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Title: :  STIMULATION OF CEPHALOSPORIN PRODUCTION DURING THE FERMENTATION OF CEPHALOSPORIUM ACREMONIUM IMMOBILIZED IN PVA-ALGINATE BEADS BY ULTRASONICATION
PaperId: :  15466
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 7 Issue 5 2021
DUI:    16.0415/IJARIIE-15466
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Dr. A. SWAROOPA RANIDepartment of Bio-Technology, JNTUA-OTPRI, Anantapuramu, Andhra Pradesh-515001, India
DR.A.KIRAN KUMARDepartment of Chemistry, University College of Technology, Osmania University-500007, Telangana, India

Abstract

BIOTECHNOLOGY
Cephalosporin, immobilization, ultrasonication, C. acremonium
Production of antibiotics is one of the most important areas in the field of applied microbiology and cephalosporin is one of the best-used antibiotics till today. Conventional methods of fermentation for more productivity are by immobilization and bioreactor studies. During recent years a drive towards “process intensification” is leading to the search for diverse fields like sound, microwave, photoenergy etc to provide unusual environment for the enhanced product formation. In this view, a study has been undertaken to see the effect of sonication on the cephalosporin formation by C. acremonium ATCC 48272 immobilized in PVA-Alginate beads compared with that of control. Sonication at 10 KHz for 10 min; 280C showed that sonication of fermented medium at every 24 hrs is effective, which gave a yield of 418.23 g/ml and almost remained stable for 8 days without much decline in yield of the product; when compared to control & if sonication was stopped at 24 hrs, drop in the yield was noticed. Sonication during growth stage plays a negative role because early stages of growth cells are sensitive to sonication, but at production stage higher yield was noticed due to cavitation effect. Ultrasonication improved both external & internal mass transfer. Enhancement in cephalosporin production is discussed in detail.

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IJARIIE Dr. A. SWAROOPA RANI, and DR.A.KIRAN KUMAR. "STIMULATION OF CEPHALOSPORIN PRODUCTION DURING THE FERMENTATION OF CEPHALOSPORIUM ACREMONIUM IMMOBILIZED IN PVA-ALGINATE BEADS BY ULTRASONICATION" International Journal Of Advance Research And Innovative Ideas In Education Volume 7 Issue 5 2021 Page 1176-1180
MLA Dr. A. SWAROOPA RANI, and DR.A.KIRAN KUMAR. "STIMULATION OF CEPHALOSPORIN PRODUCTION DURING THE FERMENTATION OF CEPHALOSPORIUM ACREMONIUM IMMOBILIZED IN PVA-ALGINATE BEADS BY ULTRASONICATION." International Journal Of Advance Research And Innovative Ideas In Education 7.5(2021) : 1176-1180.
APA Dr. A. SWAROOPA RANI, & DR.A.KIRAN KUMAR. (2021). STIMULATION OF CEPHALOSPORIN PRODUCTION DURING THE FERMENTATION OF CEPHALOSPORIUM ACREMONIUM IMMOBILIZED IN PVA-ALGINATE BEADS BY ULTRASONICATION. International Journal Of Advance Research And Innovative Ideas In Education, 7(5), 1176-1180.
Chicago Dr. A. SWAROOPA RANI, and DR.A.KIRAN KUMAR. "STIMULATION OF CEPHALOSPORIN PRODUCTION DURING THE FERMENTATION OF CEPHALOSPORIUM ACREMONIUM IMMOBILIZED IN PVA-ALGINATE BEADS BY ULTRASONICATION." International Journal Of Advance Research And Innovative Ideas In Education 7, no. 5 (2021) : 1176-1180.
Oxford Dr. A. SWAROOPA RANI, and DR.A.KIRAN KUMAR. 'STIMULATION OF CEPHALOSPORIN PRODUCTION DURING THE FERMENTATION OF CEPHALOSPORIUM ACREMONIUM IMMOBILIZED IN PVA-ALGINATE BEADS BY ULTRASONICATION', International Journal Of Advance Research And Innovative Ideas In Education, vol. 7, no. 5, 2021, p. 1176-1180. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/STIMULATION_OF_CEPHALOSPORIN_PRODUCTION_DURING_THE_FERMENTATION_OF_CEPHALOSPORIUM_ACREMONIUM_IMMOBILIZED_IN__PVA_ALGINATE_BEADS_BY_ULTRASONICATION_ijariie15466.pdf (Accessed : ).
Harvard Dr. A. SWAROOPA RANI, and DR.A.KIRAN KUMAR. (2021) 'STIMULATION OF CEPHALOSPORIN PRODUCTION DURING THE FERMENTATION OF CEPHALOSPORIUM ACREMONIUM IMMOBILIZED IN PVA-ALGINATE BEADS BY ULTRASONICATION', International Journal Of Advance Research And Innovative Ideas In Education, 7(5), pp. 1176-1180IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/STIMULATION_OF_CEPHALOSPORIN_PRODUCTION_DURING_THE_FERMENTATION_OF_CEPHALOSPORIUM_ACREMONIUM_IMMOBILIZED_IN__PVA_ALGINATE_BEADS_BY_ULTRASONICATION_ijariie15466.pdf (Accessed : )
IEEE Dr. A. SWAROOPA RANI, and DR.A.KIRAN KUMAR, "STIMULATION OF CEPHALOSPORIN PRODUCTION DURING THE FERMENTATION OF CEPHALOSPORIUM ACREMONIUM IMMOBILIZED IN PVA-ALGINATE BEADS BY ULTRASONICATION," International Journal Of Advance Research And Innovative Ideas In Education, vol. 7, no. 5, pp. 1176-1180, Sep-Oct 2021. [Online]. Available: https://ijariie.com/AdminUploadPdf/STIMULATION_OF_CEPHALOSPORIN_PRODUCTION_DURING_THE_FERMENTATION_OF_CEPHALOSPORIUM_ACREMONIUM_IMMOBILIZED_IN__PVA_ALGINATE_BEADS_BY_ULTRASONICATION_ijariie15466.pdf [Accessed : ].
Turabian Dr. A. SWAROOPA RANI, and DR.A.KIRAN KUMAR. "STIMULATION OF CEPHALOSPORIN PRODUCTION DURING THE FERMENTATION OF CEPHALOSPORIUM ACREMONIUM IMMOBILIZED IN PVA-ALGINATE BEADS BY ULTRASONICATION." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 7 number 5 ().
Vancouver Dr. A. SWAROOPA RANI, and DR.A.KIRAN KUMAR. STIMULATION OF CEPHALOSPORIN PRODUCTION DURING THE FERMENTATION OF CEPHALOSPORIUM ACREMONIUM IMMOBILIZED IN PVA-ALGINATE BEADS BY ULTRASONICATION. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2021 [Cited : ]; 7(5) : 1176-1180. Available from: https://ijariie.com/AdminUploadPdf/STIMULATION_OF_CEPHALOSPORIN_PRODUCTION_DURING_THE_FERMENTATION_OF_CEPHALOSPORIUM_ACREMONIUM_IMMOBILIZED_IN__PVA_ALGINATE_BEADS_BY_ULTRASONICATION_ijariie15466.pdf
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