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Title: :  RASAYANA FORMULATIONS IN RASA SHASTRA: ANCIENT CONCEPTS AND MODERN EVIDENCE
PaperId: :  27526
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 11 Issue 5 2025
DUI:    16.0415/IJARIIE-27526
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Dr. AnupamaDesh Bhagat Ayurvedic College & Hospital, Punjab, India
Dr. Rajni BhardwajDesh Bhagat Ayurvedic College & Hospital, Punjab, India

Abstract

Ayurveda
Rasayana; Rasa Shastra; Bhasma; Swarna Bhasma; Abhraka Bhasma; Rasasindura; Gandhaka Rasayana; Makardhwaja; Ayurveda; nanomedicine
Background: Rasayana, one of Ayurveda’s core disciplines, aims to promote longevity, disease resistance, and healthy ageing. Rasa Shastra expands this pharmacopeia with potent herbo-mineral Rasayana formulations such as Swarna Bhasma, Abhraka Bhasma, Gandhaka Rasayana, Makardhwaja, and Rasasindura. Objective: To synthesize classical Ayurvedic concepts of Rasayana with contemporary analytical, preclinical, and clinical evidence, highlighting safety, mechanisms, and gaps. Methods: Narrative study of contemporary literature and classical treatises indexed in PubMed, ScienceDirect, and DOAJ, with an emphasis on toxicity, analytical characterization, and human investigations on the main Rasa-Rasayana. Results: Modern studies report that (i) Swarna Bhasma largely comprises elemental gold with crystalline nanoscale features; (ii) Abhraka Bhasma demonstrates distinct mineralogical profiles with emerging data on genotoxicity endpoints; (iii) Rasasindura is predominantly α-HgS with low solubility and distinct physicochemical signatures; (iv) Makardhwaja shows acceptable sub-chronic safety in rodent models at therapeutic multiples; and (v) Gandhaka Rasayana has early clinical signals in specific indications, with pediatric protocols underway. Conclusions: Classical Rasayana goals align with modern findings on immunomodulation, antioxidant effects, and improved bioavailability via nano-/sub-micron structuring. Stronger standardized trials and harmonized safety frameworks are needed to translate Rasayana into evidence-based integrative care.

Citations

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IJARIIE Dr. Anupama, and Dr. Rajni Bhardwaj. "RASAYANA FORMULATIONS IN RASA SHASTRA: ANCIENT CONCEPTS AND MODERN EVIDENCE" International Journal Of Advance Research And Innovative Ideas In Education Volume 11 Issue 5 2025 Page 473-476
MLA Dr. Anupama, and Dr. Rajni Bhardwaj. "RASAYANA FORMULATIONS IN RASA SHASTRA: ANCIENT CONCEPTS AND MODERN EVIDENCE." International Journal Of Advance Research And Innovative Ideas In Education 11.5(2025) : 473-476.
APA Dr. Anupama, & Dr. Rajni Bhardwaj. (2025). RASAYANA FORMULATIONS IN RASA SHASTRA: ANCIENT CONCEPTS AND MODERN EVIDENCE. International Journal Of Advance Research And Innovative Ideas In Education, 11(5), 473-476.
Chicago Dr. Anupama, and Dr. Rajni Bhardwaj. "RASAYANA FORMULATIONS IN RASA SHASTRA: ANCIENT CONCEPTS AND MODERN EVIDENCE." International Journal Of Advance Research And Innovative Ideas In Education 11, no. 5 (2025) : 473-476.
Oxford Dr. Anupama, and Dr. Rajni Bhardwaj. 'RASAYANA FORMULATIONS IN RASA SHASTRA: ANCIENT CONCEPTS AND MODERN EVIDENCE', International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 5, 2025, p. 473-476. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/RASAYANA_FORMULATIONS_IN_RASA_SHASTRA__ANCIENT_CONCEPTS_AND_MODERN_EVIDENCE_ijariie27526.pdf (Accessed : 06 October 2025).
Harvard Dr. Anupama, and Dr. Rajni Bhardwaj. (2025) 'RASAYANA FORMULATIONS IN RASA SHASTRA: ANCIENT CONCEPTS AND MODERN EVIDENCE', International Journal Of Advance Research And Innovative Ideas In Education, 11(5), pp. 473-476IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/RASAYANA_FORMULATIONS_IN_RASA_SHASTRA__ANCIENT_CONCEPTS_AND_MODERN_EVIDENCE_ijariie27526.pdf (Accessed : 06 October 2025)
IEEE Dr. Anupama, and Dr. Rajni Bhardwaj, "RASAYANA FORMULATIONS IN RASA SHASTRA: ANCIENT CONCEPTS AND MODERN EVIDENCE," International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 5, pp. 473-476, Sep-Oct 2025. [Online]. Available: https://ijariie.com/AdminUploadPdf/RASAYANA_FORMULATIONS_IN_RASA_SHASTRA__ANCIENT_CONCEPTS_AND_MODERN_EVIDENCE_ijariie27526.pdf [Accessed : 06 October 2025].
Turabian Dr. Anupama, and Dr. Rajni Bhardwaj. "RASAYANA FORMULATIONS IN RASA SHASTRA: ANCIENT CONCEPTS AND MODERN EVIDENCE." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 11 number 5 (06 October 2025).
Vancouver Dr. Anupama, and Dr. Rajni Bhardwaj. RASAYANA FORMULATIONS IN RASA SHASTRA: ANCIENT CONCEPTS AND MODERN EVIDENCE. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2025 [Cited : 06 October 2025]; 11(5) : 473-476. Available from: https://ijariie.com/AdminUploadPdf/RASAYANA_FORMULATIONS_IN_RASA_SHASTRA__ANCIENT_CONCEPTS_AND_MODERN_EVIDENCE_ijariie27526.pdf
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