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Title: :  PHYTOCHEMICAL SCREENING, FORMULATION AND EVALUATION OF ANTIBACTERIAL CREAM CONTAINING EPIPHYLLUM OXYPETALUM EXTRACT
PaperId: :  26729
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 11 Issue 3 2025
DUI:    16.0415/IJARIIE-26729
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Mansi Dadasaheb KarandeRaigad college of Pharmacy, mohopre ,Raigad, Maharashtra, India
Varsha Digambar bherjeRaigad college of Pharmacy, mohopre ,Raigad, Maharashtra, India

Abstract

B-Pharmacy
Epiphyllum oxypetalum, antibacterial cream, phytochemical screening, herbal formulation, GC-MS, antimicrobial activity.
Background: Epiphyllum oxypetalum (Queen of the Night) is a night-blooming cactus known for its medicinal properties, particularly antimicrobial activity. Objective: This study aims to investigate the phytochemical constituents and antimicrobial efficacy of E. oxypetalum extract, and to formulate and evaluate an antibacterial herbal cream incorporating the extract. Methods: Phytochemical screening was performed to identify bioactive compounds such as alkaloids, flavonoids, tannins, saponins, and terpenoids. Ash value and acid-insoluble ash were determined to assess plant material quality. Advanced techniques including Thin Layer Chromatography (TLC), Paper Chromatography, and Column Chromatography were employed for phytochemical analysis, with further characterization via Gas Chromatography–Mass Spectrometry (GC-MS). An antibacterial cream was formulated using the extract and subjected to evaluations including PH, spreadability, viscosity, stability, and microbial efficacy. Antibacterial activity was assessed using the agar well diffusion method against Staphylococcus aureus and Escherichia coli. Results: GC-MS identified several antimicrobial bioactives. The formulated cream exhibited significant antibacterial activity, indicating its potential use in therapeutic skincare. Conclusion: The study supports the use of E. oxypetalum in herbal antibacterial formulations, highlighting the value of traditional medicinal plants in modern dermatological applications.

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IJARIIE Mansi Dadasaheb Karande, and Varsha Digambar bherje. "PHYTOCHEMICAL SCREENING, FORMULATION AND EVALUATION OF ANTIBACTERIAL CREAM CONTAINING EPIPHYLLUM OXYPETALUM EXTRACT" International Journal Of Advance Research And Innovative Ideas In Education Volume 11 Issue 3 2025 Page 2204-2217
MLA Mansi Dadasaheb Karande, and Varsha Digambar bherje. "PHYTOCHEMICAL SCREENING, FORMULATION AND EVALUATION OF ANTIBACTERIAL CREAM CONTAINING EPIPHYLLUM OXYPETALUM EXTRACT." International Journal Of Advance Research And Innovative Ideas In Education 11.3(2025) : 2204-2217.
APA Mansi Dadasaheb Karande, & Varsha Digambar bherje. (2025). PHYTOCHEMICAL SCREENING, FORMULATION AND EVALUATION OF ANTIBACTERIAL CREAM CONTAINING EPIPHYLLUM OXYPETALUM EXTRACT. International Journal Of Advance Research And Innovative Ideas In Education, 11(3), 2204-2217.
Chicago Mansi Dadasaheb Karande, and Varsha Digambar bherje. "PHYTOCHEMICAL SCREENING, FORMULATION AND EVALUATION OF ANTIBACTERIAL CREAM CONTAINING EPIPHYLLUM OXYPETALUM EXTRACT." International Journal Of Advance Research And Innovative Ideas In Education 11, no. 3 (2025) : 2204-2217.
Oxford Mansi Dadasaheb Karande, and Varsha Digambar bherje. 'PHYTOCHEMICAL SCREENING, FORMULATION AND EVALUATION OF ANTIBACTERIAL CREAM CONTAINING EPIPHYLLUM OXYPETALUM EXTRACT', International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 3, 2025, p. 2204-2217. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/PHYTOCHEMICAL_SCREENING__FORMULATION_AND_EVALUATION_OF_ANTIBACTERIAL_CREAM_CONTAINING_EPIPHYLLUM_OXYPETALUM_EXTRACT_ijariie26729.pdf (Accessed : ).
Harvard Mansi Dadasaheb Karande, and Varsha Digambar bherje. (2025) 'PHYTOCHEMICAL SCREENING, FORMULATION AND EVALUATION OF ANTIBACTERIAL CREAM CONTAINING EPIPHYLLUM OXYPETALUM EXTRACT', International Journal Of Advance Research And Innovative Ideas In Education, 11(3), pp. 2204-2217IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/PHYTOCHEMICAL_SCREENING__FORMULATION_AND_EVALUATION_OF_ANTIBACTERIAL_CREAM_CONTAINING_EPIPHYLLUM_OXYPETALUM_EXTRACT_ijariie26729.pdf (Accessed : )
IEEE Mansi Dadasaheb Karande, and Varsha Digambar bherje, "PHYTOCHEMICAL SCREENING, FORMULATION AND EVALUATION OF ANTIBACTERIAL CREAM CONTAINING EPIPHYLLUM OXYPETALUM EXTRACT," International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 3, pp. 2204-2217, May-Jun 2025. [Online]. Available: https://ijariie.com/AdminUploadPdf/PHYTOCHEMICAL_SCREENING__FORMULATION_AND_EVALUATION_OF_ANTIBACTERIAL_CREAM_CONTAINING_EPIPHYLLUM_OXYPETALUM_EXTRACT_ijariie26729.pdf [Accessed : ].
Turabian Mansi Dadasaheb Karande, and Varsha Digambar bherje. "PHYTOCHEMICAL SCREENING, FORMULATION AND EVALUATION OF ANTIBACTERIAL CREAM CONTAINING EPIPHYLLUM OXYPETALUM EXTRACT." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 11 number 3 ().
Vancouver Mansi Dadasaheb Karande, and Varsha Digambar bherje. PHYTOCHEMICAL SCREENING, FORMULATION AND EVALUATION OF ANTIBACTERIAL CREAM CONTAINING EPIPHYLLUM OXYPETALUM EXTRACT. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2025 [Cited : ]; 11(3) : 2204-2217. Available from: https://ijariie.com/AdminUploadPdf/PHYTOCHEMICAL_SCREENING__FORMULATION_AND_EVALUATION_OF_ANTIBACTERIAL_CREAM_CONTAINING_EPIPHYLLUM_OXYPETALUM_EXTRACT_ijariie26729.pdf
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