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Title: :  Analysis Of Mangosteen Peel Ethanol Extract (Garcinia Mangostana L.) Against The Effectiveness Of Anti-Dyslipidemia In Male Rats Fed A High-Fat Diet
PaperId: :  19516
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 9 Issue 2 2023
DUI:    16.0415/IJARIIE-19516
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
Luo YongMaster of Clinical Medicine Study Program, Faculty of Medicine, Dentistry and Health Sciences, Universitas Prima Indonesia

Abstract

Clinical Medicine
mangosteen peel, dyslipidemia, ethanol, fat
Data in Indonesia (Riskesdas) in 2013 showed that there were 35.9% of the Indonesian population aged ≥ 15 years with abnormal cholesterol levels of a very high proportion of LDL (≥ 190 mg/dl), 22.9 % had HDL levels that were less than 40 mg/dl, and 11.9% with very high triglyceride levels (≥ 500 mg/dl). Mangosteen peel contains an organic compound, namely xanthones, known as anti-inflammatories and antioxidants that are strong and thought to be analgesics. Therefore, researchers are interested in exploring the effectiveness of anti-dyslipidemia from mangosteen peel extract. This study was experimental with a pre-and Post-test group-only control design approach using male Wistar rats as animals. This research was conducted in April 2022 at the Medanese Herbarium FMIPA USU, the Pharmacognosy Laboratory of the USU Faculty of Pharmacy, and the USU Pharmaceutical Pharmacology Laboratory. Mangosteen peel ethanol extract results contain several phytochemical compounds, including Alkaloids, Saponins, Flavonoids, Tannins, Steroids, and Terpenoids. Ethanol extract from mangosteen fruit peel significantly decreased total Cholesterol (P-value < 0.05), lowered triglyceride levels (P-value = 0.029), fell LDL levels (P-value < 0.05), and dropped SGOT levels (Value = 0.029) and SGPT (P-value < 0.05) compared to the control group. Mangosteen peel ethanol extract can also significantly increase HDL levels (P-value = 0.029)

Citations

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IJARIIE Luo Yong. "Analysis Of Mangosteen Peel Ethanol Extract (Garcinia Mangostana L.) Against The Effectiveness Of Anti-Dyslipidemia In Male Rats Fed A High-Fat Diet" International Journal Of Advance Research And Innovative Ideas In Education Volume 9 Issue 2 2023 Page 1077-1082
MLA Luo Yong. "Analysis Of Mangosteen Peel Ethanol Extract (Garcinia Mangostana L.) Against The Effectiveness Of Anti-Dyslipidemia In Male Rats Fed A High-Fat Diet." International Journal Of Advance Research And Innovative Ideas In Education 9.2(2023) : 1077-1082.
APA Luo Yong. (2023). Analysis Of Mangosteen Peel Ethanol Extract (Garcinia Mangostana L.) Against The Effectiveness Of Anti-Dyslipidemia In Male Rats Fed A High-Fat Diet. International Journal Of Advance Research And Innovative Ideas In Education, 9(2), 1077-1082.
Chicago Luo Yong. "Analysis Of Mangosteen Peel Ethanol Extract (Garcinia Mangostana L.) Against The Effectiveness Of Anti-Dyslipidemia In Male Rats Fed A High-Fat Diet." International Journal Of Advance Research And Innovative Ideas In Education 9, no. 2 (2023) : 1077-1082.
Oxford Luo Yong. 'Analysis Of Mangosteen Peel Ethanol Extract (Garcinia Mangostana L.) Against The Effectiveness Of Anti-Dyslipidemia In Male Rats Fed A High-Fat Diet', International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 2, 2023, p. 1077-1082. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/Analysis_Of_Mangosteen_Peel_Ethanol_Extract__Garcinia_Mangostana_L___Against_The_Effectiveness_Of_Anti_Dyslipidemia_In_Male_Rats_Fed_A_High_Fat_Diet_ijariie19516.pdf (Accessed : ).
Harvard Luo Yong. (2023) 'Analysis Of Mangosteen Peel Ethanol Extract (Garcinia Mangostana L.) Against The Effectiveness Of Anti-Dyslipidemia In Male Rats Fed A High-Fat Diet', International Journal Of Advance Research And Innovative Ideas In Education, 9(2), pp. 1077-1082IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/Analysis_Of_Mangosteen_Peel_Ethanol_Extract__Garcinia_Mangostana_L___Against_The_Effectiveness_Of_Anti_Dyslipidemia_In_Male_Rats_Fed_A_High_Fat_Diet_ijariie19516.pdf (Accessed : )
IEEE Luo Yong, "Analysis Of Mangosteen Peel Ethanol Extract (Garcinia Mangostana L.) Against The Effectiveness Of Anti-Dyslipidemia In Male Rats Fed A High-Fat Diet," International Journal Of Advance Research And Innovative Ideas In Education, vol. 9, no. 2, pp. 1077-1082, Mar-App 2023. [Online]. Available: https://ijariie.com/AdminUploadPdf/Analysis_Of_Mangosteen_Peel_Ethanol_Extract__Garcinia_Mangostana_L___Against_The_Effectiveness_Of_Anti_Dyslipidemia_In_Male_Rats_Fed_A_High_Fat_Diet_ijariie19516.pdf [Accessed : ].
Turabian Luo Yong. "Analysis Of Mangosteen Peel Ethanol Extract (Garcinia Mangostana L.) Against The Effectiveness Of Anti-Dyslipidemia In Male Rats Fed A High-Fat Diet." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 9 number 2 ().
Vancouver Luo Yong. Analysis Of Mangosteen Peel Ethanol Extract (Garcinia Mangostana L.) Against The Effectiveness Of Anti-Dyslipidemia In Male Rats Fed A High-Fat Diet. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2023 [Cited : ]; 9(2) : 1077-1082. Available from: https://ijariie.com/AdminUploadPdf/Analysis_Of_Mangosteen_Peel_Ethanol_Extract__Garcinia_Mangostana_L___Against_The_Effectiveness_Of_Anti_Dyslipidemia_In_Male_Rats_Fed_A_High_Fat_Diet_ijariie19516.pdf
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