinical data on bacteriophage therapy, covering (i) the pharmacological mechanisms and benefits of antibacterial bacteriophages, (ii) clinically relevant bacteriophage preparations and anti-bacterial treatment strategies derived from them, and (iii) bacteriophage therapeutics designed for various infection types and cancer treatments related to infections. Lastly, we address the challenges and key considerations for the future clinical development of bacteriophage therapy.

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IJARIIE Rutuja Ashok Shelke, Ms . Dnyaneshwar S. Vyavhare, and Dr. Megha T .Salve. "“Bacteriophage Therapy: A Promising Solution to Combat Antibiotic Resistance”" International Journal Of Advance Research And Innovative Ideas In Education Volume 10 Issue 6 2024 Page 688-696
MLA Rutuja Ashok Shelke, Ms . Dnyaneshwar S. Vyavhare, and Dr. Megha T .Salve. "“Bacteriophage Therapy: A Promising Solution to Combat Antibiotic Resistance”." International Journal Of Advance Research And Innovative Ideas In Education 10.6(2024) : 688-696.
APA Rutuja Ashok Shelke, Ms . Dnyaneshwar S. Vyavhare, & Dr. Megha T .Salve. (2024). “Bacteriophage Therapy: A Promising Solution to Combat Antibiotic Resistance”. International Journal Of Advance Research And Innovative Ideas In Education, 10(6), 688-696.
Chicago Rutuja Ashok Shelke, Ms . Dnyaneshwar S. Vyavhare, and Dr. Megha T .Salve. "“Bacteriophage Therapy: A Promising Solution to Combat Antibiotic Resistance”." International Journal Of Advance Research And Innovative Ideas In Education 10, no. 6 (2024) : 688-696.
Oxford Rutuja Ashok Shelke, Ms . Dnyaneshwar S. Vyavhare, and Dr. Megha T .Salve. '“Bacteriophage Therapy: A Promising Solution to Combat Antibiotic Resistance”', International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 6, 2024, p. 688-696. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/“Bacteriophage_Therapy__A_Promising_Solution_to_Combat_Antibiotic_Resistance”_ijariie25347.pdf (Accessed : 29 November 2024).
Harvard Rutuja Ashok Shelke, Ms . Dnyaneshwar S. Vyavhare, and Dr. Megha T .Salve. (2024) '“Bacteriophage Therapy: A Promising Solution to Combat Antibiotic Resistance”', International Journal Of Advance Research And Innovative Ideas In Education, 10(6), pp. 688-696IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/“Bacteriophage_Therapy__A_Promising_Solution_to_Combat_Antibiotic_Resistance”_ijariie25347.pdf (Accessed : 29 November 2024)
IEEE Rutuja Ashok Shelke, Ms . Dnyaneshwar S. Vyavhare, and Dr. Megha T .Salve, "“Bacteriophage Therapy: A Promising Solution to Combat Antibiotic Resistance”," International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 6, pp. 688-696, Nov-Dec 2024. [Online]. Available: https://ijariie.com/AdminUploadPdf/“Bacteriophage_Therapy__A_Promising_Solution_to_Combat_Antibiotic_Resistance”_ijariie25347.pdf [Accessed : 29 November 2024].
Turabian Rutuja Ashok Shelke, Ms . Dnyaneshwar S. Vyavhare, and Dr. Megha T .Salve. "“Bacteriophage Therapy: A Promising Solution to Combat Antibiotic Resistance”." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 10 number 6 (29 November 2024).
Vancouver Rutuja Ashok Shelke, Ms . Dnyaneshwar S. Vyavhare, and Dr. Megha T .Salve. “Bacteriophage Therapy: A Promising Solution to Combat Antibiotic Resistance”. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2024 [Cited : 29 November 2024]; 10(6) : 688-696. Available from: https://ijariie.com/AdminUploadPdf/“Bacteriophage_Therapy__A_Promising_Solution_to_Combat_Antibiotic_Resistance”_ijariie25347.pdf
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