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Title: :  Formulation and evaluation of omeprazole pellets by using fluidized bed processor
PaperId: :  23543
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 10 Issue 2 2024
DUI:    16.0415/IJARIIE-23543
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Bhadane Sarang S.Loknete Dr. J D Pawar College of Pharmacy, Manur, Kalwan, Nashik

Abstract

Pharmaceutical Science
fluidized Bed Processor, Enteric, Pellets, HPMC.
The current study aims to develop and analyze delayed release Omeprazole pellets using a fluidized bed processor. Using an enteric film coating method, different drug loading, barrier coating, and enteric coating compositions were used to create the different formulations of Omeprazole delayed release pellets. Two types of polymers were employed in the formulation: HPMC K30 and HPMC E5. These polymers were utilized in the production of a capsule designed to have a long-lasting effect by attaching to the intestinal mucosa and relieving an active duodenal ulcer. Omeprazole is an enzyme H+/K+ ATPase inhibitor that is selective and non-competitive. Enteric coated dosage forms are developed to shield the substance from the effects of stomach acid and to stabilize it in low pH circumstances when administered orally. In the formulation of batches, there are variations in the polymer concentration. Therefore, the two elements are addressed in factorial design 22. FTIR spectroscopy was utilized to investigate the interaction between the excipients and omeprazole. To study the release rate retarded effect, four suggested formulations (F1–F4) were prepared using different amounts of polymers. The weight fluctuation, particle size determination, flow characteristics, and drug content of the pellets were then assessed. Pharmacopeial criteria were met by every formulation. All batches are created by the procedure for drug stacking by employing a fluidized bed processor.

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IJARIIE Bhadane Sarang S.. "Formulation and evaluation of omeprazole pellets by using fluidized bed processor" International Journal Of Advance Research And Innovative Ideas In Education Volume 10 Issue 2 2024 Page 5110-5123
MLA Bhadane Sarang S.. "Formulation and evaluation of omeprazole pellets by using fluidized bed processor." International Journal Of Advance Research And Innovative Ideas In Education 10.2(2024) : 5110-5123.
APA Bhadane Sarang S.. (2024). Formulation and evaluation of omeprazole pellets by using fluidized bed processor. International Journal Of Advance Research And Innovative Ideas In Education, 10(2), 5110-5123.
Chicago Bhadane Sarang S.. "Formulation and evaluation of omeprazole pellets by using fluidized bed processor." International Journal Of Advance Research And Innovative Ideas In Education 10, no. 2 (2024) : 5110-5123.
Oxford Bhadane Sarang S.. 'Formulation and evaluation of omeprazole pellets by using fluidized bed processor', International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 2, 2024, p. 5110-5123. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Formulation_and_evaluation_of_omeprazole_pellets_by_using_fluidized_bed_processor_ijariie23543.pdf (Accessed : ).
Harvard Bhadane Sarang S.. (2024) 'Formulation and evaluation of omeprazole pellets by using fluidized bed processor', International Journal Of Advance Research And Innovative Ideas In Education, 10(2), pp. 5110-5123IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Formulation_and_evaluation_of_omeprazole_pellets_by_using_fluidized_bed_processor_ijariie23543.pdf (Accessed : )
IEEE Bhadane Sarang S., "Formulation and evaluation of omeprazole pellets by using fluidized bed processor," International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 2, pp. 5110-5123, Mar-App 2024. [Online]. Available: https://ijariie.com/AdminUploadPdf/Formulation_and_evaluation_of_omeprazole_pellets_by_using_fluidized_bed_processor_ijariie23543.pdf [Accessed : ].
Turabian Bhadane Sarang S.. "Formulation and evaluation of omeprazole pellets by using fluidized bed processor." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 10 number 2 ().
Vancouver Bhadane Sarang S.. Formulation and evaluation of omeprazole pellets by using fluidized bed processor. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2024 [Cited : ]; 10(2) : 5110-5123. Available from: https://ijariie.com/AdminUploadPdf/Formulation_and_evaluation_of_omeprazole_pellets_by_using_fluidized_bed_processor_ijariie23543.pdf
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