Call for Papers:Vol.12 Issue.2

Submission
Last date		 28-Apr-2026
Acceptance Status In One Day
Paper Publish In Two Days
Submit ManuScript

News & Updates

Submit Article

Dear Authors, Article publish in our journal for Volume-12,Issue-2. For article submission on below link: Submit Manuscript


Join As Board

Dear Reviewer, You can join our Reviewer team without given any charges in our journal. Submit Details on below link: Join As Board


Paper Publication Charges

IJARIIE APP
Download Android App

For Authors

Archives

IJARIIE Board

Downloads

Android App

Download IJARIIE APP

Authors

Title: :  Carfilzomib: A Promising Proteasome Inhibitor For the Treatment of Cervical Cancer
PaperId: :  28005
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 12 Issue 1 2026
DUI:    16.0415/IJARIIE-28005
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Shashi Kumar Yadav(Department of Gynecology) The Fifth Affiliated Hospital of Xinjiang Medical University
Professor Jinling Yi (Department of Gynecology) The Fifth Affiliated Hospital of Xinjiang Medical University

Abstract

Medical (Gynecology)
Carfilzomib, Cervical Cancer, Proteasome Inhibitor, Conventional Chemotherapy, Multiple Myeloma.
Cervical cancer is still a major health problem around the world. It is the fourth most common cancer in women. Even though screening and vaccination have gotten better, there are still not many good treatments for advanced and recurrent cervical cancer. Platinum-based chemotherapy works only a little and causes a lot of resistance to build up. Proteasome inhibitors are a new type of drug that has changed the way we treat blood cancers, especially multiple myeloma. Carfilzomib, a second-generation irreversible proteasome inhibitor, has exhibited encouraging preclinical efficacy across multiple solid tumors. This thorough review brings together the latest research on carfilzomib and other proteasome inhibitors that could be used to treat cervical cancer. It looks at how these drugs work at the molecular level, how well they work in preclinical studies, how they could be used in combination with other drugs, how they might become resistant, and what this means for real-world use. Although direct clinical evidence for carfilzomib in cervical cancer is scarce, preclinical studies involving related proteasome inhibitors exhibit substantial anti-tumor activity via various mechanisms, including the induction of apoptosis, cell cycle arrest, and increased sensitivity to conventional chemotherapy. The ubiquitin-proteasome system has been confirmed as a viable therapeutic target in cervical cancer, with combination strategies demonstrating significant potential for addressing drug resistance and enhancing therapeutic efficacy.

Citations

Copy and paste a formatted citation or use one of the links to import into a bibliography manager and reference.

IJARIIE Shashi Kumar Yadav, and Professor Jinling Yi . "Carfilzomib: A Promising Proteasome Inhibitor For the Treatment of Cervical Cancer" International Journal Of Advance Research And Innovative Ideas In Education Volume 12 Issue 1 2026 Page 601-613
MLA Shashi Kumar Yadav, and Professor Jinling Yi . "Carfilzomib: A Promising Proteasome Inhibitor For the Treatment of Cervical Cancer." International Journal Of Advance Research And Innovative Ideas In Education 12.1(2026) : 601-613.
APA Shashi Kumar Yadav, & Professor Jinling Yi . (2026). Carfilzomib: A Promising Proteasome Inhibitor For the Treatment of Cervical Cancer. International Journal Of Advance Research And Innovative Ideas In Education, 12(1), 601-613.
Chicago Shashi Kumar Yadav, and Professor Jinling Yi . "Carfilzomib: A Promising Proteasome Inhibitor For the Treatment of Cervical Cancer." International Journal Of Advance Research And Innovative Ideas In Education 12, no. 1 (2026) : 601-613.
Oxford Shashi Kumar Yadav, and Professor Jinling Yi . 'Carfilzomib: A Promising Proteasome Inhibitor For the Treatment of Cervical Cancer', International Journal Of Advance Research And Innovative Ideas In Education, vol. 12, no. 1, 2026, p. 601-613. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Carfilzomib__A_Promising_Proteasome_Inhibitor_For_the_Treatment_of_Cervical_Cancer_ijariie28005.pdf (Accessed : 19 March 2026).
Harvard Shashi Kumar Yadav, and Professor Jinling Yi . (2026) 'Carfilzomib: A Promising Proteasome Inhibitor For the Treatment of Cervical Cancer', International Journal Of Advance Research And Innovative Ideas In Education, 12(1), pp. 601-613IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Carfilzomib__A_Promising_Proteasome_Inhibitor_For_the_Treatment_of_Cervical_Cancer_ijariie28005.pdf (Accessed : 19 March 2026)
IEEE Shashi Kumar Yadav, and Professor Jinling Yi , "Carfilzomib: A Promising Proteasome Inhibitor For the Treatment of Cervical Cancer," International Journal Of Advance Research And Innovative Ideas In Education, vol. 12, no. 1, pp. 601-613, Jan-Feb 2026. [Online]. Available: https://ijariie.com/AdminUploadPdf/Carfilzomib__A_Promising_Proteasome_Inhibitor_For_the_Treatment_of_Cervical_Cancer_ijariie28005.pdf [Accessed : 19 March 2026].
Turabian Shashi Kumar Yadav, and Professor Jinling Yi . "Carfilzomib: A Promising Proteasome Inhibitor For the Treatment of Cervical Cancer." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 12 number 1 (19 March 2026).
Vancouver Shashi Kumar Yadav, and Professor Jinling Yi . Carfilzomib: A Promising Proteasome Inhibitor For the Treatment of Cervical Cancer. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2026 [Cited : 19 March 2026]; 12(1) : 601-613. Available from: https://ijariie.com/AdminUploadPdf/Carfilzomib__A_Promising_Proteasome_Inhibitor_For_the_Treatment_of_Cervical_Cancer_ijariie28005.pdf
BibTex EndNote RefMan RefWorks

Number Of Downloads


Last download on 3/19/2026 12:52:57 PM

Save in Google Drive

Similar-Paper

TitleArea of ResearchAuther NameAction
Liver Disease in Pregnancy: A Comprehensive Clinical AnalysisMedical (Gynecology)Roshan Shah Download
Carfilzomib: A Promising Proteasome Inhibitor For the Treatment of Cervical CancerMedical (Gynecology)Shashi Kumar Yadav Download
Human Papillomavirus (HPV) vaccination among young adultsMedical Dr. Isma Bibi Download
Epidemiological, Clinical, and Therapeutic Aspects of Spontaneous Abortions at Cheikh Zayed Hospital (Nouakchott)obstetric and gyneacologyYahya Tfeil Download
MATERNAL-FETAL PROGNOSIS OF PREECLAMPSIA IN PRIMIPAROUS WOMEN: A REPORT OF 53 CASES AT CHEIKH ZAYED HOSPITALobstetric and gyneacologyYahya Tfeil Download
Intraparietal Migration of copper Intrauterine Device: Case Report and Literature ReviewBiological & Medical SciencesKhadijetou VILALY Download
Caesarean Sections: Experience of a Tertiary Hospital in a sub-Saharan CountryBiological & Medical SciencesMohamed Salem Lehbib Download
A CASE REPORT ON HYDROSALPINX IN A WOMAN WITH A PARTIAL HYSTERECTOMYHealth careNagunuri Shruthi Download
Vaginal Discharge in females.A ReviewPharmaceutical scienceAnjali Bhagwan Wankhede Download
A Study on Awareness of Birth Preparedness and Safe Delivery in Selected Rural Area in BangladeshGynecology related medical specialtiesMaksuda Khatun Download
CONCEPTUAL STUDY OF AYURVEDIC MANAGEMENT OF LEUCORRHEAAyurvedaDr. Hari Krishna Shriwas Download
THE EFFICACY OF LAJA BADAR ELA HIMA IN EMESIS GRAVIDARUMMedical scienceDr. Amit Shinde Download