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Title: :  Chronic Liver Disease: New Targets and Mechanisms
PaperId: :  25994
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 11 Issue 2 2025
DUI:    16.0415/IJARIIE-25994
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Emmanuela John SimaRayat Bahra University Mohali, Punjab
Shivani SharmaRayat Bahra University Mohali, Punjab
Diksha SharmaRayat Bahra University Mohali, Punjab
Anchal DhawanRayat Bahra University Mohali, Punjab

Abstract

Pharmacy
inflammation, fibrosis, and progressive dysfunction, Chronic liver disease (CLD)
Chronic liver disease (CLD) is a major global health concern, characterized by persistent liver inflammation, fibrosis, and progressive dysfunction. Despite advancements in understanding the pathophysiology of liver diseases, the therapeutic options remain limited. Recent research has uncovered novel molecular pathways, signaling networks, and cellular mechanisms involved in the progression of CLD, offering potential new therapeutic targets. These mechanisms include immune dysregulation, hepatic stellate cell activation, alterations in gut-liver axis, and the role of non-coding RNAs in disease progression. Additionally, emerging targets such as fibrosis biomarkers, inflammatory cytokines, and cellular senescence pathways provide exciting opportunities for early intervention and personalized treatment strategies. This review highlights the latest discoveries in chronic liver disease research, emphasizing innovative molecular targets, their therapeutic potential, and the challenges in translating these findings into clinical practice. Understanding these mechanisms could pave the way for novel treatments that effectively halt or reverse the progression of chronic liver disease, ultimately improving patient outcomes and quality of life.

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IJARIIE Emmanuela John Sima, Shivani Sharma, Diksha Sharma, and Anchal Dhawan. "Chronic Liver Disease: New Targets and Mechanisms" International Journal Of Advance Research And Innovative Ideas In Education Volume 11 Issue 2 2025 Page 656-663
MLA Emmanuela John Sima, Shivani Sharma, Diksha Sharma, and Anchal Dhawan. "Chronic Liver Disease: New Targets and Mechanisms." International Journal Of Advance Research And Innovative Ideas In Education 11.2(2025) : 656-663.
APA Emmanuela John Sima, Shivani Sharma, Diksha Sharma, & Anchal Dhawan. (2025). Chronic Liver Disease: New Targets and Mechanisms. International Journal Of Advance Research And Innovative Ideas In Education, 11(2), 656-663.
Chicago Emmanuela John Sima, Shivani Sharma, Diksha Sharma, and Anchal Dhawan. "Chronic Liver Disease: New Targets and Mechanisms." International Journal Of Advance Research And Innovative Ideas In Education 11, no. 2 (2025) : 656-663.
Oxford Emmanuela John Sima, Shivani Sharma, Diksha Sharma, and Anchal Dhawan. 'Chronic Liver Disease: New Targets and Mechanisms', International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 2, 2025, p. 656-663. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Chronic_Liver_Disease__New_Targets_and_Mechanisms_ijariie25994.pdf (Accessed : ).
Harvard Emmanuela John Sima, Shivani Sharma, Diksha Sharma, and Anchal Dhawan. (2025) 'Chronic Liver Disease: New Targets and Mechanisms', International Journal Of Advance Research And Innovative Ideas In Education, 11(2), pp. 656-663IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Chronic_Liver_Disease__New_Targets_and_Mechanisms_ijariie25994.pdf (Accessed : )
IEEE Emmanuela John Sima, Shivani Sharma, Diksha Sharma, and Anchal Dhawan, "Chronic Liver Disease: New Targets and Mechanisms," International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 2, pp. 656-663, Mar-App 2025. [Online]. Available: https://ijariie.com/AdminUploadPdf/Chronic_Liver_Disease__New_Targets_and_Mechanisms_ijariie25994.pdf [Accessed : ].
Turabian Emmanuela John Sima, Shivani Sharma, Diksha Sharma, and Anchal Dhawan. "Chronic Liver Disease: New Targets and Mechanisms." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 11 number 2 ().
Vancouver Emmanuela John Sima, Shivani Sharma, Diksha Sharma, and Anchal Dhawan. Chronic Liver Disease: New Targets and Mechanisms. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2025 [Cited : ]; 11(2) : 656-663. Available from: https://ijariie.com/AdminUploadPdf/Chronic_Liver_Disease__New_Targets_and_Mechanisms_ijariie25994.pdf
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