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Title: :  ANTIHYPERLIPIDEMIC ACTIVITITY OF MEDICINAL PLANT IN HIGH FAT DIET INDUCED HYPERLIPEMIA IN EXPERIMENTAL ANIMAL
PaperId: :  26746
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 11 Issue 3 2025
DUI:    16.0415/IJARIIE-26746
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Bhakti NagareVIDYABHARATI COLLEGE OF PHARMACY,SANT GADGE BABA AMRAVATI UNIVERSITY ,AMRAVATI
Anjali M. WankhadeVIDYABHARATI COLLEGE OF PHARMACY,SANT GADGE BABA AMRAVATI UNIVERSITY ,AMRAVATI
Vivek V. PaithankarVIDYABHARATI COLLEGE OF PHARMACY,SANT GADGE BABA AMRAVATI UNIVERSITY ,AMRAVATI

Abstract

M.pharm in Pharmacology
Hyperlipidemia; Flemingia Strobilifera, HFD, Atrovastatin.
Objective: The present study is an attempt to investigate its anti-hyperlipidemic activity of ethanolic extract of Flemingia Strobilifera (EEFS) using high-fat diet (HFDs) induced hyperlipidemia. Methods: EEFS was evaluated for anti-hyperlipidemic activity in HFD induced hyperlipidemic rats. A comparison was also made between the action of Flemingia Strobilifera extract and a known anti-hyperlipidemic drug atorvastatin (10 mg/kg body weight). The results of the study were expressed as mean ± standard error, and data were analyzed using two-way analysis of variance test followed by tukkey’s test for multiple comparisons. Values of p<0.0001 were considered as significant significant anti-hyperlipidemic activity and hence it could be a potential herbal medicine as an adjuvant with existing therapy for the treatment of hyperlipidemia. Results: Oral administration of 200, 400 mg/kg body weight of the EEFS exhibited a significant reduction (p<0.01) in serum lipid parameters such as total cholesterol, triglycerides, low-density lipoprotein (LDL), very LDL, and increase in high-density lipoprotein (HDL)in hyperlipidemic rats of both models as compared to hyperlipidemic control statistically. These extracts were found to possess better anti-hyperlipidemic potential. Conclusion: Our results demonstrated that MESA bark possessed significant antihyperlipdemic activity.

Citations

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IJARIIE Bhakti Nagare, Anjali M. Wankhade, and Vivek V. Paithankar. "ANTIHYPERLIPIDEMIC ACTIVITITY OF MEDICINAL PLANT IN HIGH FAT DIET INDUCED HYPERLIPEMIA IN EXPERIMENTAL ANIMAL" International Journal Of Advance Research And Innovative Ideas In Education Volume 11 Issue 3 2025 Page 2518-2534
MLA Bhakti Nagare, Anjali M. Wankhade, and Vivek V. Paithankar. "ANTIHYPERLIPIDEMIC ACTIVITITY OF MEDICINAL PLANT IN HIGH FAT DIET INDUCED HYPERLIPEMIA IN EXPERIMENTAL ANIMAL." International Journal Of Advance Research And Innovative Ideas In Education 11.3(2025) : 2518-2534.
APA Bhakti Nagare, Anjali M. Wankhade, & Vivek V. Paithankar. (2025). ANTIHYPERLIPIDEMIC ACTIVITITY OF MEDICINAL PLANT IN HIGH FAT DIET INDUCED HYPERLIPEMIA IN EXPERIMENTAL ANIMAL. International Journal Of Advance Research And Innovative Ideas In Education, 11(3), 2518-2534.
Chicago Bhakti Nagare, Anjali M. Wankhade, and Vivek V. Paithankar. "ANTIHYPERLIPIDEMIC ACTIVITITY OF MEDICINAL PLANT IN HIGH FAT DIET INDUCED HYPERLIPEMIA IN EXPERIMENTAL ANIMAL." International Journal Of Advance Research And Innovative Ideas In Education 11, no. 3 (2025) : 2518-2534.
Oxford Bhakti Nagare, Anjali M. Wankhade, and Vivek V. Paithankar. 'ANTIHYPERLIPIDEMIC ACTIVITITY OF MEDICINAL PLANT IN HIGH FAT DIET INDUCED HYPERLIPEMIA IN EXPERIMENTAL ANIMAL', International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 3, 2025, p. 2518-2534. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/ANTIHYPERLIPIDEMIC___ACTIVITITY_OF_MEDICINAL_PLANT_IN_HIGH_FAT_DIET_INDUCED_HYPERLIPEMIA_IN_EXPERIMENTAL_ANIMAL_ijariie26746.pdf (Accessed : 26 December 2025).
Harvard Bhakti Nagare, Anjali M. Wankhade, and Vivek V. Paithankar. (2025) 'ANTIHYPERLIPIDEMIC ACTIVITITY OF MEDICINAL PLANT IN HIGH FAT DIET INDUCED HYPERLIPEMIA IN EXPERIMENTAL ANIMAL', International Journal Of Advance Research And Innovative Ideas In Education, 11(3), pp. 2518-2534IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/ANTIHYPERLIPIDEMIC___ACTIVITITY_OF_MEDICINAL_PLANT_IN_HIGH_FAT_DIET_INDUCED_HYPERLIPEMIA_IN_EXPERIMENTAL_ANIMAL_ijariie26746.pdf (Accessed : 26 December 2025)
IEEE Bhakti Nagare, Anjali M. Wankhade, and Vivek V. Paithankar, "ANTIHYPERLIPIDEMIC ACTIVITITY OF MEDICINAL PLANT IN HIGH FAT DIET INDUCED HYPERLIPEMIA IN EXPERIMENTAL ANIMAL," International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 3, pp. 2518-2534, May-Jun 2025. [Online]. Available: https://ijariie.com/AdminUploadPdf/ANTIHYPERLIPIDEMIC___ACTIVITITY_OF_MEDICINAL_PLANT_IN_HIGH_FAT_DIET_INDUCED_HYPERLIPEMIA_IN_EXPERIMENTAL_ANIMAL_ijariie26746.pdf [Accessed : 26 December 2025].
Turabian Bhakti Nagare, Anjali M. Wankhade, and Vivek V. Paithankar. "ANTIHYPERLIPIDEMIC ACTIVITITY OF MEDICINAL PLANT IN HIGH FAT DIET INDUCED HYPERLIPEMIA IN EXPERIMENTAL ANIMAL." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 11 number 3 (26 December 2025).
Vancouver Bhakti Nagare, Anjali M. Wankhade, and Vivek V. Paithankar. ANTIHYPERLIPIDEMIC ACTIVITITY OF MEDICINAL PLANT IN HIGH FAT DIET INDUCED HYPERLIPEMIA IN EXPERIMENTAL ANIMAL. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2025 [Cited : 26 December 2025]; 11(3) : 2518-2534. Available from: https://ijariie.com/AdminUploadPdf/ANTIHYPERLIPIDEMIC___ACTIVITITY_OF_MEDICINAL_PLANT_IN_HIGH_FAT_DIET_INDUCED_HYPERLIPEMIA_IN_EXPERIMENTAL_ANIMAL_ijariie26746.pdf
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