Logo
  • Home
  • About Us
    • Aim and Scope
    • Research Area
    • Impact Factor
    • Indexing
  • For Authors
    • Authors Guidelines
    • How to publish paper?
    • Download Paper format
    • Submit Manuscript
    • Processing Charges
    • Download Copyrights Form
    • Submit Payment-Copyrights
  • Archives
    • Current Issues
    • Past Issues
    • Conference Issues
    • Special Issues
    • Advance Search
  • IJARIIE Board
    • Join as IJARIIE Board
    • Advisory Board
    • Editorial Board
    • Sr. Reviewer Board
    • Jr. Reviewer Board
  • Proposal
    • Conferece Proposal
    • Special Proposal
    • Faqs
  • Contact Us
  • Payment Detail

Call for Papers:Vol.11 Issue.3

Submission
Last date
28-Jun-2025
Acceptance Status In One Day
Paper Publish In Two Days
Submit ManuScript

News & Updates

Submit Article

Dear Authors, Article publish in our journal for Volume-11,Issue-3. For article submission on below link: Submit Manuscript


Join As Board

Dear Reviewer, You can join our Reviewer team without given any charges in our journal. Submit Details on below link: Join As Board


Paper Publication Charges

IJARIIE APP
Download Android App

For Authors

  • How to Publish Paper
  • Submit Manuscript
  • Processing Charges
  • Submit Payment

Archives

  • Current Issue
  • Past Issue

IJARIIE Board

  • Member Of Board
  • Join As Board

Downloads

  • Authors Guidelines
  • Manuscript Template
  • Copyrights Form

Android App

Download IJARIIE APP
  • Authors
  • Abstract
  • Citations
  • Downloads
  • Similar-Paper

Authors

Title: :  STABILITY INDICATNG HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF AMBROXOL HCL AND LORATADINE
PaperId: :  22527
Published in:   International Journal Of Advance Research And Innovative Ideas In Education
Publisher:   IJARIIE
e-ISSN:   2395-4396
Volume/Issue:    Volume 10 Issue 1 2024
DUI:    16.0415/IJARIIE-22527
Licence: :   IJARIIE is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author NameAuthor Institute
N Ranjith kumarVenkateshwara institute of Pharmaceutical Sciences, Cherlapally, Nalgonda
D.BhuvaneshwariVenkateshwara institute of Pharmaceutical Sciences, Cherlapally, Nalgonda
K.PramodVenkateshwara institute of Pharmaceutical Sciences, Cherlapally, Nalgonda
M.Rajavardhan reddyVenkateshwara institute of Pharmaceutical Sciences, Cherlapally, Nalgonda

Abstract

pharmacy
Ambroxol Hydrochloride, Loratadine, Area under Curve, UV-Spectroscopy, Stability indicating.
The objective of present work was to develop a simple, accurate, rapid and precise Stability Indicating UV- Spectrophotometric method for simultaneous estimation of Ambroxol hydrochloride (AMB) and Loratadine (LORA) in bulk and tablet Pharmaceutical dosage form using Area Under Curve (AUC) method. It involves measurement of area under curve in the range of 310-320 nm for AMB and 240-250 nm for LORA in methanol. The linearity was observed in the concentration range of 12-72µg/ml for AMB and 1-6µg/ml for LORA with a correlation coefficient (r2) of 0.999 for AMB and 0.998 for LORA respectively. Assay results of marketed formulation were found to be 98.85% for AMB and 100.11% for LORA. Satisfactory values of percent recovery indicated accuracy of the method. The value of % RSD for Intra-day and Inter-day precision were found to be 1.1718 and 0.2018 for AMB and 0.6159 and 1.3696 for LORA respectively. Limit of Detection and Quantitation was found to be 0.2207µg/ml and 0.6688µg/ml for AMB and 0.6648µg/ml and 1.6548µg/ml for LORA respectively. The proposed method was successfully applied for quantitative detection of AMB and LORA in pharmaceutical dosage form. The method was validated according to ICH guidelines.

Citations

Copy and paste a formatted citation or use one of the links to import into a bibliography manager and reference.

IJARIIE N Ranjith kumar, D.Bhuvaneshwari, K.Pramod, and M.Rajavardhan reddy. "STABILITY INDICATNG HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF AMBROXOL HCL AND LORATADINE" International Journal Of Advance Research And Innovative Ideas In Education Volume 10 Issue 1 2024 Page 903-921
MLA N Ranjith kumar, D.Bhuvaneshwari, K.Pramod, and M.Rajavardhan reddy. "STABILITY INDICATNG HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF AMBROXOL HCL AND LORATADINE." International Journal Of Advance Research And Innovative Ideas In Education 10.1(2024) : 903-921.
APA N Ranjith kumar, D.Bhuvaneshwari, K.Pramod, & M.Rajavardhan reddy. (2024). STABILITY INDICATNG HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF AMBROXOL HCL AND LORATADINE. International Journal Of Advance Research And Innovative Ideas In Education, 10(1), 903-921.
Chicago N Ranjith kumar, D.Bhuvaneshwari, K.Pramod, and M.Rajavardhan reddy. "STABILITY INDICATNG HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF AMBROXOL HCL AND LORATADINE." International Journal Of Advance Research And Innovative Ideas In Education 10, no. 1 (2024) : 903-921.
Oxford N Ranjith kumar, D.Bhuvaneshwari, K.Pramod, and M.Rajavardhan reddy. 'STABILITY INDICATNG HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF AMBROXOL HCL AND LORATADINE', International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 1, 2024, p. 903-921. Available from IJARIIE, https://ijariie.com/AdminUploadPdf/STABILITY_INDICATNG_HPLC_METHOD_DEVELOPMENT_AND_VALIDATION_FOR_ESTIMATION_OF_AMBROXOL_HCL_AND_LORATADINE_ijariie22527.pdf (Accessed : ).
Harvard N Ranjith kumar, D.Bhuvaneshwari, K.Pramod, and M.Rajavardhan reddy. (2024) 'STABILITY INDICATNG HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF AMBROXOL HCL AND LORATADINE', International Journal Of Advance Research And Innovative Ideas In Education, 10(1), pp. 903-921IJARIIE [Online]. Available at: https://ijariie.com/AdminUploadPdf/STABILITY_INDICATNG_HPLC_METHOD_DEVELOPMENT_AND_VALIDATION_FOR_ESTIMATION_OF_AMBROXOL_HCL_AND_LORATADINE_ijariie22527.pdf (Accessed : )
IEEE N Ranjith kumar, D.Bhuvaneshwari, K.Pramod, and M.Rajavardhan reddy, "STABILITY INDICATNG HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF AMBROXOL HCL AND LORATADINE," International Journal Of Advance Research And Innovative Ideas In Education, vol. 10, no. 1, pp. 903-921, Jan-Feb 2024. [Online]. Available: https://ijariie.com/AdminUploadPdf/STABILITY_INDICATNG_HPLC_METHOD_DEVELOPMENT_AND_VALIDATION_FOR_ESTIMATION_OF_AMBROXOL_HCL_AND_LORATADINE_ijariie22527.pdf [Accessed : ].
Turabian N Ranjith kumar, D.Bhuvaneshwari, K.Pramod, and M.Rajavardhan reddy. "STABILITY INDICATNG HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF AMBROXOL HCL AND LORATADINE." International Journal Of Advance Research And Innovative Ideas In Education [Online]. volume 10 number 1 ().
Vancouver N Ranjith kumar, D.Bhuvaneshwari, K.Pramod, and M.Rajavardhan reddy. STABILITY INDICATNG HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF AMBROXOL HCL AND LORATADINE. International Journal Of Advance Research And Innovative Ideas In Education [Internet]. 2024 [Cited : ]; 10(1) : 903-921. Available from: https://ijariie.com/AdminUploadPdf/STABILITY_INDICATNG_HPLC_METHOD_DEVELOPMENT_AND_VALIDATION_FOR_ESTIMATION_OF_AMBROXOL_HCL_AND_LORATADINE_ijariie22527.pdf
BibTex EndNote RefMan RefWorks

Number Of Downloads



Save in Google Drive

Similar-Paper

TitleArea of ResearchAuther NameAction
Impact of Green Chemistry on Indian agriculture, its future and its SWOT analysis.Green ChemistrySharad Bhaskar Dighe Download
Green Chemistry in Plastic Recycling and Waste Management: A Detailed ReviewGreen ChemistryAmol Karbhari Kharde Download
Role of Enzymes in Organic SynthesisChemistryVinod Raosaheb Kadu Download
Solar Panel cell and Its ImportanceScience & Techanology Prof: Kale Balasaheb Popat Download
Hydrogen and fuel cell technologyScience & Techanology Prof: Laware Ramanath Vithalarao Download
Chemistry and applications of organotin (IV) complexes of Schiff bases emphasizing their structural and functional diversityChemistry Dr. N.Y.Badannavar Download
CHARACTERIZATION OF FATTY ACIDS AND ANTIOXIDANT POTENTIAL ANALYSIS IN BAHUNIA RACIMOSA AND CASSIA FISTULA SEEDS OILChemistryJyoti Saini Download
Modified (green) biopolymer Chelates for Industrial Waste Treatment: A step towards environmental sustainabilityGreen (Polymer/ Nano) ChemistryDR. RAJNI BAIS Download
FORMULATION & EVALUATION OF ANTHELMINTIC HERBAL CHOCOLATEpharmacyMr.Sameer s. mahangade Download
Study on prospective green chemistry alternatives for organic synthesis in order to promote sustainable developmentPharmaceutical ChemistryAakash mahajan Download
Pharmacological activities of Transition Metal Complexes of Sulfathiazole drug: A ReviewChemistryRICHA SINGH Download
NEW METHOD DEVELOPMENT AND VALIDATION OF RP- HPLC FOR THE ESTIMATION OF IGURATIMOD IN THE TABLET DOSAGE FORMpharmacyK.Pramod Download
STABILITY INDICATNG HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF AMBROXOL HCL AND LORATADINEpharmacyN Ranjith kumar Download
Structure–Activity Relationship and Docking Analysis of Benzothiazoles as Emerging Anti-Inflammatory Agents: An OverviewPharmaceutical chemistry Deepanshu Download
UVB-Induced Conversion of 7-Dehydrocholesterol to Pre-Vitamin D3chemistryRajani Kumari Download
12
For Authors
  • Submit Paper
  • Processing Charges
  • Submit Payment
Archive
  • Current Issue
  • Past Issue
IJARIIE Board
  • Member Of Board
  • Join As Board
Privacy and Policy
Follow us

Contact Info
  • +91-8401209201 (India)
  • +86-15636082010 (China)
  • ijariiejournal@gmail.com
  • M-20/234 Ami Appt,
    Nr.Naranpura Tele-Exch,
    Naranpura,
    Ahemdabad-380063
    Gujarat,India.
Copyright © 2025. IJARIIE. All Rights Reserved.