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Title: :  Effectiveness of alpha lipoic acid on oral squamous cell carcinoma
PaperId: :  14824
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 7 Issue 4 2021
DUI:    16.0415/IJARIIE-14824
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Harini GSaveetha Institute Of Medical and Technical Sciences.
Dr.GopinathSaveetha Institute Of Medical and Technical Sciences.

Abstract

DENTISTRY
: alpha – stages-antioxidants-OSF
Oral submucous fibrosis (OSF) is a chronic irreversible condition of the oral mucosa with proven malignant potential. However, till date, there has been a dearth of effective management strategies. This study used alpha lipoic acid, an antioxidant, in oral form to determine if it could be useful in managing OSF patients. A case-control study was conducted on 18 patients of OSF (9 cases and 9 controls). The case group was treated using alpha lipoic acid in addition to the intralesional steroid and hyaluronidase injections used in the control group. The cases in the alpha lipoic acid group exhibited better relief of symptoms such as burning sensation of the mucosa and mouth opening, as compared to the controls. The use of alpha lipoic acid along with intralesional steroids and hyaluronidase caused reversal of higher clinical stages to lower ones. The use of an antioxidant, alpha lipoic acid, along with conventional therapy of intralesional steroid injections definitely seems to have a beneficial impact in the management of OSF.

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IJARIIE Harini G, and Dr.Gopinath. "Effectiveness of alpha lipoic acid on oral squamous cell carcinoma" International Journal Of Advance Research And Innovative Ideas In Education Volume 7 Issue 4 2021 Page 4-12
MLA Harini G, and Dr.Gopinath. "Effectiveness of alpha lipoic acid on oral squamous cell carcinoma." International Journal Of Advance Research And Innovative Ideas In Education 7.4(2021) : 4-12.
APA Harini G, & Dr.Gopinath. (2021). Effectiveness of alpha lipoic acid on oral squamous cell carcinoma. International Journal Of Advance Research And Innovative Ideas In Education, 7(4), 4-12.
Chicago Harini G, and Dr.Gopinath. "Effectiveness of alpha lipoic acid on oral squamous cell carcinoma." International Journal Of Advance Research And Innovative Ideas In Education 7, no. 4 (2021) : 4-12.
Oxford Harini G, and Dr.Gopinath. 'Effectiveness of alpha lipoic acid on oral squamous cell carcinoma', International Journal Of Advance Research And Innovative Ideas In Education, vol. 7, no. 4, 2021, p. 4-12. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Effectiveness_of_alpha_lipoic_acid_on_oral_squamous_cell_carcinoma_ijariie14824.pdf (Accessed : 12 February 2025).
Harvard Harini G, and Dr.Gopinath. (2021) 'Effectiveness of alpha lipoic acid on oral squamous cell carcinoma', International Journal Of Advance Research And Innovative Ideas In Education, 7(4), pp. 4-12IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Effectiveness_of_alpha_lipoic_acid_on_oral_squamous_cell_carcinoma_ijariie14824.pdf (Accessed : 12 February 2025)
IEEE Harini G, and Dr.Gopinath, "Effectiveness of alpha lipoic acid on oral squamous cell carcinoma," International Journal Of Advance Research And Innovative Ideas In Education, vol. 7, no. 4, pp. 4-12, Jul-Aug 2021. [Online]. Available: https://ijariie.com/AdminUploadPdf/Effectiveness_of_alpha_lipoic_acid_on_oral_squamous_cell_carcinoma_ijariie14824.pdf [Accessed : 12 February 2025].
Turabian Harini G, and Dr.Gopinath. "Effectiveness of alpha lipoic acid on oral squamous cell carcinoma." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 7 number 4 (12 February 2025).
Vancouver Harini G, and Dr.Gopinath. Effectiveness of alpha lipoic acid on oral squamous cell carcinoma. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2021 [Cited : 12 February 2025]; 7(4) : 4-12. Available from: https://ijariie.com/AdminUploadPdf/Effectiveness_of_alpha_lipoic_acid_on_oral_squamous_cell_carcinoma_ijariie14824.pdf
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