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Title: :  Development and Characterization of Empagliflozin Oro Dispersible Film by Solvent Casting Method
PaperId: :  25625
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 11 Issue 1 2025
DUI:    16.0415/IJARIIE-25625
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Sunil Tandulkar Dr. Vedprakash Patil Pharmacy College, Chh. Sambhajinagar
Syed Shoaib AliDr. Vedprakash Patil Pharmacy College, Chh. Sambhajinagar

Abstract

Master of Pharmacy
Empagliflozin, Oro-dispersible films, Solvent Casting Method, Compatibility, Antidiabetic
e objective of this study was to develop an oro dispersible film (ODF) of the antidiabetic drug Empagliflozin, using a solvent casting method and incorporating key excipients such as polymers, plasticizers, sweeteners, and a saliva-stimulating agent. As Empagliflozin is a BCS Class III drug, its solubility was enhanced by preparing an inclusion complex with β-Cyclodextrin via physical blending. The optimized formulation (F8) demonstrated excellent mouth feel, mechanical strength, and rapid disintegration (20 seconds), with 90.5% of the drug released within 3 minutes. These films were characterized for parameters such as thickness, weight uniformity, drug content, dissolution rate, and mechanical properties, with stability studies showing promising results for shelf-life stability. The development of Empagliflozin ODFs presents a significant advancement in diabetes management, of ering an ef ective, convenient, and patient-friendly dosage form that improves medication adherence and therapeutic outcomes.

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IJARIIE Sunil Tandulkar , and Syed Shoaib Ali. "Development and Characterization of Empagliflozin Oro Dispersible Film by Solvent Casting Method" International Journal Of Advance Research And Innovative Ideas In Education Volume 11 Issue 1 2025 Page 250-262
MLA Sunil Tandulkar , and Syed Shoaib Ali. "Development and Characterization of Empagliflozin Oro Dispersible Film by Solvent Casting Method." International Journal Of Advance Research And Innovative Ideas In Education 11.1(2025) : 250-262.
APA Sunil Tandulkar , & Syed Shoaib Ali. (2025). Development and Characterization of Empagliflozin Oro Dispersible Film by Solvent Casting Method. International Journal Of Advance Research And Innovative Ideas In Education, 11(1), 250-262.
Chicago Sunil Tandulkar , and Syed Shoaib Ali. "Development and Characterization of Empagliflozin Oro Dispersible Film by Solvent Casting Method." International Journal Of Advance Research And Innovative Ideas In Education 11, no. 1 (2025) : 250-262.
Oxford Sunil Tandulkar , and Syed Shoaib Ali. 'Development and Characterization of Empagliflozin Oro Dispersible Film by Solvent Casting Method', International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 1, 2025, p. 250-262. Available from IJARIIE, http://ijariie.com/AdminUploadPdf/Development_and_Characterization_of_Empagliflozin_Oro_Dispersible_Film_by_Solvent_Casting_Method_ijariie25625.pdf (Accessed : ).
Harvard Sunil Tandulkar , and Syed Shoaib Ali. (2025) 'Development and Characterization of Empagliflozin Oro Dispersible Film by Solvent Casting Method', International Journal Of Advance Research And Innovative Ideas In Education, 11(1), pp. 250-262IJARIIE [Online]. Available at: http://ijariie.com/AdminUploadPdf/Development_and_Characterization_of_Empagliflozin_Oro_Dispersible_Film_by_Solvent_Casting_Method_ijariie25625.pdf (Accessed : )
IEEE Sunil Tandulkar , and Syed Shoaib Ali, "Development and Characterization of Empagliflozin Oro Dispersible Film by Solvent Casting Method," International Journal Of Advance Research And Innovative Ideas In Education, vol. 11, no. 1, pp. 250-262, Jan-Feb 2025. [Online]. Available: http://ijariie.com/AdminUploadPdf/Development_and_Characterization_of_Empagliflozin_Oro_Dispersible_Film_by_Solvent_Casting_Method_ijariie25625.pdf [Accessed : ].
Turabian Sunil Tandulkar , and Syed Shoaib Ali. "Development and Characterization of Empagliflozin Oro Dispersible Film by Solvent Casting Method." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 11 number 1 ().
Vancouver Sunil Tandulkar , and Syed Shoaib Ali. Development and Characterization of Empagliflozin Oro Dispersible Film by Solvent Casting Method. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2025 [Cited : ]; 11(1) : 250-262. Available from: http://ijariie.com/AdminUploadPdf/Development_and_Characterization_of_Empagliflozin_Oro_Dispersible_Film_by_Solvent_Casting_Method_ijariie25625.pdf
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