Call for Papers:Vol.12 Issue.2

Submission
Last date		 28-Apr-2026
Acceptance Status In One Day
Paper Publish In Two Days
Submit ManuScript

News & Updates

Submit Article

Dear Authors, Article publish in our journal for Volume-12,Issue-2. For article submission on below link: Submit Manuscript


Join As Board

Dear Reviewer, You can join our Reviewer team without given any charges in our journal. Submit Details on below link: Join As Board


Paper Publication Charges

IJARIIE APP
Download Android App

For Authors

Archives

IJARIIE Board

Downloads

Android App

Download IJARIIE APP

Authors

Title: :  Atherosclerotic Cardiovascular Disease Among Patients with Type 2 Diabetes: A Comparison Based on Peripheral Blood Inflammatory Marker Levels (SIL, PLR, NLR). A systematic review of reported incidence.
PaperId: :  28034
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 12 Issue 1 2026
DUI:    16.0415/IJARIIE-28034
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Mohamed Omar Mohamed AliThe First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Wang NingThe First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.

Abstract

Medical (Internal Medicine Endocrinology )
World Health Organization (WHO), Atherosclerotic cardiovascular disease (ASCVD) , Type 2 Diabetes Mellitus (T2DM).
Background: Atherosclerotic cardiovascular disease (ASCVD) is a major cause of morbidity and mortality among individuals with Type 2 Diabetes Mellitus (T2DM). Chronic inflammation plays a crucial role in the development of both T2DM and cardiovascular diseases. Inflammatory markers such as Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and the Systemic Immune-Inflammation Index (SII) have been suggested as potential biomarkers for cardiovascular risk in diabetic patients. This systematic review aims to assess the incidence of ASCVD and the relationship between NLR, PLR, and SII levels and ASCVD in T2DM patients. Methods: A systematic review of studies published between 2010 and 2024 was conducted by searching PubMed, Embase, and Cochrane Library databases. Studies were included if they examined the association between NLR, PLR, or SII or ASCVD outcomes in T2DM patients, such as ischemic heart disease (SIHD), diabetic retinopathy (DR), or coronary artery disease (CAD). The quality of the studies was assessed using the Newcastle-Ottawa Scale (NOS), and relevant data such as study design, sample size, participant demographics, and statistical methods were extracted. The findings from eligible studies were summarized using a narrative synthesis. Results: A total of 12 studies were included in the review. The review found that the burden of ASCVD among T2DM patients is significantly high ranging between 16% to 46%. The review found that higher levels of NLR were significantly associated with an increased risk of ASCVD in T2DM patients. Similarly, elevated PLR and SII were also linked to a higher risk of ASCVD. Conclusion: The burden of ASCVD among T2DM patients is high. Elevated levels of NLR, PLR, and SII are consistently associated with an increased risk of ASCVD in T2DM patients. These inflammatory markers can serve as useful tools for predicting cardiovascular complications and identifying high-risk diabetic patients early. However, the variability in study designs and populations indicates the need for further large-scale, long-term studies to confirm these findings and explore their clinical relevance in everyday practice.

Citations

Copy and paste a formatted citation or use one of the links to import into a bibliography manager and reference.

IJARIIE Mohamed Omar Mohamed Ali, and Wang Ning. "Atherosclerotic Cardiovascular Disease Among Patients with Type 2 Diabetes: A Comparison Based on Peripheral Blood Inflammatory Marker Levels (SIL, PLR, NLR). A systematic review of reported incidence." International Journal Of Advance Research And Innovative Ideas In Education Volume 12 Issue 1 2026 Page 782-792
MLA Mohamed Omar Mohamed Ali, and Wang Ning. "Atherosclerotic Cardiovascular Disease Among Patients with Type 2 Diabetes: A Comparison Based on Peripheral Blood Inflammatory Marker Levels (SIL, PLR, NLR). A systematic review of reported incidence.." International Journal Of Advance Research And Innovative Ideas In Education 12.1(2026) : 782-792.
APA Mohamed Omar Mohamed Ali, & Wang Ning. (2026). Atherosclerotic Cardiovascular Disease Among Patients with Type 2 Diabetes: A Comparison Based on Peripheral Blood Inflammatory Marker Levels (SIL, PLR, NLR). A systematic review of reported incidence.. International Journal Of Advance Research And Innovative Ideas In Education, 12(1), 782-792.
Chicago Mohamed Omar Mohamed Ali, and Wang Ning. "Atherosclerotic Cardiovascular Disease Among Patients with Type 2 Diabetes: A Comparison Based on Peripheral Blood Inflammatory Marker Levels (SIL, PLR, NLR). A systematic review of reported incidence.." International Journal Of Advance Research And Innovative Ideas In Education 12, no. 1 (2026) : 782-792.
Oxford Mohamed Omar Mohamed Ali, and Wang Ning. 'Atherosclerotic Cardiovascular Disease Among Patients with Type 2 Diabetes: A Comparison Based on Peripheral Blood Inflammatory Marker Levels (SIL, PLR, NLR). A systematic review of reported incidence.', International Journal Of Advance Research And Innovative Ideas In Education, vol. 12, no. 1, 2026, p. 782-792. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Atherosclerotic_Cardiovascular_Disease_Among_Patients_with_Type_2_Diabetes__A_Comparison_Based_on_Peripheral_Blood_Inflammatory_Marker_Levels__SIL__PLR__NLR___A_systematic_review_of_reported_incidence__ijariie28034.pdf (Accessed : ).
Harvard Mohamed Omar Mohamed Ali, and Wang Ning. (2026) 'Atherosclerotic Cardiovascular Disease Among Patients with Type 2 Diabetes: A Comparison Based on Peripheral Blood Inflammatory Marker Levels (SIL, PLR, NLR). A systematic review of reported incidence.', International Journal Of Advance Research And Innovative Ideas In Education, 12(1), pp. 782-792IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Atherosclerotic_Cardiovascular_Disease_Among_Patients_with_Type_2_Diabetes__A_Comparison_Based_on_Peripheral_Blood_Inflammatory_Marker_Levels__SIL__PLR__NLR___A_systematic_review_of_reported_incidence__ijariie28034.pdf (Accessed : )
IEEE Mohamed Omar Mohamed Ali, and Wang Ning, "Atherosclerotic Cardiovascular Disease Among Patients with Type 2 Diabetes: A Comparison Based on Peripheral Blood Inflammatory Marker Levels (SIL, PLR, NLR). A systematic review of reported incidence.," International Journal Of Advance Research And Innovative Ideas In Education, vol. 12, no. 1, pp. 782-792, Jan-Feb 2026. [Online]. Available: https://ijariie.com/AdminUploadPdf/Atherosclerotic_Cardiovascular_Disease_Among_Patients_with_Type_2_Diabetes__A_Comparison_Based_on_Peripheral_Blood_Inflammatory_Marker_Levels__SIL__PLR__NLR___A_systematic_review_of_reported_incidence__ijariie28034.pdf [Accessed : ].
Turabian Mohamed Omar Mohamed Ali, and Wang Ning. "Atherosclerotic Cardiovascular Disease Among Patients with Type 2 Diabetes: A Comparison Based on Peripheral Blood Inflammatory Marker Levels (SIL, PLR, NLR). A systematic review of reported incidence.." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 12 number 1 ().
Vancouver Mohamed Omar Mohamed Ali, and Wang Ning. Atherosclerotic Cardiovascular Disease Among Patients with Type 2 Diabetes: A Comparison Based on Peripheral Blood Inflammatory Marker Levels (SIL, PLR, NLR). A systematic review of reported incidence.. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2026 [Cited : ]; 12(1) : 782-792. Available from: https://ijariie.com/AdminUploadPdf/Atherosclerotic_Cardiovascular_Disease_Among_Patients_with_Type_2_Diabetes__A_Comparison_Based_on_Peripheral_Blood_Inflammatory_Marker_Levels__SIL__PLR__NLR___A_systematic_review_of_reported_incidence__ijariie28034.pdf
BibTex EndNote RefMan RefWorks

Number Of Downloads



Save in Google Drive

Similar-Paper

TitleArea of ResearchAuther NameAction
Atherosclerotic Cardiovascular Disease Among Patients with Type 2 Diabetes: A Comparison Based on Peripheral Blood Inflammatory Marker Levels (SIL, PLR, NLR). A systematic review of reported incidence.Medical (Internal Medicine Endocrinology )Mohamed Omar Mohamed Ali Download
MANAGEMENT OF GRAHANI ROGA W.S.R. TO I.B.S. IN AYURVEDA - A CASE STUDYAyurveda Dr. ABHISHEK VIJAYKUMAR LANJEWAR Download